Product image of Melaxose, (Lactulose, Vaseline, Liquid Paraffin) supplied by GNH India

Melaxose,

Active Ingredient:
Lactulose, Vaseline, Liquid Paraffin
Origin:
EU

Melaxose, (Lactulose, Vaseline, Liquid Paraffin)

Lactulose, the active ingredient in Melaxose, is an osmotic laxative presented as an oral liquid formulation for oral use. It works to relieve constipation by drawing water into the intestinal lumen and is indicated for use in adults and children who require gentle bowel cleansing.

GNH India supplies Melaxose as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable logistics for global distribution. Customers benefit from consistent product availability and regulatory compliance support.

Manufacturer / TM Owner

Biocodex

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Indications & Clinical Uses

Melaxose, an osmotic laxative, is used to manage constipation by increasing intestinal water content.

  • Constipation: softens stool and promotes regular bowel movements in adults and children.
  • Hepatic encephalopathy: lowers intestinal ammonia absorption, helping to control neuropsychiatric symptoms in patients with liver disease.
  • Pediatric constipation: provides a gentle, age‑appropriate option for relieving constipation in children.

How It Works

  • Lactulose remains largely unabsorbed in the upper gastrointestinal tract and reaches the colon where it is metabolised by bacterial flora into short‑chain fatty acids. This acidifies the colonic contents, drawing water osmotically into the lumen. The added Vaseline and liquid paraffin coat the stool, reducing surface tension and further facilitating smooth passage.

Side Effects

Common Side Effects

  • Abdominal bloating
  • Flatulence
  • Mild diarrhea
  • Nausea

Serious or Rare Side Effects

  • Severe electrolyte imbalance (e.g., low potassium)
  • Allergic reaction such as rash, itching or swelling
  • Persistent abdominal pain or rectal bleeding

Precautions & Warnings

Before using Melaxose, consider the following precautions:

  • Dose adjustment: required in patients with renal impairment.
  • Monitor electrolytes: especially potassium levels during prolonged use.
  • Avoid in intestinal obstruction: may worsen blockage.
  • Caution in diabetes: lactulose can affect blood glucose control.
  • Pregnancy and lactation: safety not established; consult a healthcare professional.
  • Store at ambient temperature: keep in the original container, protect from moisture.

Avoid Interactions

Melaxose may interact with other medicines as follows:

Major Interactions (Avoid)

  • Antibiotics such as neomycin: may reduce lactulose efficacy.
  • Antidiarrheal agents (e.g., loperamide): counteract the laxative effect.

Moderate Interactions (Monitor Closely)

  • Mineral supplements (e.g., magnesium): may increase risk of diarrhea.
  • Diabetes medications: monitor blood glucose as lactulose can alter absorption.
  • Other osmotic laxatives: additive laxative effect may lead to excessive fluid loss.

Frequently Asked Questions

Melaxose is indicated for the relief of constipation in adults and children and for the management of hepatic encephalopathy. The combination of lactulose with Vaseline and liquid paraffin provides both osmotic and lubricating actions to soften stool and promote regular bowel movements.

Lactulose is an osmotic agent that reaches the colon unchanged, where bacterial fermentation produces acids that lower colonic pH. This draws water into the lumen, softening stool. Vaseline and liquid paraffin coat the stool, reducing surface tension and further easing its passage.

The dose of Melaxose is individualized by the prescribing clinician based on the patient’s age, condition severity, and response. Healthcare professionals determine the appropriate volume and frequency to achieve the desired laxative effect while minimizing side effects.

Safety data for Melaxose in pregnancy and lactation are limited, and the product’s pregnancy category is unknown. Women who are pregnant, planning pregnancy, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using the product.

To order Melaxose, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

Compared with other osmotic laxatives such as polyethylene glycol, Melaxose adds a lubricating component (Vaseline and liquid paraffin) that can improve stool softness and ease of passage. This dual mechanism may be advantageous for patients who need both osmotic action and additional stool coating, though individual response varies.

Store Melaxose at ambient temperature below 25 °C, in its original container, and protect it from moisture and direct sunlight. Ensure the cap is tightly closed after each use to maintain product stability and prevent contamination.

Melaxose is taken orally. The prescribed volume can be measured with a calibrated device and, if desired, mixed with a small amount of water or juice to improve palatability. Administration should follow the prescriber’s instructions regarding timing and any dietary considerations.

Serious risks include severe electrolyte disturbances such as hypokalemia, dehydration from excessive diarrhea, allergic reactions (rash, swelling, or anaphylaxis), and persistent abdominal pain or rectal bleeding that may signal an underlying condition requiring medical attention.

Melaxose should be avoided in individuals with known hypersensitivity to lactulose, Vaseline, or liquid paraffin, as well as patients with intestinal obstruction, severe renal impairment, or uncontrolled diabetes without medical supervision. Consultation with a healthcare professional is essential before initiating therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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