Product image of Memantina Aurobindo (Memantine Hydrochloride) supplied by GNH India

Memantina Aurobindo

Active Ingredient:
Memantine Hydrochloride
Origin:
EU

Memantina Aurobindo (Memantine Hydrochloride)

Memantine Hydrochloride, the active ingredient in Memantina Aurobindo, is a NMDA receptor antagonist presented as an oral tablet for oral administration. It is indicated for the symptomatic treatment of moderate to severe Alzheimer’s disease, helping to improve cognition and daily functioning in adult patients.

GNH India supplies Memantina Aurobindo as a licensed, GDP‑compliant international pharmaceutical supplier, providing the product to hospitals, pharmacies and clinics worldwide, with distribution channels that meet EU regulatory standards and through ensuring consistent quality and traceability.

Manufacturer / TM Owner

Aurobindo Pharma (Italia) S.R.L.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Memantine Hydrochloride is an NMDA receptor antagonist used in the management of neurodegenerative disorders.
  • Alzheimer's disease: improves cognitive function and daily activities in patients with moderate to severe disease.

How It Works

  • Memantine Hydrochloride acts as a non‑competitive antagonist at the NMDA (N‑methyl‑D‑aspartate) receptor. By binding to the receptor-associated ion channel at a site distinct from the glutamate binding site, it reduces excessive calcium influx that occurs during excitotoxic neuronal activation, thereby helping to preserve neuronal integrity and function in the brain.

Side Effects

Common Side Effects

  • Dizziness
  • Headache
  • Constipation
  • Confusion
  • Somnolence

Serious or Rare Side Effects

  • Seizures
  • Cardiac arrhythmias
  • Severe skin reactions such as Stevens‑Johnson syndrome
  • Hepatic dysfunction
  • Acute hypertension

Precautions & Warnings

Memantine Hydrochloride requires careful consideration in several clinical situations.

  • Renal impairment: dose adjustment may be needed in patients with reduced kidney function.
  • Hepatic impairment: monitor liver enzymes and consider dose modification.
  • History of seizures: use with caution as the drug may lower seizure threshold.
  • Elderly patients: start at low dose and titrate slowly to reduce adverse events.
  • Concomitant NMDA agonists: avoid combined use due to potential antagonistic effects.
  • Store at ambient temperature: keep below 25°C, retain in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Memantine Hydrochloride can interact with several medicines that affect the NMDA pathway or central nervous system.

Major Interactions (Avoid)

  • Amantadine: additive NMDA antagonism may increase neurotoxicity.
  • Dextromethorphan: combined NMDA blockade can enhance central side effects.
  • Ketamine: concurrent use may intensify dissociative symptoms.
  • Other NMDA antagonists: risk of excessive inhibition of glutamatergic transmission.
  • High‑dose zinc supplements: may reduce memantine absorption.

Moderate Interactions (Monitor Closely)

  • NSAIDs: may increase risk of renal dysfunction.
  • Antihypertensives: monitor blood pressure as memantine can cause hypertension.
  • Anticholinergic agents: may worsen cognitive impairment.
  • SSRIs: observe for increased central nervous system effects.
  • Antiepileptic drugs: monitor seizure control closely.

Frequently Asked Questions

Memantina Aurobindo contains memantine hydrochloride, which is prescribed for the symptomatic treatment of moderate to severe Alzheimer’s disease. It helps to improve cognition, memory, and daily functional abilities in adult patients by modulating glutamatergic activity in the brain.

Memantine hydrochloride works as a non‑competitive antagonist of the NMDA receptor. By blocking excessive calcium influx through the receptor‑associated ion channel, it reduces excitotoxic neuronal damage that contributes to cognitive decline in Alzheimer’s disease.

The dosage of Memantina Aurobindo is determined by the prescribing clinician based on the patient’s condition, age, renal function, and other clinical factors. The prescriber will set the appropriate dose and titration schedule according to current medical guidelines.

Safety data for memantine in pregnancy and lactation are limited. The drug should only be used if the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and the necessary import documentation.

Memantine belongs to the NMDA receptor antagonist class, whereas other approved agents such as donepezil, rivastigmine, and galantamine are cholinesterase inhibitors. Memantine is typically used in moderate to severe disease and may be combined with a cholinesterase inhibitor for additive benefit, while the others are often started earlier in the disease course.

Memantina Aurobindo should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.

The medication is taken orally, usually once daily, with or without food as directed by the prescriber. Tablets should be swallowed whole with a glass of water and not crushed or chewed unless specifically instructed.

Serious adverse events, although rare, include seizures, cardiac arrhythmias, severe skin reactions such as Stevens‑Johnson syndrome, hepatic dysfunction, and acute hypertension. Patients should be monitored for any new or worsening symptoms and seek medical attention promptly if serious reactions occur.

Memantina Aurobindo is contraindicated in patients with known hypersensitivity to memantine or any of the excipients. Caution is advised for individuals with severe renal or hepatic impairment, a history of seizures, or those taking other NMDA antagonists, as these conditions may increase the risk of adverse effects.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.