Product image of Meloprol (Meloxicam) supplied by GNH India

Meloprol

Active Ingredient:
Meloxicam
Origin:
EU

Meloprol (Meloxicam)

Meloxicam, the active ingredient in Meloprol, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an injectable solution for intramuscular use. It provides analgesic and anti‑inflammatory effects for pain relief, osteoarthritis, rheumatoid arthritis and other musculoskeletal inflammatory conditions in adult patients.

GNH India supplies Meloprol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and regulatory requirements across EU and global markets.

Manufacturer / TM Owner

Energon Pharmaceuticals Ltd

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Indications & Clinical Uses

Meloprol (meloxicam) is used to manage pain and inflammation associated with several musculoskeletal disorders.

  • Pain relief: reduces moderate to severe pain in acute and chronic settings.
  • Osteoarthritis: improves joint function and decreases stiffness.
  • Rheumatoid arthritis: lessens joint swelling and pain, slowing disease progression.
  • Musculoskeletal inflammation: alleviates inflammation from injuries or overuse.

How It Works

  • Meloxicam reversibly inhibits cyclooxygenase (COX) enzymes, with a preference for COX‑2 over COX‑1. This inhibition reduces the conversion of arachidonic acid to prostaglandins, leading to decreased synthesis of mediators that cause pain, fever, and inflammation at the site of tissue injury.

Side Effects

Adverse reactions to meloxicam may vary in frequency and severity.

Common Side Effects

  • Gastrointestinal upset: nausea, dyspepsia, or abdominal pain.
  • Headache: mild to moderate intensity.
  • Dizziness or vertigo.
  • Injection‑site pain or erythema.
  • Mild rash or pruritus.
  • Transient increase in blood pressure.

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding, potentially life‑threatening.
  • Severe skin reactions such as Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Hepatic enzyme elevation or liver injury.
  • Acute renal impairment or failure.
  • Anaphylaxis or severe hypersensitivity reactions.
  • Cardiovascular events including myocardial infarction or stroke.

Precautions & Warnings

When prescribing meloxicam, clinicians should consider several safety precautions.

  • Assess renal function: avoid use in patients with severe renal impairment.
  • Monitor hepatic enzymes: use cautiously in liver disease.
  • Avoid in known hypersensitivity to NSAIDs or aspirin.
  • Use with caution in cardiovascular disease: increased risk of thrombotic events.
  • Limit use in elderly patients: higher risk of gastrointestinal complications.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Meloxicam can interact with other medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Other NSAIDs or COX‑2 inhibitors: additive gastrointestinal toxicity.
  • Selective serotonin reuptake inhibitors (SSRIs): heightened bleeding tendency.
  • ACE inhibitors or ARBs: possible renal impairment.
  • Lithium: increased serum lithium levels.

Moderate Interactions (Monitor Closely)

  • Diuretics: may reduce renal perfusion.
  • Methotrexate: reduced clearance, risk of toxicity.
  • Cyclosporine: increased nephrotoxicity.
  • Corticosteroids: additive gastrointestinal risk.
  • Beta‑blockers: may blunt antihypertensive effect.

Frequently Asked Questions

Meloprol contains meloxicam, an NSAID indicated for the relief of moderate to severe pain and for reducing inflammation in conditions such as osteoarthritis, rheumatoid arthritis and other musculoskeletal inflammatory disorders.

Meloxicam blocks cyclooxygenase enzymes, especially COX‑2, which limits the production of prostaglandins—chemical mediators that cause pain, fever and swelling. By reducing prostaglandin levels, the drug provides analgesic and anti‑inflammatory effects.

The appropriate dose of Meloprol is determined by the prescribing healthcare professional based on the patient’s condition, severity of symptoms, renal and hepatic function, and other individual factors. No fixed regimen is provided here.

Safety data for meloxicam during pregnancy and lactation are limited. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and the decision must be made by a qualified prescriber.

To request Meloprol, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain where required) and any necessary import documentation.

Melox​icam, the active component of Meloprol, offers a longer half‑life and preferential COX‑2 inhibition compared with many non‑selective NSAIDs, which may translate into once‑daily dosing and potentially lower gastrointestinal risk, though individual response and safety profiles vary.

Meloprol should be stored at 2‑8 °C, kept refrigerated, protected from light, and must not be frozen or shaken. Use aseptic technique when preparing the injectable solution, and discard any product that appears discolored or contaminated.

Meloprol is supplied as an injectable solution for intramuscular injection. The injection is performed by a qualified healthcare professional using aseptic technique, typically into a large muscle such as the gluteus or deltoid, according to the prescriber’s instructions.

Serious risks include gastrointestinal ulceration or bleeding, severe skin reactions (e.g., Stevens‑Johnson syndrome), liver injury, acute kidney failure, anaphylaxis, and cardiovascular events such as heart attack or stroke. Patients should be monitored closely for any signs of these conditions.

Meloprol is contraindicated in patients with known hypersensitivity to meloxicam or other NSAIDs, those with active gastrointestinal bleeding, severe renal or hepatic impairment, and in individuals who have experienced a recent myocardial infarction or stroke unless specifically advised by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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