Product image of Melatonine Bluefish (Melatonin) supplied by GNH India

Melatonine Bluefish

Active Ingredient:
Melatonin
Origin:
EU

Melatonine Bluefish (Melatonin)

Melatonin, the active ingredient in Melatonine Bluefish, is a Melatonin receptor agonist presented as an unknown/unknown for oral use. It helps regulate the circadian rhythm and is used to manage insomnia, jet lag and other sleep disorders in adults.

GNH India supplies Melatonine Bluefish as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bluefish Pharmaceuticals Ab

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Indications & Clinical Uses

Melatonin acts on the melatonin receptor pathway to support normal sleep physiology.

  • Insomnia: facilitates sleep onset and improves sleep continuity.
  • Jet lag: assists rapid adjustment of the internal clock after trans‑meridian travel.
  • General sleep disorders: promotes regular sleep‑wake cycles and reduces nighttime awakenings.

How It Works

  • Melatonin binds to MT1 and MT2 receptors in the suprachiasmatic nucleus, mimicking the endogenous hormone. This agonist activity synchronizes the circadian clock, lowers core body temperature, and enhances the propensity for sleep, thereby supporting the transition from wakefulness to sleep.

Side Effects

Melatonin is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Drowsiness or daytime sleepiness
  • Headache
  • Dizziness
  • Nausea or mild stomach discomfort
  • Vivid dreams or altered dream patterns
  • Mild fatigue

Serious or Rare Side Effects

  • Allergic reactions such as rash, itching or swelling
  • Severe dizziness or fainting
  • Mood changes including depression or anxiety
  • Abnormal heart rhythm or palpitations
  • Hallucinations or confusion
  • Severe skin reactions like Stevens‑Johnson syndrome

Precautions & Warnings

When using melatonin, consider the following safety measures.

  • Consult healthcare provider: before use in children, the elderly, or patients with liver disease.
  • Avoid driving or operating machinery: possible residual drowsiness.
  • Do not combine with alcohol: may increase sedation.
  • Discontinue if allergic reaction occurs: seek medical attention promptly.
  • Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Melatonin can interact with several medication classes.

Major Interactions (Avoid)

  • Anticoagulants: may increase bleeding risk.
  • Immunosuppressants: may reduce melatonin efficacy.
  • CYP1A2 inhibitors (e.g., fluvoxamine): can raise melatonin plasma levels.

Moderate Interactions (Monitor Closely)

  • Sedatives or hypnotics: additive central nervous system depression.
  • Antidepressants (SSRIs): may alter sleep architecture.
  • Caffeine-containing products: may counteract melatonin’s sleep‑promoting effect.

Frequently Asked Questions

Melatonine Bluefish contains melatonin, which is used to help people who have difficulty falling asleep, experience disrupted sleep patterns, or need to adjust their internal clock after crossing time zones. It is commonly indicated for insomnia, jet lag and other sleep‑related disorders.

Melatonin works by binding to MT1 and MT2 receptors in the brain’s suprachiasmatic nucleus, the central regulator of circadian rhythms. This mimics the natural rise in melatonin at night, signaling the body that it is time to sleep and helping to synchronize the sleep‑wake cycle.

The appropriate dose of melatonin is individualized and should be determined by a qualified healthcare professional based on the patient’s age, condition and response. Prescribers set the specific amount and timing that best fits the therapeutic need.

Safety data for melatonin use in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before starting melatonin therapy.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Melatonin differs from prescription hypnotics in that it is a hormone that restores natural circadian signalling rather than directly depressing the central nervous system. It generally has a milder side‑effect profile and is available over the counter, whereas many alternative sleep medications require a prescription and may carry higher risks of dependence.

Melatonine Bluefish should be stored at room temperature, below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.

The product is taken orally, typically with a glass of water. It is usually recommended to ingest the dose shortly before the intended bedtime, following the timing instructions provided by the prescribing clinician.

While rare, serious adverse events can include severe allergic reactions such as rash, swelling or difficulty breathing, as well as significant mood changes like depression or suicidal thoughts. Any sudden or severe symptoms should prompt immediate medical evaluation.

Individuals with known hypersensitivity to melatonin, those taking certain interacting medications (e.g., strong CYP1A2 inhibitors), and patients with uncontrolled severe liver disease should avoid melatonin unless directed otherwise by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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