Product image of Melocalm (Meloxicam) supplied by GNH India

Melocalm

Active Ingredient:
Meloxicam
Origin:
EU

Melocalm (Meloxicam)

Meloxicam, the active ingredient in Melocalm, is a NSAID presented as an oral tablet for oral use. It is indicated for the relief of pain and inflammation associated with osteoarthritis, rheumatoid arthritis and other musculoskeletal conditions in adult patients.

GNH India supplies Melocalm as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bennett Pharmaceuticals Sa

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Indications & Clinical Uses

Melocalm, a non‑steroidal anti‑inflammatory drug, acts on inflammatory pathways that underlie several joint and musculoskeletal disorders.

  • Osteoarthritis: reduces joint pain and improves functional mobility.
  • Rheumatoid arthritis: decreases inflammation and slows disease‑related joint damage.
  • Musculoskeletal pain: alleviates acute and chronic pain associated with strains, sprains and overuse injuries.

How It Works

  • Meloxicam selectively inhibits cyclo‑oxygenase‑2 (COX‑2) enzymes, leading to decreased synthesis of prostaglandins that mediate inflammation, pain and fever. By sparing COX‑1 activity, it aims to maintain gastric mucosal protection while providing anti‑inflammatory and analgesic effects.

Side Effects

Meloxicam may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Dyspepsia: upset stomach or indigestion.
  • Headache: mild to moderate head pain.
  • Dizziness: sensation of light‑headedness.
  • Peripheral edema: swelling of the lower limbs.
  • Hypertension: elevated blood pressure.

Serious or Rare Side Effects

  • Gastrointestinal ulcer or bleeding: potentially life‑threatening bleeding in the stomach or intestines.
  • Cardiovascular events: increased risk of heart attack or stroke.
  • Renal impairment: reduced kidney function or acute kidney injury.
  • Hepatic injury: signs of liver damage such as jaundice.
  • Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.

Precautions & Warnings

When prescribing or dispensing Melocalm, consider the following safety measures.

  • Assess gastrointestinal risk: evaluate history of ulcers or bleeding.
  • Monitor renal function: check serum creatinine and urine output regularly.
  • Evaluate cardiovascular status: use caution in patients with heart disease.
  • Use lowest effective dose: limit duration to the shortest period necessary.
  • Avoid in known hypersensitivity: discontinue if allergic reactions occur.
  • Store at below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Meloxicam can interact with several drug classes, requiring careful management.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Lithium: elevated lithium serum levels.

Moderate Interactions (Monitor Closely):\n- Methotrexate: potential for enhanced toxicity.

  • ACE inhibitors or ARBs: possible reduction in renal function.
  • Diuretics: may exacerbate fluid retention and affect blood pressure.

Frequently Asked Questions

Melocalm, containing meloxicam, is prescribed to manage pain and inflammation in osteoarthritis, rheumatoid arthritis and other musculoskeletal disorders such as acute sprains or strains. It helps reduce joint swelling, improve mobility and alleviate chronic pain associated with these conditions.

Meloxicam works by selectively inhibiting the cyclo‑oxygenase‑2 (COX‑2) enzyme, which reduces the production of prostaglandins—chemical mediators that cause inflammation, pain and fever. By targeting COX‑2, it provides anti‑inflammatory and analgesic effects while sparing COX‑1 activity that protects the stomach lining.

The appropriate dose of Melocalm is determined by the prescribing clinician based on the patient’s medical condition, severity of symptoms, age, renal and hepatic function, and other individual factors. Patients should follow the prescriber’s instructions and not alter the dose without medical advice.

The safety of meloxicam in pregnancy and lactation has not been fully established. It should only be used if the potential benefit justifies the potential risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss alternatives with their healthcare provider.

To request Melocalm, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Melocalm (meloxicam) offers relatively selective COX‑2 inhibition, which may lower the risk of gastrointestinal irritation compared with non‑selective NSAIDs like ibuprofen or naproxen. However, it still carries cardiovascular and renal risks similar to other NSAIDs, and the choice of therapy should be individualized based on patient risk factors.

Melocalm tablets should be stored at temperatures below 25 °C, in their original packaging, and protected from moisture and direct sunlight. Do not store in bathrooms or near heat sources. Keep out of reach of children.

Melocalm is taken orally, usually with a full glass of water. It may be taken with or without food, but taking it with food can help reduce stomach upset. Swallow the tablet whole; do not crush, chew, or split unless instructed by a healthcare professional.

Serious risks include gastrointestinal ulceration or bleeding, cardiovascular events such as heart attack or stroke, renal impairment leading to reduced kidney function, severe liver injury, and rare but life‑threatening skin reactions like Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they notice signs of these conditions.

Melocalm should be avoided in individuals with known hypersensitivity to meloxicam or other NSAIDs, those with active gastrointestinal ulceration or bleeding, severe heart failure, uncontrolled hypertension, and in patients with severe renal or hepatic impairment unless specifically directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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