Product image of Melitro (Bisacodyl) supplied by GNH India

Melitro

Active Ingredient:
Bisacodyl
Origin:
EU

Melitro (Bisacodyl)

Bisacodyl, the active ingredient in Melitro, is a stimulant laxative presented as an oral tablet for oral use. It is used to relieve constipation and to aid bowel cleansing before medical procedures in adults and children when appropriate.
GNH India supplies Melitro as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Substipharm

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Indications & Clinical Uses

Melitro (bisacodyl) acts on the lower gastrointestinal tract to facilitate bowel movements and is indicated for conditions requiring increased colonic motility.

  • Constipation: provides relief of infrequent or difficult bowel movements.
  • Occasional constipation: helps restore regularity in mild cases.
  • Bowel preparation: assists in cleansing the colon prior to diagnostic or surgical procedures.

How It Works

  • Bisacodyl stimulates intestinal peristalsis by direct action on the colonic mucosa, promoting the release of fluid and electrolytes into the lumen. This increases intraluminal pressure and accelerates transit, resulting in a laxative effect without systemic absorption of significant amounts of the drug.

Side Effects

Bisacodyl may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Abdominal cramps or pain
  • Diarrhea or loose stools
  • Nausea or mild stomach upset
  • Increased thirst or mild dehydration

Serious or Rare Side Effects

  • Severe dehydration or electrolyte imbalance
  • Allergic reactions such as rash or swelling
  • Colonic perforation in cases of misuse
  • Persistent abdominal pain requiring medical evaluation

Precautions & Warnings

When using bisacodyl, consider the following safety measures to minimize risks.

  • Assess renal function: adjust use in patients with renal impairment.
  • Avoid in intestinal obstruction: contraindicated where blockage exists.
  • Use with caution in the elderly: increased susceptibility to dehydration.
  • Do not exceed recommended frequency: follow prescriber guidance.
  • Store at ambient temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Bisacodyl can interact with other medicines, altering its efficacy or safety profile.

Major Interactions (Avoid)

  • Anticholinergic agents: may reduce laxative effectiveness.
  • Loop diuretics: increase risk of electrolyte disturbances.
  • Cardiac glycosides: heightened risk of arrhythmia due to electrolyte shifts.

Moderate Interactions (Monitor Closely)

  • Magnesium‑containing antacids: may potentiate laxative effect.
  • Corticosteroids: may increase risk of colonic perforation.

Frequently Asked Questions

Melitro contains bisacodyl, a stimulant laxative that is used to relieve occasional constipation and to prepare the bowel before diagnostic or surgical procedures. It works by increasing intestinal motility and fluid secretion, helping to produce a bowel movement.

Bisacodyl acts directly on the lining of the colon, stimulating peristaltic activity and promoting the secretion of water and electrolytes into the intestinal lumen. This combination accelerates the movement of stool through the colon, resulting in a laxative effect.

The appropriate dose of Melitro is determined by a qualified prescriber based on the patient’s age, condition, and response to therapy. Patients should follow the specific instructions provided by their healthcare professional and not exceed the recommended amount.

The safety of bisacodyl in pregnancy and lactation has not been definitively established. Healthcare providers should weigh the potential benefits against possible risks before prescribing Melitro to pregnant or nursing individuals.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Compared with osmotic laxatives, bisacodyl provides a more rapid stimulant effect on colonic muscles. It is generally preferred for short‑term relief of constipation and for bowel preparation, whereas osmotic agents are often used for chronic constipation due to a gentler action.

Melitro should be stored at ambient temperature, below 25 °C, in its original packaging. Keep the product away from moisture and direct sunlight to maintain its stability and effectiveness.

Melitro is taken orally, usually with a full glass of water. The tablet should be swallowed whole and not chewed or crushed, unless otherwise directed by a healthcare professional.

Serious risks include severe dehydration, electrolyte imbalance, allergic reactions, and, in rare cases, colonic perforation. Patients should seek immediate medical attention if they experience persistent abdominal pain, signs of severe dehydration, or any allergic symptoms.

Melitro should be avoided in individuals with known intestinal obstruction, acute abdominal conditions, severe dehydration, or hypersensitivity to bisacodyl. It should also be used with caution in the elderly and those with renal impairment.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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