Product image of Melatonina Biofarm (Melatonin) supplied by GNH India

Melatonina Biofarm

Active Ingredient:
Melatonin
Origin:
EU

Melatonina Biofarm (Melatonin)

Melatonin, the active ingredient in Melatonina Biofarm, is a melatonin receptor agonist presented as an oral formulation for oral use. It is used to help regulate sleep patterns in adults experiencing insomnia or jet lag.

GNH India supplies Melatonina Biofarm as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Biofarm Sp. Z O.O.

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Indications & Clinical Uses

Melatonina Biofarm, a melatonin receptor agonist, is used to address sleep‑related disorders.

  • Insomnia: helps reduce time to fall asleep and improve sleep continuity.
  • Jet lag: assists in adjusting the circadian rhythm after rapid time‑zone travel.

How It Works

  • Melatonina Biofarm contains melatonin, which binds to MT1 and MT2 receptors in the suprachiasmatic nucleus of the hypothalamus. Activation of these G‑protein‑coupled receptors synchronizes the endogenous circadian clock, promotes the onset of sleep, and modulates downstream hormonal and neuronal pathways that regulate sleep‑wake cycles.

Side Effects

Melatonina Biofarm may cause a range of adverse reactions, which are generally mild but can be serious in rare cases.

Common Side Effects

  • Drowsiness
  • Headache
  • Dizziness
  • Nausea
  • Vivid dreams
  • Mild gastrointestinal discomfort

Serious or Rare Side Effects

  • Allergic reaction (rash, itching, swelling)
  • Mood changes or depression
  • Severe hypotension
  • Hallucinations
  • Persistent daytime sleepiness

Precautions & Warnings

When considering Melatonina Biofarm, several safety measures should be observed.

  • Assess renal or hepatic impairment: adjust use if organ dysfunction is present.
  • Avoid operating machinery: possible residual drowsiness may impair alertness.
  • Consult a healthcare professional if pregnant or breastfeeding: safety data are limited.
  • Review concomitant sedatives: combined use may enhance central nervous system depression.
  • Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Melatonina Biofarm can interact with other medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): melatonin may increase bleeding risk.
  • Immunosuppressants (e.g., cyclosporine): may alter drug levels.
  • Central nervous system depressants (e.g., benzodiazepines): can intensify sedation.

Moderate Interactions (Monitor Closely)

  • Oral contraceptives: melatonin may reduce contraceptive efficacy.
  • Antidepressants (SSRIs, SNRIs): potential for increased serotonergic effects.
  • Caffeine: may diminish melatonin’s sleep‑promoting action.

Frequently Asked Questions

Melatonina Biofarm is a melatonin‑based product indicated for the short‑term management of insomnia and for alleviating the symptoms of jet lag by helping the body adjust its internal clock after rapid travel across time zones.

Melatonin acts as an agonist at the MT1 and MT2 receptors in the brain’s suprachiasmatic nucleus. By activating these receptors, it signals darkness to the body, synchronizes circadian rhythms, and facilitates the transition from wakefulness to sleep.

The appropriate dose of Melatonina Biofarm is determined by a qualified healthcare professional based on the individual’s age, condition, and response. Patients should follow the prescriber’s instructions and not self‑adjust the dosage.

Safety data for melatonin use in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their physician before using Melatonina Biofarm.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with antihistamine‑based or benzodiazepine sleep aids, melatonin offers a physiologic approach by mimicking the body’s natural hormone. It generally has a more favorable safety profile, fewer next‑day residual effects, and is not classified as a controlled substance, though efficacy may vary among individuals.

Store Melatonina Biofarm at room temperature, below 25 °C, in the original packaging. Keep the product away from moisture, direct sunlight and heat sources to maintain potency throughout its shelf life.

Melatonina Biofarm is taken orally, usually with a glass of water. It is commonly taken 30‑60 minutes before the intended bedtime, but the exact timing and frequency should follow the prescribing clinician’s guidance.

Rare but serious adverse events include severe allergic reactions, marked hypotension, mood disturbances such as depression, and persistent daytime sleepiness. Any unexpected or severe symptoms should prompt immediate medical evaluation.

Individuals with known hypersensitivity to melatonin, those taking interacting medications without medical supervision, and patients with uncontrolled severe hepatic or renal disease should avoid using Melatonina Biofarm unless directed by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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