Product image of Melatonin Teva (Melatonin) supplied by GNH India

Melatonin Teva

Active Ingredient:
Melatonin
Origin:
EU

Melatonin Teva (Melatonin)

Melatonin, the active ingredient in Melatonin Teva, is a melatonin receptor agonist presented as an oral dosage form for oral use. It helps regulate the sleep‑wake cycle and is used to manage insomnia, other sleep disorders and jet lag in adults.

GNH India supplies Melatonin Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva B.V

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Indications & Clinical Uses

Melatonin Teva acts on melatonin receptors to support normal circadian rhythm and facilitate sleep onset.

  • Insomnia: improves sleep initiation and duration in individuals with difficulty falling asleep.
  • Sleep disorders: assists in the management of broader sleep‑related conditions such as delayed sleep phase syndrome.
  • Jet lag: helps synchronize the internal clock after rapid time‑zone travel, reducing fatigue and daytime sleepiness.

How It Works

  • Melatonin Teva contains melatonin, which binds to MT1 and MT2 receptors in the suprachiasmatic nucleus of the hypothalamus. Activation of these G‑protein‑coupled receptors modulates intracellular signaling pathways that promote the physiological decline in core body temperature and other processes that signal the body to prepare for sleep, thereby facilitating the onset of the sleep phase.

Side Effects

Melatonin Teva is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Drowsiness or daytime sleepiness
  • Headache
  • Dizziness
  • Nausea or mild stomach upset
  • Vivid dreams or nightmares
  • Mild fatigue

Serious or Rare Side Effects

  • Allergic reactions such as rash, itching or swelling
  • Severe skin reactions (e.g., Stevens‑Johnson syndrome)
  • Mood changes including depression or anxiety
  • Seizures (rare)
  • Hallucinations or psychotic symptoms
  • Abnormal heart rhythm or palpitations

Precautions & Warnings

When using Melatonin Teva, consider the following safety measures.

  • Assess sleep hygiene: evaluate and improve bedtime routines before initiating therapy.
  • Use lowest effective dose: start with the smallest dose that provides benefit.
  • Avoid operating machinery: refrain from driving or using heavy equipment if residual drowsiness occurs.
  • Hypersensitivity: discontinue if signs of allergic reaction appear.
  • Hepatic impairment: use with caution in patients with liver disease, as metabolism may be altered.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Melatonin may interact with other medicines; monitoring is advised.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Immunosuppressants (e.g., cyclosporine): possible reduction in immunosuppressive effect.
  • Hormonal contraceptives: may diminish contraceptive efficacy.

Moderate Interactions (Monitor Closely)

  • Central nervous system depressants (e.g., benzodiazepines): additive sedative effect.
  • Antidiabetic agents (e.g., insulin): potential alteration of glucose control.
  • Antiepileptic drugs (e.g., carbamazepine): may affect melatonin metabolism.
  • CYP enzyme inhibitors (e.g., fluvoxamine): can raise melatonin plasma levels.

Frequently Asked Questions

Melatonin Teva is used as a sleep aid to help adults who experience difficulty falling asleep, have general sleep‑related disorders, or need assistance adjusting their internal clock after rapid travel across time zones (jet lag). It works by supporting the body’s natural circadian rhythm.

Melatonin binds to MT1 and MT2 receptors in the brain’s suprachiasmatic nucleus, the master clock that regulates circadian rhythms. This receptor activation signals the body that it is nighttime, promoting physiological changes such as a drop in core body temperature and the onset of sleep.

The appropriate dose of Melatonin Teva is determined by the prescribing clinician based on the individual’s age, condition, and response to therapy. Patients should follow the prescriber’s instructions and not alter the dose without medical guidance.

Safety data for melatonin use in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before starting therapy.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Compared with prescription hypnotics such as benzodiazepines, melatonin has a different mechanism focused on circadian regulation rather than direct central nervous system depression, often resulting in a more favorable side‑effect profile. Over‑the‑counter melatonin products may vary in dose and purity, whereas Melatonin Teva is supplied as a regulated pharmaceutical grade product.

Melatonin Teva should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.

Melatonin Teva is taken orally, usually with a glass of water. It is commonly administered 30–60 minutes before the desired bedtime to align with the body’s natural sleep onset period. Patients should follow the timing instructions provided by their prescriber.

Serious but rare risks include severe allergic reactions (rash, swelling, difficulty breathing), mood disturbances such as depression or anxiety, seizures, and abnormal heart rhythms. Any of these symptoms should prompt immediate medical evaluation.

Individuals with known hypersensitivity to melatonin or any excipients in the formulation should avoid use. Caution is also advised for patients with uncontrolled hepatic disease, severe depression, or those taking medications that have major interactions listed above. A healthcare professional should evaluate suitability before initiating therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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