Product image of Meloxicam Aurobindo (Meloxicam) supplied by GNH India

Meloxicam Aurobindo

Active Ingredient:
Meloxicam
Origin:
EU

Meloxicam Aurobindo (Meloxicam)

Meloxicam, the active ingredient in Meloxicam Aurobindo, is a nonsteroidal anti-inflammatory drug presented as an oral tablet for oral use. It is indicated for the management of osteoarthritis, rheumatoid arthritis, juvenile rheumatoid arthritis, ankylosing spondylitis and acute pain in adult patients.

GNH India supplies Meloxicam Aurobindo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑approved products to a global network of healthcare providers, including public and private sector institutions.

Manufacturer / TM Owner

Aurobindo Pharma B.V.

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Indications & Clinical Uses

Meloxicam is an NSAID that reduces inflammation and pain by targeting the cyclooxygenase pathway.

  • Osteoarthritis: reduces joint pain and improves mobility.
  • Rheumatoid arthritis: decreases synovial inflammation and slows disease progression.
  • Juvenile rheumatoid arthritis: alleviates pain and swelling in pediatric patients.
  • Ankylosing spondylitis: mitigates spinal stiffness and discomfort.
  • Acute pain: provides rapid relief of moderate to severe pain episodes.

How It Works

  • Meloxicam preferentially inhibits the cyclooxygenase‑2 (COX‑2) enzyme, leading to decreased synthesis of prostaglandins that mediate inflammation, pain, and fever. By sparing COX‑1 activity to a greater extent, it aims to maintain gastric mucosal protection while delivering anti‑inflammatory and analgesic effects.

Side Effects

Common Side Effects

  • Dyspepsia: stomach discomfort or indigestion.
  • Nausea: feeling of sickness or urge to vomit.
  • Headache: mild to moderate head pain.
  • Dizziness: sensation of light‑headedness or unsteadiness.
  • Peripheral edema: mild swelling of the lower limbs.
  • Elevated blood pressure: modest increase in systolic or diastolic values.

Serious or Rare Side Effects

  • Gastrointestinal ulcer or bleeding: potentially life‑threatening hemorrhage.
  • Cardiovascular events: increased risk of heart attack or stroke.
  • Severe skin reactions: such as Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Hepatic injury: elevated liver enzymes or hepatitis.
  • Renal impairment: acute kidney injury or worsening of chronic kidney disease.

Precautions & Warnings

Before initiating therapy, consider the following precautions:

  • Assess renal function: monitor serum creatinine and eGFR.
  • Evaluate hepatic status: check liver enzymes in patients with liver disease.
  • Monitor blood pressure: watch for hypertension, especially in cardiovascular risk groups.
  • Review concomitant NSAID or anticoagulant use: avoid additive bleeding risk.
  • Use lowest effective dose: limit duration to the shortest period needed for symptom control.
  • Store at ambient temperature: keep below 25 °C in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Meloxicam may interact with several drug classes, requiring careful management.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • Lithium: meloxicam can raise lithium serum concentrations.
  • Methotrexate: heightened methotrexate toxicity.
  • SSRIs or SNRIs: additive bleeding risk.

Moderate Interactions (Monitor Closely):\n- ACE inhibitors or ARBs: possible reduction in renal function.

  • Diuretics: may diminish antihypertensive effect.
  • Cyclosporine: increased nephrotoxicity risk.

Frequently Asked Questions

Meloxicam Aurobindo is an oral NSAID indicated for the treatment of osteoarthritis, rheumatoid arthritis, juvenile rheumatoid arthritis, ankylosing spondylitis, and for the relief of moderate to severe acute pain in adult patients.

Meloxicam works by preferentially inhibiting the cyclooxygenase‑2 (COX‑2) enzyme, which reduces the production of prostaglandins that cause inflammation, pain, and fever, thereby providing anti‑inflammatory and analgesic effects.

The appropriate dose of meloxicam is determined by the prescribing clinician based on the patient’s condition, age, renal and hepatic function, and response to therapy. Dosage may vary from low‑dose regimens for chronic arthritis to higher doses for acute pain.

Safety of meloxicam in pregnancy and lactation is not well established. It should be avoided unless the potential benefit justifies the potential risk to the fetus or infant, and the decision should be made by a qualified health professional.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Meloxicam offers a longer half‑life and greater COX‑2 selectivity than many traditional NSAIDs such as ibuprofen or diclofenac, which may translate into once‑daily dosing and a potentially lower risk of gastrointestinal irritation, though individual response and safety profiles vary.

Store the tablets at ambient temperature, preferably below 25 °C. Keep them in the original blister or container, protect from moisture and direct sunlight, and keep out of reach of children.

Meloxicam Aurobindo is taken orally with a full glass of water. It may be taken with or without food, but patients who experience stomach upset are advised to take it with meals.

Serious risks include gastrointestinal ulceration or bleeding, cardiovascular events such as heart attack or stroke, severe skin reactions (e.g., Stevens‑Johnson syndrome), hepatic injury, and acute renal impairment, especially in patients with pre‑existing organ dysfunction.

Meloxicam should be avoided in individuals with known hypersensitivity to meloxicam or other NSAIDs, active gastrointestinal ulcer or bleeding, severe renal or hepatic impairment, uncontrolled hypertension, and in pregnant women at risk of fetal complications.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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