Product image of Melaxib (Lactulose, Vaseline, Liquid Paraffin) supplied by GNH India

Melaxib

Active Ingredient:
Lactulose, Vaseline, Liquid Paraffin
Origin:
EU

Melaxib (Lactulose, Vaseline, Liquid Paraffin)

Lactulose, Vaseline and Liquid Paraffin, the active ingredients in Melaxib, are a combination laxative presented as an oral solution for oral use. The formulation is intended to relieve constipation and to reduce ammonia absorption in hepatic encephalopathy, primarily in adult patients.

GNH India supplies Melaxib as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, sourcing the product from EU manufacturers and ensuring regulatory compliance for global distribution. The company follows strict quality‑assurance protocols and provides reliable logistics for timely delivery.

Manufacturer / TM Owner

Biocodex

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Melaxib is used to manage conditions related to impaired bowel motility and ammonia accumulation.

  • Constipation: softens stool and promotes bowel movement, helping relieve occasional or chronic constipation.
  • Hepatic encephalopathy: reduces intestinal ammonia production, supporting management of hepatic encephalopathy in patients with liver disease.
  • Bowel preparation for diagnostic procedures: assists in clearing the colon when used as part of a preparation regimen.

How It Works

  • Lactulose is metabolized by colonic bacteria into short‑chain fatty acids, creating an osmotic gradient that retains water in the lumen. The resulting increased fluid softens feces and stimulates peristalsis. Liquid paraffin and vaseline act as stool‑softening lubricants, coating the intestinal contents to reduce surface tension and facilitate smooth passage through the colon. Together, these actions increase stool bulk and frequency, aiding evacuation.

Side Effects

Melaxib may cause a range of adverse reactions, most of which are mild and related to its laxative properties.

Common Side Effects

  • Abdominal cramping: mild discomfort in the abdomen.
  • Flatulence: increased intestinal gas.
  • Diarrhea: loose stools or increased frequency.
  • Nausea: feeling of sickness.

Serious or Rare Side Effects

  • Severe dehydration: marked fluid loss causing dizziness or low blood pressure.
  • Electrolyte imbalance: abnormal potassium or sodium levels.
  • Allergic reaction: rash, itching, swelling, or breathing difficulty.
  • Persistent abdominal pain: ongoing severe pain needing medical evaluation.

Precautions & Warnings

When using Melaxib, certain precautions should be observed to ensure safe and effective therapy.

  • Assess renal function: evaluate kidney status before initiating therapy, especially in patients with renal impairment.
  • Monitor electrolytes: check serum potassium and sodium periodically during prolonged use.
  • Use with caution in diabetes: lactulose may affect blood glucose control.
  • Avoid in intestinal obstruction: do not administer if there is known bowel blockage.
  • Pediatric use: limit to children only under medical supervision.
  • Store at ambient temperature: keep below 25°C in the original container, protect from moisture.

Avoid Interactions

Melaxib can interact with other medicines, altering their effectiveness or increasing adverse effects.

Major Interactions (Avoid)

  • Antacids containing aluminum or magnesium: may reduce lactulose efficacy by affecting osmotic activity.
  • Antibiotics that alter gut flora: can diminish lactulose metabolism and its therapeutic effect.

Moderate Interactions (Monitor Closely)

  • Diuretics: increased risk of electrolyte disturbances when combined with laxative effect.
  • Insulin or oral hypoglycemics: lactulose may affect glucose absorption, requiring dose adjustment.
  • Oral phosphate binders: may interfere with absorption of liquid paraffin.

Frequently Asked Questions

Melaxib is an oral solution that combines lactulose, vaseline and liquid paraffin to treat constipation and to help manage hepatic encephalopathy by lowering intestinal ammonia levels. It is intended for adult patients who need a gentle, osmotic laxative and stool‑softening effect.

Lactulose is a synthetic disaccharide that reaches the colon unchanged, where bacterial enzymes break it down into short‑chain fatty acids. These acids increase the osmotic pressure inside the intestinal lumen, drawing water into the bowel, softening stool and stimulating peristalsis. The added vaseline and liquid paraffin coat the stool, reducing friction and further easing passage.

The dose of Melaxib is individualized by a qualified prescriber based on the patient’s condition, age, renal function and response to therapy. Healthcare professionals determine the volume of oral solution to be taken, the frequency of administration, and any necessary adjustments during treatment.

Safety data for Melaxib in pregnancy and lactation are limited. The product should only be used if the potential benefit justifies any possible risk to the fetus or infant. Pregnant or nursing women should discuss use with their obstetrician or healthcare provider before starting therapy.

To order Melaxib, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide. After the request, the sales team will verify institutional credentials, then provide pricing, availability, shipping details and any required import documentation.

Melaxib combines an osmotic agent (lactulose) with lubricating agents (vaseline and liquid paraffin), offering both stool softening and increased water content. Compared with polyethylene glycol‑based laxatives, Melaxib may provide a milder onset and added benefit for hepatic encephalopathy, whereas PEG products focus solely on osmotic action without the lubricating component.

Melaxib should be stored at ambient temperature, preferably below 25 °C, in its original container to protect it from moisture and light. Keep the bottle tightly closed when not in use and keep out of reach of children.

Melaxib is taken orally as a measured liquid solution. The prescriber will specify the exact volume to be consumed, usually using a calibrated dosing cup or syringe. It can be taken with or without food, and the dose may be adjusted based on clinical response.

The most serious risks include severe dehydration, electrolyte disturbances such as low potassium or sodium, and rare allergic reactions that may present as rash, swelling or breathing difficulty. Patients experiencing these symptoms should seek immediate medical attention.

Melaxib is contraindicated in individuals with known or suspected intestinal obstruction, perforation, or severe inflammatory bowel disease. Patients with hypersensitivity to any of its components (lactulose, vaseline, liquid paraffin) should also avoid its use. A healthcare professional should evaluate suitability before starting therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.