Product image of Melatonina Aurobindo (Melatonin) supplied by GNH India

Melatonina Aurobindo

Active Ingredient:
Melatonin
Origin:
EU

Melatonina Aurobindo (Melatonin)

Melatonin, the active ingredient in Melatonina Aurobindo, is a melatonin receptor agonist presented as an oral formulation for oral use. It helps regulate the sleep‑wake cycle and is used in adults with insomnia, jet lag, or circadian‑rhythm sleep disorders.

GNH India supplies Melatonina Aurobindo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Aurobindo Pharma (Italia) S.R.L.

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Indications & Clinical Uses

Melatonina Aurobindo acts on melatonin receptors to support normal sleep physiology.

  • Insomnia: facilitates sleep onset and improves sleep continuity in adults with difficulty falling asleep.
  • Jet lag: helps realign the circadian clock after rapid east‑west travel, reducing daytime fatigue.
  • Circadian rhythm sleep disorders: supports entrainment of abnormal sleep‑wake patterns such as shift‑work disorder.

How It Works

  • Melatonin binds to MT1 and MT2 receptors in the suprachiasmatic nucleus, mimicking endogenous melatonin. This interaction modulates the circadian rhythm, lowers core body temperature, and promotes the physiological processes that initiate sleep, thereby facilitating sleep onset and maintenance.

Side Effects

Melatonina Aurobindo is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Headache: mild to moderate pain often reported during initial use.
  • Dizziness: transient sensation of light‑headedness.
  • Daytime sleepiness: residual drowsiness after dosing.
  • Nausea: mild gastrointestinal discomfort.
  • Vivid dreams: unusually intense or memorable dreams.

Serious or Rare Side Effects

  • Allergic reaction: rash, itching, swelling, or anaphylaxis.
  • Severe depression: worsening mood or suicidal thoughts.
  • Seizures: rare occurrence, particularly in predisposed individuals.

Precautions & Warnings

Before using Melatonina Aurobindo, consider the following safety measures.

  • Assess underlying sleep disorder: confirm diagnosis before initiating therapy.
  • Avoid concurrent CNS depressants: limit use with alcohol, benzodiazepines, or antihistamines.
  • Hepatic impairment: use with caution in patients with liver disease.
  • Pediatric use: not recommended for children unless specifically prescribed.
  • Driving and operating machinery: refrain until individual response is known.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Melatonina Aurobindo may interact with other medicines; monitoring is advised.

Major Interactions (Avoid)

  • CNS depressants (e.g., benzodiazepines, opioids): additive sedative effect.
  • Anticoagulants (e.g., warfarin): possible increased bleeding risk.
  • Immunosuppressants (e.g., cyclosporine): may alter melatonin metabolism.

Moderate Interactions (Monitor Closely)

  • Oral contraceptives: melatonin may reduce contraceptive efficacy.
  • Antihypertensives: potential additive blood‑pressure‑lowering effect.
  • Caffeine‑containing products: may diminish melatonin’s sleep‑promoting action.

Frequently Asked Questions

Melatonina Aurobindo contains melatonin, a hormone that helps regulate the sleep‑wake cycle. It is used to treat insomnia, alleviate jet lag after rapid travel across time zones, and manage circadian‑rhythm sleep disorders such as shift‑work disorder.

Melatonin binds to MT1 and MT2 receptors in the brain’s suprachiasmatic nucleus, signaling darkness and promoting the physiological changes that initiate sleep. This receptor activation helps synchronize the internal clock with external light‑dark cycles, facilitating sleep onset and improving sleep quality.

The appropriate dose of Melatonina Aurobindo is determined by a qualified prescriber based on the individual’s age, condition, and response. Patients should follow the healthcare professional’s instructions and not adjust the dose without medical guidance.

Safety data for melatonin use in pregnancy and lactation are limited. Healthcare providers usually recommend avoiding routine use unless the potential benefit outweighs any possible risk. Women who are pregnant, planning pregnancy, or breastfeeding should discuss use with their physician.

To request Melatonina Aurobindo, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Unlike traditional hypnotics such as benzodiazepines, melatonin works by mimicking the body’s natural hormone rather than depressing central nervous system activity. This generally results in fewer next‑day residual effects, but efficacy may be lower for severe insomnia, where prescription hypnotics might be preferred.

Store Melatonina Aurobindo at ambient temperature, below 25 °C, in the original packaging. Keep the product away from moisture, direct sunlight, and extreme heat to maintain potency throughout its shelf life.

Melatonina Aurobindo is taken orally, typically with a glass of water. It is usually administered shortly before the desired bedtime, but the exact timing and frequency should follow the prescriber’s directions.

Serious but rare risks include severe allergic reactions (rash, swelling, anaphylaxis), worsening depression or emergence of suicidal thoughts, and, in very uncommon cases, seizures. Patients should seek immediate medical attention if any of these symptoms occur.

Individuals with known hypersensitivity to melatonin or any excipients, patients taking interacting CNS depressants without medical supervision, and those with uncontrolled severe hepatic disease should avoid using Melatonina Aurobindo unless a physician advises otherwise.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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