Product image of Memantin Stada (Memantine Hydrochloride) supplied by GNH India

Memantin Stada

Active Ingredient:
Memantine Hydrochloride
Origin:
EU

Memantin Stada (Memantine Hydrochloride)

Memantine Hydrochloride, the active ingredient in Memantin Stada, is a NMDA receptor antagonist presented as an oral tablet for oral use. It treats moderate to severe Alzheimer’s disease in adult patients.

GNH India supplies Memantin Stada as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Stada Arzneimittel Ag

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Indications & Clinical Uses

Memantin Stada, an NMDA receptor antagonist used in dementia care, is indicated for:

  • Alzheimer's disease (moderate to severe): Improves cognition and functional abilities in patients with moderate to severe disease.

How It Works

  • Memantine hydrochloride acts as a non‑competitive antagonist at the NMDA‑type glutamate receptor. By binding to the receptor-associated ion channel at a site distinct from the glutamate binding site, it reduces excessive calcium influx that occurs during pathological overstimulation. This modulation limits excitotoxic neuronal injury while preserving normal synaptic transmission, thereby helping to maintain neuronal function in patients with Alzheimer’s disease.

Side Effects

Memantin Stada may cause a range of adverse reactions. Monitoring and reporting of any new symptoms is recommended.

Common Side Effects

  • Dizziness
  • Headache
  • Constipation
  • Confusion
  • Fatigue

Serious or Rare Side Effects

  • Seizures
  • Severe allergic reactions (rash, angioedema)
  • Hallucinations or psychosis
  • Marked hypertension
  • Elevated liver enzymes

Precautions & Warnings

Before initiating therapy, consider the following precautions.

  • Renal impairment: dose may need adjustment in patients with reduced kidney function.
  • Hepatic disease: monitor liver function tests periodically.
  • History of seizures: use with caution as the drug may lower seizure threshold.
  • Concomitant use of other NMDA antagonists: increased risk of CNS effects.
  • Cardiovascular disease: monitor blood pressure regularly.
  • Store below 25°C: keep in the original container, protect from moisture.

Avoid Interactions

Memantin Stada can interact with other medicines; review patient medication lists carefully.

Major Interactions (Avoid)

  • Amantadine: combined NMDA antagonism may increase neuropsychiatric adverse effects.
  • High‑dose ketamine: additive CNS depression risk.

Moderate Interactions (Monitor Closely)

  • Anticholinergic agents: may worsen cognitive impairment.
  • CNS depressants (e.g., benzodiazepines): enhanced sedation.
  • Antihypertensives: possible additive blood pressure lowering.
  • Diuretics: monitor electrolyte balance.

Frequently Asked Questions

Memantin Stada is prescribed for the treatment of moderate to severe Alzheimer’s disease. It belongs to the class of NMDA receptor antagonists and is intended to help improve cognition, memory, and daily functioning in patients with this form of dementia.

Memantine hydrochloride works by binding to the NMDA‑type glutamate receptor at a site distinct from the glutamate binding site. This non‑competitive antagonism reduces excessive calcium influx during pathological overstimulation, limiting excitotoxic neuronal damage while preserving normal synaptic activity.

The dosage of Memantin Stada is determined by the prescribing clinician based on the patient’s clinical condition, renal function, and tolerability. The prescriber will select the appropriate strength and titration schedule according to current medical guidelines.

Safety data for Memantin Stada during pregnancy and lactation are limited, and the pregnancy category is listed as unknown. Healthcare providers must weigh potential benefits against possible risks before prescribing to pregnant or nursing women.

To order Memantin Stada, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Memantin Stada belongs to the NMDA antagonist class, whereas drugs such as donepezil, rivastigmine and galantamine are cholinesterase inhibitors. Memantine is typically used in moderate to severe disease and may be combined with a cholinesterase inhibitor for broader symptomatic coverage.

Memantin Stada tablets should be stored below 25 °C in their original packaging, protected from moisture and direct sunlight. Keep the product out of reach of children and avoid exposing it to excessive heat or humidity.

Memantin Stada is taken orally, usually as a tablet swallowed whole with water. It is commonly initiated at a low dose and titrated upward as directed by the prescriber to achieve the therapeutic target while monitoring tolerance.

Serious adverse events include seizures, severe allergic reactions such as rash or angioedema, hallucinations or psychosis, marked hypertension, and significant liver enzyme elevations. Patients should seek immediate medical attention if any of these symptoms develop.

Memantin Stada should be avoided in patients with known hypersensitivity to memantine or any excipients in the tablet. Caution is advised for individuals with uncontrolled seizures, severe renal impairment, or those taking other NMDA antagonists, as the risk of adverse CNS effects may be heightened.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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