Product image of Meliam (Meloxicam) supplied by GNH India

Meliam

Active Ingredient:
Meloxicam
Origin:
EU

Meliam (Meloxicam)

Meloxicam, the active ingredient in Meliam, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It is indicated for the management of osteoarthritis, rheumatoid arthritis, musculoskeletal pain and acute pain in adult patients.
GNH India supplies Meliam as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Mibe Pharmaceuticals D.O.O.

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Indications & Clinical Uses

Meloxicam is an NSAID that acts on inflammatory pathways associated with joint and musculoskeletal disorders.

  • Osteoarthritis: reduces joint pain and inflammation, improving function and mobility.
  • Rheumatoid arthritis: alleviates chronic synovial inflammation and associated discomfort.
  • Musculoskeletal pain: provides relief from pain and swelling caused by strains, sprains or overuse.
  • Acute pain: offers short‑term analgesia for sudden inflammatory pain episodes.

How It Works

  • Meloxicam selectively inhibits the cyclooxygenase‑2 (COX‑2) enzyme, decreasing the conversion of arachidonic acid to prostaglandins. By lowering prostaglandin synthesis, it reduces inflammation, pain, and fever while sparing COX‑1 activity, which helps maintain gastric mucosal protection compared with non‑selective NSAIDs.

Side Effects

Common Side Effects

  • Gastro‑intestinal discomfort (nausea, dyspepsia)
  • Headache
  • Dizziness
  • Peripheral edema
  • Elevated blood pressure

Serious or Rare Side Effects

  • Gastro‑intestinal ulceration or bleeding
  • Cardiovascular events such as myocardial infarction or stroke
  • Severe skin reactions (Stevens‑Johnson syndrome, toxic epidermal necrolysis)
  • Renal impairment or failure
  • Hepatic enzyme elevation

Precautions & Warnings

Before initiating therapy, clinicians should evaluate patient‑specific risk factors and monitor for adverse events.

  • Renal function: assess baseline creatinine and adjust use in renal impairment.
  • Blood pressure: monitor regularly, especially in hypertensive patients.
  • Gastro‑intestinal risk: avoid in patients with a history of ulcer disease unless gastro‑protective measures are in place.
  • Hypersensitivity: discontinue if signs of allergic reaction appear.
  • Concomitant anticoagulants: use with caution due to increased bleeding risk.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Meloxicam may interact with several drug classes, requiring careful management.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • Other NSAIDs or COX‑2 inhibitors: additive gastrointestinal toxicity.
  • Selective serotonin reuptake inhibitors (SSRIs): heightened bleeding potential.

Moderate Interactions (Monitor Closely)

  • Diuretics: may reduce renal clearance of meloxicam.
  • Lithium: NSAIDs can raise lithium serum levels.
  • Methotrexate: reduced renal elimination may increase toxicity.
  • Cyclosporine: increased risk of nephrotoxicity.
  • ACE inhibitors or ARBs: may impair renal function, especially in volume‑depleted patients.

Frequently Asked Questions

Meliam contains meloxicam, an NSAID that is prescribed to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, musculoskeletal injuries and short‑term acute pain episodes. It works by targeting inflammatory pathways in the joints and soft tissues, helping patients improve mobility and comfort.

Meloxicam selectively blocks the cyclooxygenase‑2 (COX‑2) enzyme, which is responsible for converting arachidonic acid into prostaglandins that drive inflammation, pain, and fever. By reducing prostaglandin production, meloxicam diminishes the inflammatory response while preserving COX‑1 activity that protects the stomach lining.

The appropriate dose of Meliam is determined by the prescribing healthcare professional based on the individual’s medical condition, severity of symptoms, age, renal function and other factors. Patients should follow the prescriber’s instructions and not adjust the dose without medical advice.

The safety of meloxicam in pregnancy and lactation has not been firmly established. It is generally advised to avoid use during the third trimester and to discuss potential risks with a healthcare provider before taking the medication while pregnant or breastfeeding.

To request Meliam, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Meliam (meloxicam) offers a relatively selective COX‑2 inhibition profile, which may provide comparable analgesic and anti‑inflammatory efficacy to non‑selective NSAIDs while potentially reducing gastrointestinal side effects. However, individual response varies, and clinicians consider patient risk factors, drug interactions and cost when selecting an NSAID.

Meliam should be stored at ambient temperature, below 25 °C (77 °F). Keep the tablets in the original packaging, protect them from moisture, heat and direct sunlight, and ensure the container is tightly closed to maintain product stability.

Meliam is taken orally, usually with a full glass of water. It can be taken with or without food, but patients who experience stomach upset may find it helpful to ingest the tablet with meals. The exact administration schedule is set by the prescribing clinician.

Serious risks include gastrointestinal ulceration or bleeding, cardiovascular events such as heart attack or stroke, severe skin reactions (e.g., Stevens‑Johnson syndrome), and renal or hepatic impairment. Patients should be monitored for signs of these conditions and seek immediate medical attention if they occur.

Meliam is contraindicated in individuals with known hypersensitivity to meloxicam or other NSAIDs, those with active gastrointestinal bleeding or ulcer disease, patients with severe heart failure, and anyone who has experienced a serious allergic reaction to COX‑2 inhibitors. It should also be used with caution in patients with impaired kidney or liver function.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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