Melatonina Perrigo (Melatonin)

Melatonin binds to MT1 and MT2 receptors in the brain’s suprachiasmatic nucleus. This interaction adjusts the timing of circadian signals, signaling to the body that it is night time, which facilitates the onset of sleep and helps align daily physiological rhythms with the external environment.

The appropriate dose is determined by the prescribing clinician based on the individual’s age, condition, and response. Typical adult regimens range from low to moderate milligram amounts taken shortly before bedtime, but the exact strength and schedule should follow the prescriber’s instructions.

Safety data for melatonin in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before starting the product.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain needs), and required import documentation.

Unlike prescription hypnotics that act on GABA receptors, melatonin works by resetting the circadian clock, offering a more physiological approach to sleep timing. It generally has a milder side‑effect profile than antihistamine‑based over‑the‑counter sleep aids, but its efficacy is most evident for circadian‑related sleep disturbances rather than primary insomnia.

Store the tablets at ambient temperature, preferably below 25 °C. Keep them in the original packaging to protect from moisture and light, and keep out of reach of children. Do not refrigerate or freeze the product.

The product is taken orally as a tablet with a glass of water, usually 30‑60 minutes before the intended bedtime. Swallow the tablet whole; do not crush or chew unless directed by a healthcare professional.

Serious but rare risks include allergic reactions such as rash, swelling, or difficulty breathing, as well as significant mood changes like depression or heightened anxiety. Any signs of severe abdominal pain or anaphylaxis require immediate medical attention.

Individuals with known hypersensitivity to melatonin or any excipients in the tablet should avoid use. Patients taking anticoagulant therapy, immunosuppressants, or those with uncontrolled autoimmune disorders should consult a physician before starting melatonin.