Product image of Melatonin Unimedic Pharma (Melatonin) supplied by GNH India

Melatonin Unimedic Pharma

Active Ingredient:
Melatonin
Origin:
EU

Melatonin Unimedic Pharma (Melatonin)

Melatonin, the active ingredient in Melatonin Unimedic Pharma, is a Melatonin receptor agonist presented as an oral tablet for oral use. It is used to manage sleep disorders such as insomnia and jet lag in adults.

GNH India supplies Melatonin Unimedic Pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Unimedic Pharma Ab

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Indications & Clinical Uses

  • Melatonin acts on the melatonin receptor pathway to regulate circadian rhythm and support sleep.
  • Sleep disorders: helps initiate and maintain sleep in individuals with disturbed sleep patterns.
  • Insomnia: improves sleep onset and reduces nighttime awakenings.
  • Jet lag: assists the body in adjusting to new time zones by synchronising the internal clock.

How It Works

  • Melatonin binds to MT1 and MT2 receptors in the suprachiasmatic nucleus, mimicking endogenous melatonin. This activation modulates the circadian signalling cascade, reduces neuronal firing that promotes wakefulness, and facilitates the transition to sleep, thereby supporting normal sleep‑wake cycles.

Side Effects

Melatonin is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Drowsiness or daytime sleepiness
  • Headache
  • Dizziness
  • Nausea
  • Vivid dreams

Serious or Rare Side Effects

  • Allergic reactions such as rash, itching, or swelling
  • Mood changes including depression or anxiety
  • Hormonal disturbances affecting menstrual cycles
  • Severe daytime somnolence impairing alertness

Precautions & Warnings

  • Melatonin should be used with consideration of individual health status and potential interactions.
  • Assess medical history: review existing conditions and current medications.
  • Avoid operating machinery: do not drive or use heavy equipment if drowsy.
  • Caution with CNS depressants: concurrent use may increase sedation.
  • Pediatric use: not recommended for children without medical supervision.
  • Store at room temperature below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Melatonin may interact with other agents that affect coagulation, neurotransmission, or sedation.

Major Interactions (Avoid)

  • Warfarin: may increase bleeding risk.
  • Fluoxetine: can raise melatonin plasma levels.
  • Benzodiazepines: additive central nervous system depression.

Moderate Interactions (Monitor Closely)

  • Caffeine: may diminish melatonin's sleep‑promoting effect.
  • Alcohol: can enhance sedation and impair coordination.

Frequently Asked Questions

Melatonin Unimedic Pharma contains melatonin, a hormone that helps regulate the sleep‑wake cycle. It is used to treat sleep disorders such as insomnia, to aid adjustment to jet lag, and to support overall sleep quality in adults.

Melatonin acts as an agonist at MT1 and MT2 receptors in the brain’s suprachiasmatic nucleus. By binding these receptors, it signals the body that it is nighttime, helping to synchronize circadian rhythms and promote the onset of sleep.

The appropriate dose is determined by the prescribing healthcare professional based on the individual’s age, condition, and response. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data for melatonin use in pregnancy and lactation are limited. Healthcare providers usually recommend avoiding melatonin unless the potential benefit outweighs any possible risk. Women who are pregnant or nursing should discuss use with their doctor.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Melatonin differs from conventional hypnotics such as benzodiazepines or Z‑drugs because it works by mimicking a natural hormone rather than depressing central nervous system activity. It generally has a milder side‑effect profile and is not habit‑forming, but its efficacy may be lower for severe insomnia.

Melatonin Unimedic Pharma should be stored at room temperature below 25 °C, in the original packaging, and protected from moisture and direct sunlight. Keep the container tightly closed to maintain product stability.

The product is taken orally, typically with a glass of water. It is usually taken 30‑60 minutes before bedtime, but patients should follow the timing advised by their prescriber for optimal effect.

Serious but rare risks include allergic reactions such as rash, swelling, or difficulty breathing, and significant mood changes like depression or anxiety. Any signs of severe reaction should prompt immediate medical attention.

Individuals with known hypersensitivity to melatonin, those taking certain interacting medications (e.g., warfarin, fluoxetine, benzodiazepines) without medical supervision, and children unless specifically prescribed should avoid using melatonin.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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