Product image of Melatonin Pharma Nord (Melatonin) supplied by GNH India

Melatonin Pharma Nord

Active Ingredient:
Melatonin
Origin:
EU

Melatonin Pharma Nord (Melatonin)

Melatonin, the active ingredient in Melatonin Pharma Nord, is a melatonin receptor agonist presented as an oral tablet for oral use. It assists in aligning the body’s circadian rhythm and is employed to manage insomnia, other sleep disorders, and jet lag in adults and adolescents.

GNH India supplies Melatonin Pharma Nord as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable sourcing and regulatory‑aligned distribution for this sleep‑aid product.

Manufacturer / TM Owner

Pharma Nord Aps (Vojens)

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Indications & Clinical Uses

  • Melatonin acts on melatonin receptors to support the regulation of the sleep‑wake cycle.
  • Insomnia: improves sleep onset and maintenance in individuals with difficulty falling or staying asleep.
  • Sleep disorders: helps normalize circadian rhythm disturbances such as delayed sleep phase.
  • Jet lag: reduces the time required to adjust to new time zones after rapid travel.

How It Works

  • Melatonin binds to MT1 and MT2 receptors in the suprachiasmatic nucleus, mimicking endogenous melatonin. Activation of these G‑protein‑coupled receptors reduces neuronal firing during the night, promoting sleepiness and synchronizing peripheral clocks. This receptor agonism decreases cAMP production and modulates clock‑gene expression, facilitating the transition to sleep and aligning the circadian rhythm with environmental light‑dark cues.

Side Effects

Melatonin may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Drowsiness
  • Headache
  • Dizziness
  • Nausea
  • Vivid dreams
  • Gastrointestinal discomfort

Serious or Rare Side Effects

  • Allergic reaction (rash, itching, swelling)
  • Mood changes (depression, irritability)
  • Hormonal effects (altered menstrual cycle)
  • Severe hypersensitivity (anaphylaxis)
  • Suicidal thoughts (rare)
  • Severe hypotension (very rare)

Precautions & Warnings

  • Consider the following precautions when using Melatonin Pharma Nord.
  • Assess underlying sleep disorder: confirm diagnosis before initiating therapy.
  • Avoid use with shift‑work schedules unless medically advised.
  • Monitor in patients with depression: melatonin may influence mood.
  • Caution in hepatic impairment: metabolism may be reduced.
  • Pregnancy and breastfeeding: safety not established; use only if benefit outweighs risk.
  • Store at ambient temperature below 25°C: keep in original container, protect from moisture and light.

Avoid Interactions

Melatonin can interact with several medicines; awareness of the interaction level is important.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): may increase bleeding risk.
  • Immunosuppressants (e.g., cyclosporine): may reduce efficacy.
  • Sedatives (e.g., benzodiazepines): additive CNS depression.
  • Antidepressants (e.g., fluoxetine): possible serotonin syndrome.

Moderate Interactions (Monitor Closely)

  • Caffeine: may counteract sleep‑promoting effect.
  • Oral contraceptives: may alter melatonin metabolism.
  • Antihypertensives: potential additive hypotensive effect.

Frequently Asked Questions

Melatonin Pharma Nord is used to help regulate the sleep‑wake cycle. It is indicated for the short‑term management of insomnia, various sleep disorders that involve circadian‑rhythm disruption, and for alleviating the symptoms of jet lag after rapid travel across time zones.

Melatonin works by binding to MT1 and MT2 receptors in the brain’s suprachiasmatic nucleus. This activation mimics the natural hormone released at night, signaling the body that it is time to sleep, reducing neuronal activity, and helping to synchronize internal clocks with external light‑dark cycles.

The appropriate dose of Melatonin Pharma Nord is determined by a prescriber based on the individual’s age, condition, and response to therapy. Healthcare professionals tailor the regimen to achieve the desired sleep‑promoting effect while minimizing potential side effects.

Safety of melatonin in pregnancy and lactation has not been definitively established. It should only be used if the prescribing clinician judges that the potential benefit outweighs any possible risk to the mother or infant.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Melatonin differs from traditional sedative hypnotics such as benzodiazepines or Z‑drugs because it acts on physiological sleep‑regulating pathways rather than producing broad CNS depression. It is generally associated with fewer next‑day residual effects, but its efficacy may be limited to circadian‑related sleep disturbances.

Melatonin Pharma Nord should be stored at ambient temperature below 25 °C. Keep the tablets in the original packaging, protect them from moisture and direct light, and ensure the container is tightly closed to maintain product stability.

The product is taken orally, usually with a glass of water. It is commonly administered 30–60 minutes before the intended bedtime, but the exact timing and frequency should follow the prescribing clinician’s instructions.

Serious but rare risks include severe allergic reactions such as anaphylaxis, significant mood alterations like depression or irritability, and hormonal disturbances that may affect menstrual cycles. Patients should seek immediate medical attention if they experience any signs of a severe reaction.

Melatonin should be avoided in individuals with known hypersensitivity to melatonin or any excipients in the formulation, in patients with uncontrolled severe depression, and in those for whom the prescriber determines that the risks outweigh the benefits, such as certain pregnant or breastfeeding women.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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