Product image of Meldream Pr (Melatonin) supplied by GNH India

Meldream Pr

Active Ingredient:
Melatonin
Origin:
EU

Meldream Pr (Melatonin)

Melatonin, the active ingredient in Meldream Pr, is a melatonin receptor agonist presented as an oral tablet for oral use. It treats insomnia, jet lag and sleep onset difficulties in adults.
GNH India supplies Meldream Pr as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Przedsiębiorstwo Farmaceutyczne Lek-Am Sp. Zo.O.

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Indications & Clinical Uses

  • Melatonin acts on the melatonin receptor pathway to regulate circadian rhythm and is used for sleep‑related disorders.
  • Insomnia: helps reduce the time needed to fall asleep.
  • Jet lag: assists in adjusting the sleep‑wake cycle after rapid time‑zone travel.
  • Sleep onset difficulties: promotes earlier sleep initiation in adults.

How It Works

  • Melatonin binds to MT1 and MT2 receptors in the suprachiasmatic nucleus, mimicking endogenous melatonin. This activation synchronizes the circadian clock, reduces neuronal firing during the night, and facilitates the transition to sleep, thereby supporting normal sleep onset and maintenance.

Side Effects

Melatonin is generally well tolerated, but some users may experience adverse reactions.

Common Side Effects

  • Drowsiness
  • Headache
  • Dizziness
  • Nausea
  • Vivid dreams

Serious or Rare Side Effects

  • Allergic reactions such as rash or itching
  • Mood changes including depression or irritability
  • Hormonal effects such as altered menstrual cycles

Precautions & Warnings

  • Before using Meldream Pr, consider the following safety measures.
  • Assess renal function: adjust use in severe impairment.
  • Avoid use with shift work: efficacy may be reduced.
  • Do not combine with other sedatives without medical advice.
  • Monitor for daytime sleepiness: advise caution when driving.
  • Store at ambient temperature below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Melatonin can interact with several medicines; review the following categories.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): may increase bleeding risk.
  • Immunosuppressants (e.g., cyclosporine): may alter melatonin levels.
  • Central nervous system depressants (e.g., benzodiazepines): additive sedation.

Moderate Interactions (Monitor Closely)

  • Oral contraceptives: may reduce contraceptive efficacy.
  • Antidepressants (e.g., SSRIs): potential for serotonin syndrome.
  • Caffeine: may diminish melatonin’s sleep‑promoting effect.

Frequently Asked Questions

Meldream Pr contains melatonin and is used to help manage sleep‑related conditions such as insomnia, jet lag and difficulty falling asleep. By supporting the body’s natural circadian rhythm, it can improve sleep onset and overall sleep quality in adults.

Melatonin works by binding to MT1 and MT2 receptors in the brain’s master clock, the suprachiasmatic nucleus. This interaction signals that it is nighttime, helping to synchronize the internal clock, lower alertness, and promote the transition to sleep.

The appropriate dose of Meldream Pr is determined by a qualified prescriber based on the individual’s age, condition and response. Patients should follow the specific dosing instructions provided by their healthcare professional and not adjust the dose on their own.

Safety data for melatonin use in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Meldream Pr.

To order Meldream Pr, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Meldream Pr provides a physiological approach by supplementing the body’s natural hormone, whereas many prescription sleep aids (e.g., zolpidem) act on GABA receptors and may cause dependence. Melatonin generally has a milder side‑effect profile but may be less potent for severe insomnia.

Store Meldream Pr at ambient temperature below 25 °C, in its original packaging, and protect it from moisture and direct sunlight. Keep the product out of reach of children and do not use it after the expiration date printed on the label.

Meldream Pr is taken orally, usually 30‑60 minutes before bedtime. It can be swallowed with a small amount of water and may be taken with or without food, depending on the prescriber’s recommendation.

Serious but rare risks include allergic reactions such as rash or itching, significant mood changes like depression or irritability, and hormonal disturbances that may affect menstrual cycles. Users should seek immediate medical attention if any of these symptoms occur.

Meldream Pr is not recommended for children, adolescents, or individuals with severe hepatic impairment without medical supervision. It should also be avoided by patients taking medications that have major interactions listed above, unless a healthcare professional advises otherwise.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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