Product image of Meloxicam Tetrafarma (Meloxicam) supplied by GNH India

Meloxicam Tetrafarma

Active Ingredient:
Meloxicam
Origin:
EU

Meloxicam Tetrafarma (Meloxicam)

Meloxicam, the active ingredient in Meloxicam Tetrafarma, is a Nonsteroidal anti-inflammatory drug (NSAID) presented as an oral dosage form for oral use. It is used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, and acute musculoskeletal conditions in adult patients.

GNH India supplies Meloxicam Tetrafarma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The product complies with EU manufacturing standards and is distributed under strict quality controls.

Manufacturer / TM Owner

Tetrafarma- Produtos Farmacêuticos, Lda.

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Indications & Clinical Uses

Meloxicam belongs to the NSAID class and is indicated for inflammatory joint and musculoskeletal disorders.

  • Osteoarthritis: reduces joint pain and swelling, improving mobility.
  • Rheumatoid arthritis: alleviates inflammatory joint symptoms and slows functional decline.
  • Acute musculoskeletal pain: provides rapid analgesia for injuries or post‑operative discomfort.

How It Works

  • Meloxicam preferentially inhibits cyclooxygenase‑2 (COX‑2) enzymes, leading to decreased conversion of arachidonic acid to prostaglandins. The reduced prostaglandin synthesis diminishes inflammation, pain, and fever while sparing COX‑1 activity, which helps maintain gastric mucosal protection and platelet function compared with non‑selective NSAIDs.

Side Effects

Meloxicam may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia, or abdominal pain.
  • Headache: mild to moderate intensity.
  • Dizziness or vertigo.
  • Peripheral edema: swelling of the lower limbs.
  • Elevated blood pressure.
  • Skin rash or pruritus.

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding.
  • Cardiovascular events such as myocardial infarction or stroke.
  • Hepatic enzyme elevation or liver injury.
  • Severe skin reactions (e.g., Stevens‑Johnson syndrome).
  • Acute renal impairment or failure.
  • Anaphylactic or severe hypersensitivity reactions.

Precautions & Warnings

Before prescribing Meloxicam, clinicians should evaluate patient‑specific risk factors and monitor for adverse outcomes.

  • Renal function: monitor in patients with existing kidney disease.
  • Cardiovascular risk: use cautiously in patients with hypertension or heart disease.
  • Gastrointestinal risk: assess history of ulcers or bleeding.
  • Pregnancy and lactation: avoid unless benefits outweigh risks.
  • Drug interactions: review concomitant NSAIDs, anticoagulants, and antihypertensives.
  • Store at ambient temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Meloxicam can interact with several drug classes, requiring careful assessment.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Selective COX‑2 inhibitors: additive toxicity.
  • Lithium: increased serum lithium levels.
  • Methotrexate: reduced clearance and potential toxicity.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: possible renal function changes.
  • Diuretics: heightened risk of renal impairment.
  • SSRIs or SNRIs: increased bleeding tendency.

Frequently Asked Questions

Meloxicam Tetrafarma is prescribed to manage pain and inflammation in osteoarthritis, rheumatoid arthritis, and acute musculoskeletal conditions such as sprains, strains, or post‑surgical discomfort. It helps improve joint function and reduces swelling in adult patients.

Meloxicam works by selectively inhibiting the cyclooxygenase‑2 (COX‑2) enzyme, which reduces the production of prostaglandins—chemical mediators that cause inflammation, pain, and fever. By lowering prostaglandin levels, meloxicam diminishes the inflammatory response while sparing COX‑1 activity that protects the stomach lining.

The appropriate dose of Meloxicam Tetrafarma is determined by the prescribing clinician based on the patient’s condition, severity, and overall health. Dosage adjustments may be needed for renal or hepatic impairment, and the prescriber will provide specific instructions.

Meloxicam is generally not recommended during pregnancy, especially in the third trimester, because of potential risks to the fetus. It should also be used with caution while breastfeeding, as it may pass into breast milk. The prescriber will weigh benefits against risks for each individual.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Meloxicam offers a more selective COX‑2 inhibition compared with non‑selective NSAIDs such as ibuprofen or naproxen, which may result in a lower incidence of gastrointestinal side effects. However, cardiovascular and renal risks remain, and the choice of NSAID should be individualized based on patient risk factors.

Meloxicam Tetrafarma should be stored at ambient temperature, below 25 °C, in its original packaging. Protect the product from moisture, direct sunlight, and extreme temperature fluctuations to maintain its stability and potency.

Meloxicam Tetrafarma is taken orally, usually with or without food as directed by the prescriber. Swallow the tablet whole with a full glass of water; do not crush or chew unless specifically instructed.

Serious risks include gastrointestinal ulceration or bleeding, cardiovascular events such as heart attack or stroke, severe skin reactions, liver injury, and acute kidney damage. Patients should be monitored for signs of these conditions and seek immediate medical attention if they occur.

Meloxicam should be avoided in patients with known hypersensitivity to meloxicam or other NSAIDs, active gastrointestinal ulceration, severe heart failure, or uncontrolled hypertension. It is also contraindicated in the third trimester of pregnancy and in individuals with significant renal or hepatic impairment unless the prescriber decides otherwise.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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