Product image of Melatonina Teva (Melatonin) supplied by GNH India

Melatonina Teva

Active Ingredient:
Melatonin
Origin:
EU

Melatonina Teva (Melatonin)

Melatonin, the active ingredient in Melatonina Teva, is a melatonin receptor agonist presented as an oral formulation for oral use. It is employed to help regulate circadian rhythm and promote sleep onset in adults with insomnia or sleep‑wake rhythm disorders.

GNH India supplies Melatonina Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva B.V

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Indications & Clinical Uses

Melatonina Teva acts on melatonin receptors to address disorders of sleep regulation.

  • Insomnia: reduces sleep onset latency and improves sleep maintenance in adults.
  • Delayed sleep phase disorder: advances sleep timing and aligns circadian rhythm.
  • Non‑24‑hour sleep‑wake rhythm disorder: helps synchronize the sleep‑wake cycle in affected individuals.

How It Works

  • Melatonin binds to MT1 and MT2 receptors in the suprachiasmatic nucleus, mimicking endogenous melatonin. This activation modulates the circadian clock, decreases neuronal firing in the hypothalamus, and facilitates the transition to sleep, thereby normalising the sleep‑wake pattern.

Side Effects

Melatonina Teva may cause a range of adverse reactions.

Common Side Effects

  • Headache: mild to moderate discomfort.
  • Dizziness: transient light‑headedness.
  • Nausea: occasional stomach upset.
  • Daytime drowsiness: residual sleepiness.
  • Vivid dreams: unusual dream patterns.
  • Abdominal discomfort: mild cramps or pain.

Serious or Rare Side Effects

  • Allergic reaction: rash, itching, swelling, or anaphylaxis.
  • Depression: worsening mood or suicidal thoughts.
  • Seizures: rare convulsive episodes.
  • Severe hypotension: marked drop in blood pressure.
  • Cardiac arrhythmia: irregular heart rhythm.

Precautions & Warnings

Before using Melatonina Teva, consider the following safety measures.

  • Pregnancy: consult a healthcare professional; safety data are limited.
  • Breastfeeding: use with caution; limited information on excretion in milk.
  • Elderly patients: start with the lowest effective dose and monitor for excessive sedation.
  • Concomitant CNS depressants: may increase overall sedation; adjust therapy as needed.
  • Anticoagulant therapy: monitor for potential changes in bleeding risk.
  • Store at ambient temperature below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Melatonina Teva can interact with several medication classes.

Major Interactions (Avoid)

  • Anticoagulants: may enhance bleeding tendency.
  • Immunosuppressants: could reduce immunosuppressive efficacy.
  • CYP1A2 inhibitors (e.g., fluvoxamine): increase melatonin plasma levels.

Moderate Interactions (Monitor Closely)

  • CNS depressants (e.g., benzodiazepines): additive sedative effect.
  • Antihypertensives: possible augmentation of blood‑pressure lowering.
  • Oral contraceptives: may alter hormone metabolism and efficacy.

Frequently Asked Questions

Melatonina Teva contains melatonin, a hormone that helps regulate the sleep‑wake cycle. It is prescribed for adults with insomnia, delayed sleep phase disorder, and other sleep‑wake rhythm disturbances to facilitate sleep onset and improve overall sleep quality.

Melatonin binds to MT1 and MT2 receptors in the brain’s suprachiasmatic nucleus, signalling that it is night time. This interaction reduces neuronal activity that promotes wakefulness, aligns the internal clock with external darkness, and encourages the transition to sleep.

The appropriate dose of Melatonina Teva is determined by the prescribing clinician based on the patient’s age, condition severity, and response to therapy. Dosage may vary, and patients should follow the specific instructions provided by their healthcare professional.

Safety data for melatonin use in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their physician before starting Melatonina Teva.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Melatonina Teva differs from traditional hypnotics such as zolpidem or benzodiazepines because it works by mimicking a natural hormone rather than depressing the central nervous system. This mechanism often results in fewer next‑day residual effects, but efficacy may be lower for severe insomnia, where prescription hypnotics might be preferred.

Store Melatonina Teva at ambient temperature below 25 °C, in its original packaging, and protect it from moisture and direct sunlight. Keep the product out of reach of children and avoid storing it in bathrooms or other humid environments.

Melatonina Teva is taken orally, usually with a glass of water. It is commonly administered 30–60 minutes before the desired bedtime, but patients should follow the timing recommended by their prescriber.

Serious adverse reactions, though rare, include severe allergic responses (rash, swelling, anaphylaxis), significant mood changes such as depression or suicidal thoughts, seizures, marked hypotension, and cardiac arrhythmias. Any of these symptoms require immediate medical attention.

Individuals with known hypersensitivity to melatonin or any excipients in the formulation should avoid the product. Patients taking certain anticoagulants, immunosuppressants, or strong CYP1A2 inhibitors should consult their physician, as should those with uncontrolled hypertension, severe depression, or a history of seizures.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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