Product image of Melpor (Meloxicam) supplied by GNH India

Melpor

Active Ingredient:
Meloxicam
Origin:
EU

Melpor (Meloxicam)

Meloxicam, the active ingredient in Melpor, is a nonsteroidal anti-inflammatory drug presented as an oral tablet for oral use. It is indicated for the management of pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute musculoskeletal pain, and post‑operative pain in adult patients.

GNH India supplies Melpor as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑approved batches to meet global demand, with reliable logistics and comprehensive documentation.

Manufacturer / TM Owner

Sidefarma - Sociedade Industrial De Expansão Farmacêutica, S.A.

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Indications & Clinical Uses

  • Meloxicam is used to treat inflammatory and degenerative joint conditions by reducing pain and swelling.
  • Osteoarthritis: reduces joint pain and improves function.
  • Rheumatoid arthritis: decreases inflammation and slows disease progression.
  • Ankylosing spondylitis: alleviates spinal stiffness and pain.
  • Acute musculoskeletal pain: provides rapid relief of pain and inflammation.
  • Post‑operative pain: helps control pain after surgical procedures.

How It Works

  • Meloxicam reversibly inhibits cyclooxygenase enzymes COX‑1 and COX‑2, with a higher affinity for COX‑2. By blocking COX‑2–mediated conversion of arachidonic acid to prostaglandins, it lowers prostaglandin synthesis at sites of inflammation, thereby diminishing pain, swelling, and fever while preserving gastric mucosal protection relative to non‑selective NSAIDs. The selective inhibition results in a longer half‑life, allowing once‑daily dosing in many patients, and contributes to its efficacy in chronic musculoskeletal disorders.

Side Effects

Meloxicam may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Gastrointestinal discomfort or dyspepsia
  • Nausea or vomiting
  • Headache or dizziness
  • Mild peripheral edema
  • Transient increase in blood pressure

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding
  • Cardiovascular events such as myocardial infarction or stroke
  • Acute renal impairment or failure
  • Severe skin reactions (e.g., Stevens‑Johnson syndrome)
  • Elevated liver enzymes or hepatitis
  • Anaphylactic or severe allergic reactions

Precautions & Warnings

  • When prescribing meloxicam, clinicians should consider several safety measures.
  • Assess renal function: evaluate baseline kidney function before initiating therapy.
  • Monitor hepatic enzymes: check liver function tests periodically.
  • Avoid in patients with known hypersensitivity to NSAIDs: contraindicated.
  • Use lowest effective dose: minimize risk of gastrointestinal complications.
  • Consider gastroprotective agents: co‑prescribe a proton pump inhibitor if risk factors present.
  • Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

Avoid Interactions

Meloxicam can interact with other medicines, requiring careful management.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Selective serotonin reuptake inhibitors (SSRIs): heightened gastrointestinal bleeding risk.
  • Other NSAIDs or COX‑2 inhibitors: additive toxicity.
  • Lithium: reduced renal clearance leading to toxicity.
  • Methotrexate: decreased renal elimination, possible toxicity.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce renal function, monitor creatinine.
  • Diuretics: risk of renal impairment, monitor electrolytes.
  • Corticosteroids: increased ulcer risk, consider gastroprotection.

Frequently Asked Questions

Melpor contains meloxicam, an NSAID that is prescribed to relieve pain and inflammation in conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute musculoskeletal injuries, and after surgical procedures. It works by reducing the inflammatory response in the affected joints and tissues.

Meloxicam blocks the activity of cyclooxygenase enzymes COX‑1 and COX‑2, especially COX‑2, which are needed to convert arachidonic acid into prostaglandins. By lowering prostaglandin production at sites of inflammation, the drug diminishes pain, swelling, and fever while preserving some gastric protection compared with non‑selective NSAIDs.

The appropriate dose of meloxicam is determined by the prescribing healthcare professional based on the specific indication, patient age, renal and hepatic function, and other individual factors. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

The safety of meloxicam during pregnancy and lactation has not been definitively established. It is generally advised to avoid use unless the potential benefit justifies the potential risk to the fetus or infant, and it should be prescribed only after careful consideration by a qualified clinician.

To request Melpor, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Meloxicam offers a longer half‑life and greater COX‑2 selectivity than many traditional NSAIDs, allowing once‑daily dosing for many patients and potentially lower gastrointestinal risk. However, it still shares class‑related risks such as cardiovascular and renal effects, so selection should be individualized based on patient comorbidities.

Melpor should be stored at ambient temperature, preferably below 25 °C, in its original packaging to protect it from moisture and direct sunlight. Keep the product out of reach of children and do not use it after the expiry date printed on the label.

Melpor is taken orally, usually with a full glass of water. It may be taken with or without food, but patients who experience stomach upset are often advised to take it with meals. Swallow the tablet whole; do not crush or chew it.

Serious adverse events include gastrointestinal bleeding or ulceration, cardiovascular events such as heart attack or stroke, acute kidney injury, severe skin reactions (e.g., Stevens‑Johnson syndrome), and liver injury. Patients should seek immediate medical attention if they notice signs like black stools, chest pain, sudden swelling, rash, or jaundice.

Meloxicam is contraindicated in individuals with known hypersensitivity to meloxicam or other NSAIDs, those with active gastrointestinal ulceration or bleeding, severe heart failure, and patients who have had a recent coronary artery bypass graft. Caution is also required in patients with impaired renal or hepatic function.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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