Product image of Melaxose (Lactulose, Vaseline, Liquid Paraffin) supplied by GNH India

Melaxose

Active Ingredient:
Lactulose, Vaseline, Liquid Paraffin
Origin:
EU

Melaxose (Lactulose, Vaseline, Liquid Paraffin)

Lactulose, the active ingredient in Melaxose, is a laxative presented as a combined oral liquid formulation for oral use. Together with Vaseline and liquid paraffin, it is intended to relieve constipation by softening stool and facilitating its passage in both adults and children.

GNH India supplies Melaxose as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Biocodex

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Indications & Clinical Uses

  • Melaxose is a laxative that acts on the gastrointestinal tract to alleviate constipation and related bowel disorders.
  • Constipation: provides relief of infrequent bowel movements and hard stools.
  • Chronic constipation: supports long‑term management of persistent difficulty passing stool.
  • Functional constipation: improves stool consistency in patients without an identifiable organic cause.

How It Works

  • Lactulose is metabolized by colonic bacteria into short‑chain fatty acids, creating an osmotic gradient that retains water in the intestinal lumen; Vaseline and liquid paraffin coat the stool, acting as lubricants that soften the mass and facilitate its transit through the colon.

Side Effects

Melaxose may cause a range of gastrointestinal and systemic reactions.

Common Side Effects

  • Abdominal bloating: feeling of fullness or swelling in the abdomen.
  • Flatulence: increased intestinal gas.
  • Abdominal cramping: mild to moderate stomach cramps.
  • Nausea: sensation of wanting to vomit.
  • Diarrhea or loose stools: watery bowel movements.
  • Mild electrolyte changes: slight shifts in sodium or potassium levels.

Serious or Rare Side Effects

  • Severe electrolyte imbalance: significant hyponatremia or hypokalemia.
  • Dehydration: excessive fluid loss leading to dizziness.
  • Allergic reaction: rash, itching, swelling, or difficulty breathing.
  • Severe abdominal pain: persistent or worsening pain.
  • Rectal bleeding: unusual blood in stool.
  • Rare anaphylaxis: rapid, life‑threatening allergic response.

Precautions & Warnings

  • When prescribing or dispensing Melaxose, consider the following safety measures.
  • Assess renal function: adjust use in patients with impaired kidney function.
  • Monitor electrolytes: watch for hyponatremia or hypokalemia during prolonged therapy.
  • Use with caution in diabetics: lactulose may affect glucose control.
  • Avoid in patients with known hypersensitivity to any component.
  • Pregnancy and breastfeeding: consult a healthcare professional before use.
  • Store at ambient temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Melaxose can interact with other medicines, altering its efficacy or safety.

Major Interactions (Avoid)

  • Antibiotics (e.g., ampicillin): may reduce lactulose effectiveness.
  • Antidiarrheals (e.g., loperamide): can counteract the laxative action.
  • Mineral oil: may interfere with absorption of concomitant drugs.

Moderate Interactions (Monitor Closely)

  • Metformin: may increase gastrointestinal side effects.
  • Probiotics: could alter colonic flora and affect lactulose metabolism.

Frequently Asked Questions

Melaxose is used to treat constipation by softening stool and promoting regular bowel movements. The combination of lactulose, Vaseline, and liquid paraffin works together to increase water content in the intestine and lubricate the stool, making it easier to pass.

Lactulose is broken down by colonic bacteria into short‑chain fatty acids, which create an osmotic gradient that draws water into the intestinal lumen. This increased water softens the stool, while Vaseline and liquid paraffin coat the fecal mass, providing lubrication that facilitates its transit.

The appropriate dose of Melaxose is determined by the prescribing healthcare professional based on the patient’s age, weight, severity of constipation, and clinical response. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety of Melaxose in pregnancy or while breastfeeding has not been fully established. Women who are pregnant, planning to become pregnant, or nursing should discuss potential risks and benefits with their healthcare provider before using this product.

To order Melaxose, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

Melaxose combines an osmotic agent (lactulose) with lubricants (Vaseline and liquid paraffin), offering both water‑drawing and stool‑coating actions. Compared with single‑component laxatives, it may provide more comprehensive relief for hard or dry stools, but individual response varies and choice should be guided by clinical judgment.

Melaxose should be stored at ambient temperature, below 25 °C, in its original packaging. Keep the container tightly closed, protect it from moisture and direct sunlight, and keep it out of reach of children.

Melaxose is taken orally as directed by a healthcare professional. The liquid is usually measured with a calibrated dosing device and swallowed, preferably with water. It can be taken with or without food, but consistency with dosing times helps maintain effectiveness.

Serious risks include severe electrolyte imbalance, dehydration, allergic reactions such as rash or anaphylaxis, and persistent abdominal pain or rectal bleeding. Patients experiencing any of these symptoms should seek medical attention promptly.

Melaxose should be avoided in individuals with known hypersensitivity to lactulose, Vaseline, liquid paraffin, or any excipients in the formulation. It is also contraindicated in patients with intestinal obstruction, perforation, or severe inflammatory bowel disease without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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