Product image of Melatoninas Pharma Nord (Melatonin) supplied by GNH India

Melatoninas Pharma Nord

Active Ingredient:
Melatonin
Origin:
EU

Melatoninas Pharma Nord (Melatonin)

Melatonin, the active ingredient in Melatoninas Pharma Nord, is a melatonin receptor agonist presented as an oral tablet for oral use. It is employed to support the regulation of sleep‑wake cycles and to aid individuals experiencing difficulty initiating or maintaining sleep.

GNH India supplies Melatoninas Pharma Nord as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable sourcing for regulated markets. Customers benefit from comprehensive documentation, traceability and responsive technical support throughout the procurement process.

Manufacturer / TM Owner

Pharma Nord Aps (Vojens)

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Indications & Clinical Uses

Melatonin acts on the melatonin receptor system to regulate circadian rhythm and is indicated for several sleep‑related conditions.

  • Insomnia: helps reduce sleep onset latency and improve sleep continuity in adults.
  • Circadian rhythm sleep disorders: assists in aligning the internal clock with external light‑dark cycles.
  • Jet lag: facilitates faster adjustment to new time zones after long‑distance travel.

How It Works

  • Melatonin binds to MT1 and MT2 receptors in the suprachiasmatic nucleus, mimicking the endogenous hormone released by the pineal gland. Activation of these G‑protein‑coupled receptors modulates intracellular signaling pathways that shift circadian phase, promote sleep onset, and stabilize the sleep‑wake cycle without directly inducing sedation.

Side Effects

Melatonin is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Dizziness: transient sensation of light‑headedness.
  • Nausea: occasional stomach upset.
  • Daytime sleepiness: residual drowsiness after dosing.
  • Vivid dreams: unusual or intense dreaming patterns.
  • Mild gastrointestinal discomfort: abdominal cramping or bloating.

Serious or Rare Side Effects

  • Allergic reaction: rash, itching, or swelling.
  • Severe rash: Stevens‑Johnson‑type skin eruption.
  • Depression: worsening mood or depressive symptoms.
  • Hallucinations: visual or auditory disturbances.
  • Worsening of sleep apnea: increased breathing interruptions during sleep.
  • Suicidal thoughts: emergence of self‑harm ideation.

Precautions & Warnings

Before initiating therapy, consider the following safety measures.

  • Assess medical history: evaluate for depression, seizure disorders, or severe hepatic impairment.
  • Review concurrent medications: identify agents that may potentiate sedation.
  • Pregnancy and lactation: discuss potential risks with a healthcare professional.
  • Pediatric use: limit to ages and doses recommended by a prescriber.
  • Elderly patients: start with the lowest effective dose and monitor for confusion.
  • Store at ambient temperature: keep below 25 °C, retain in original packaging, and protect from moisture.

Avoid Interactions

Melatonin may interact with other medicines; some combinations require avoidance while others need monitoring.

Major Interactions (Avoid)

  • CNS depressants: additive sedation may occur.
  • Anticoagulants: possible increase in bleeding risk.
  • Immunosuppressants: melatonin may alter immune modulation.

Moderate Interactions (Monitor Closely)

  • Oral contraceptives: melatonin may reduce contraceptive efficacy.
  • CYP1A2 inhibitors (e.g., fluvoxamine): may raise melatonin plasma levels.
  • CYP1A2 inducers (e.g., smoking, carbamazepine): may lower melatonin exposure.

Frequently Asked Questions

Melatoninas Pharma Nord contains melatonin, which is used to help regulate the sleep‑wake cycle. It is commonly prescribed for insomnia, circadian rhythm sleep disorders such as shift‑work disorder, and for reducing the symptoms of jet lag after rapid travel across time zones.

Melatonin works by binding to MT1 and MT2 receptors in the brain’s suprachiasmatic nucleus. This interaction signals the body that it is nighttime, helping to shift circadian rhythms, promote the onset of sleep, and maintain a stable sleep pattern without causing direct sedation.

The appropriate dose of Melatoninas Pharma Nord is determined by the prescribing clinician based on the patient’s age, condition, and response to therapy. Dosage may vary from low microgram amounts for jet‑lag relief to higher doses for chronic insomnia, and should always follow the prescriber’s instructions.

Safety data for melatonin use in pregnancy and lactation are limited. Healthcare providers usually recommend avoiding melatonin unless the potential benefit outweighs any possible risk. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss alternatives with their physician.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Melatonin differs from traditional hypnotics such as benzodiazepines or Z‑drugs because it acts on the body’s natural circadian system rather than directly depressing the central nervous system. This generally results in fewer next‑day sedation effects, but its efficacy is most pronounced for sleep‑onset problems and circadian misalignment.

Melatoninas Pharma Nord should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in the original container, protect them from moisture and direct sunlight, and ensure the packaging remains sealed until use.

The product is taken orally, usually 30‑60 minutes before the intended bedtime. Tablets should be swallowed whole with a glass of water and not chewed or crushed, unless otherwise directed by a healthcare professional.

Serious but rare risks include severe allergic reactions, worsening of depressive symptoms, hallucinations, and exacerbation of sleep‑apnea syndrome. Patients should seek immediate medical attention if they experience rash, swelling, mood changes, or breathing difficulties while using melatonin.

Melatonin is contraindicated in individuals with known hypersensitivity to the product. It should be used with caution, or avoided, in patients with uncontrolled depression, severe hepatic impairment, or those taking medications that have major interactions, such as certain anticoagulants or CNS depressants, unless supervised by a clinician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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