Product image of Memantin 1 A Pharma (Memantine Hydrochloride) supplied by GNH India

Memantin 1 A Pharma

Active Ingredient:
Memantine Hydrochloride
Origin:
EU

Memantin 1 A Pharma (Memantine Hydrochloride)

Memantine, the active ingredient in Memantin 1 A Pharma, is a NMDA receptor antagonist presented as a tablet for oral use. It is indicated for the treatment of moderate to severe Alzheimer’s disease in adults.
GNH India supplies Memantin 1 A Pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

1 A Pharma Gmbh

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Memantine is used in the treatment of Alzheimer’s disease, targeting the glutamatergic pathway associated with cognitive decline.

  • Moderate to severe Alzheimer’s disease: improves cognition and functional abilities in patients with established disease.
  • Cognitive impairment in Alzheimer’s disease: may help maintain daily living activities.
  • Functional decline in Alzheimer’s disease: supports slower progression of daily functional loss.

How It Works

  • Memantine acts as a non‑competitive antagonist at the NMDA (N‑methyl‑D‑aspartate) receptor. By binding to the receptor-associated ion channel with moderate affinity, it blocks excessive calcium influx caused by overstimulation of glutamate, thereby reducing excitotoxic neuronal injury while preserving normal synaptic transmission.

Side Effects

Common side effects are generally mild and may resolve with continued therapy.

Common Side Effects

  • Dizziness
  • Headache
  • Constipation
  • Confusion
  • Fatigue
  • Nausea

Serious or Rare Side Effects

  • Severe skin reactions such as Stevens‑Johnson syndrome
  • Hepatic dysfunction or elevated liver enzymes
  • Seizures
  • Suicidal thoughts or behavior
  • Neuroleptic malignant‑like syndrome
  • Persistent hallucinations or psychosis

Precautions & Warnings

Memantin 1 A Pharma requires careful patient assessment and monitoring.

  • Renal impairment: evaluate renal function and adjust dose if necessary.
  • Hepatic impairment: monitor liver enzymes during therapy.
  • History of seizures: use with caution and observe for increased seizure activity.
  • Concomitant NMDA antagonists: avoid combined use to reduce risk of neurotoxicity.
  • Pregnancy and lactation: safety not established; weigh potential benefits against risks.
  • Store at ambient temperature below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Memantin 1 A Pharma may interact with several medicines; awareness of interaction severity guides clinical decisions.

Major Interactions (Avoid)

  • Amantadine: additive NMDA antagonism may increase neurotoxicity.
  • Other NMDA antagonists (e.g., dextromethorphan): risk of excessive inhibition.
  • Strong alkaline antacids (e.g., magnesium hydroxide): may reduce memantine absorption.

Moderate Interactions (Monitor Closely)

  • CNS depressants (e.g., benzodiazepines): may enhance sedation.
  • Diuretics (e.g., furosemide): can raise plasma memantine concentrations.
  • Carbamazepine: may lower memantine levels, reducing efficacy.

Frequently Asked Questions

Memantin 1 A Pharma contains memantine, which is prescribed for the management of moderate to severe Alzheimer’s disease. It helps improve cognition, memory, and daily functioning in patients with established disease by modulating glutamatergic activity in the brain.

Memantine works as a non‑competitive antagonist of the NMDA receptor. By blocking excessive calcium entry through the receptor’s ion channel, it reduces excitotoxic neuronal damage while allowing normal synaptic transmission, thereby supporting neuronal health in Alzheimer’s disease.

The dosage of Memantin 1 A Pharma is individualized and set by the prescribing clinician based on the patient’s condition, renal function, and tolerability. Physicians typically start with a low dose and titrate upward, but exact regimens should only be provided by a qualified health professional.

Safety data for memantine during pregnancy and lactation are limited. The drug is not routinely recommended for pregnant or nursing women unless the potential benefit justifies the potential risk. Clinicians should discuss individual circumstances with the patient.

To order Memantin 1 A Pharma, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain needs), and import documentation.

Memantine belongs to the NMDA‑receptor antagonist class, whereas many other Alzheimer’s agents are cholinesterase inhibitors (e.g., donepezil, rivastigmine). Memantine is typically used in moderate to severe stages and may be combined with a cholinesterase inhibitor for additive benefit, while cholinesterase inhibitors are often started earlier in the disease course.

Store Memantin 1 A Pharma at ambient temperature below 25 °C. Keep the tablets in the original container, protect them from moisture and direct sunlight, and ensure the packaging remains tightly closed to maintain product stability.

Memantin 1 A Pharma is administered orally, with or without food. Tablets should be swallowed whole with a glass of water. The prescribing physician will determine the appropriate dosing schedule, which is usually once daily after a titration period.

Serious risks include severe skin reactions such as Stevens‑Johnson syndrome, hepatic dysfunction, seizures, and emergent suicidal thoughts or behaviors. Patients should seek immediate medical attention if they experience rash, jaundice, uncontrolled seizures, or significant mood changes.

Memantin 1 A Pharma should be avoided in patients with known hypersensitivity to memantine or any excipients, those with severe renal impairment without dose adjustment, and individuals taking other NMDA antagonists that could cause additive toxicity. Clinicians must evaluate each patient’s medical history before prescribing.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.