Product image of Mellozzan (Melatonin) supplied by GNH India

Mellozzan

Active Ingredient:
Melatonin
Origin:
EU

Mellozzan (Melatonin)

Melatonin, the active ingredient in Mellozzan, is a melatonin receptor agonist presented as an oral dosage form for oral use. It treats insomnia, jet lag and other sleep disturbances in adults.\n\nGNH India supplies Mellozzan as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Medice Arzneimittel Pütter Gmbh & Co. Kg

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Indications & Clinical Uses

  • Mellozzan, a melatonin receptor agonist, is used to address disorders of the sleep‑wake cycle.\n\nInsomnia: helps initiate and maintain sleep in individuals with difficulty falling asleep.\nJet lag: reduces the time needed to adjust to new time zones after travel.\nCircadian rhythm sleep disorder: supports alignment of the internal clock with desired sleep times.

How It Works

  • Melatonin in Mellozzan binds to MT1 and MT2 receptors in the suprachiasmatic nucleus, mimicking endogenous melatonin. This activation modulates the circadian rhythm, decreases neuronal firing that promotes wakefulness, and facilitates the onset of sleep by signaling the body that it is nighttime.

Side Effects

  • Mellozzan may cause a range of adverse reactions, most of which are mild and transient.\n\nCommon Side Effects:\n- Drowsiness during daytime\n- Headache\n- Dizziness\n- Nausea\n- Vivid dreams\n- Mild gastrointestinal discomfort\n\nSerious or Rare Side Effects:\n- Allergic reactions such as rash, itching or swelling\n- Mood changes including depression or anxiety\n- Hormonal disturbances affecting menstrual cycles\n- Severe hypotension (very low blood pressure)

Precautions & Warnings

  • Before using Mellozzan, consider the following safety measures.\n\nPregnancy: consult a healthcare professional before use.\nBreastfeeding: discuss potential risks with a physician.\nDriving: avoid operating machinery if drowsiness occurs.\nMedication review: inform the prescriber of all concurrent drugs.\nMedical conditions: use cautiously in patients with epilepsy or depression.\nStore at ambient temperature: keep in original container, protect from moisture and direct sunlight.

Avoid Interactions

  • Melatonin can interact with several medicines, requiring attention to avoid reduced efficacy or increased side effects.\n\nMajor Interactions (Avoid):\n- Anticoagulants (e.g., warfarin): may increase bleeding risk.\n- Immunosuppressants (e.g., cyclosporine): potential reduction in drug effectiveness.\n\nModerate Interactions (Monitor Closely):\n- Sedatives or hypnotics: additive sleep‑inducing effect.\n- Antidepressants (e.g., SSRIs): possible alteration of melatonin metabolism.\n- Caffeine or stimulants: may counteract sleep‑promoting action.

Frequently Asked Questions

Mellozzan contains melatonin and is used to help manage insomnia, jet lag and other sleep disturbances that arise from circadian rhythm misalignment. It supports the natural sleep‑wake cycle by providing an exogenous source of the hormone that signals the body it is time to rest.

Melatonin in Mellozzan binds to MT1 and MT2 receptors in the brain’s suprachiasmatic nucleus. This interaction signals darkness to the body, helping to synchronize the internal clock, reduce alertness, and promote the onset of sleep.

The appropriate dose of Mellozzan is determined by the prescribing healthcare professional based on the individual’s age, condition and response. Patients should follow the prescriber’s instructions and not adjust the dose without medical advice.

Safety data for melatonin in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Mellozzan.

To order Mellozzan, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Unlike many prescription hypnotics, melatonin works by mimicking a natural hormone rather than depressing central nervous system activity. This generally results in a lower risk of dependence, but its efficacy may be more modest and is best suited for sleep problems linked to circadian rhythm disturbances.

Mellozzan should be stored at ambient temperature, below 25 °C, in its original packaging. Protect the product from moisture, excessive heat and direct sunlight to maintain its stability and potency.

Mellozzan is taken orally, usually with a glass of water. It is commonly taken 30‑60 minutes before bedtime, but the exact timing should follow the prescriber’s guidance.

Serious risks, though rare, include severe allergic reactions such as rash, swelling or difficulty breathing, and hormonal disturbances that may affect menstrual cycles or mood. Any signs of an allergic response or unexpected psychological changes should prompt immediate medical attention.

Individuals with known hypersensitivity to melatonin, those taking certain anticoagulants or immunosuppressants without medical supervision, and patients with uncontrolled epilepsy or severe depression should avoid using Mellozzan unless directed by a qualified healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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