Product image of Memantina Flas Normon (Memantine Hydrochloride) supplied by GNH India

Memantina Flas Normon

Active Ingredient:
Memantine Hydrochloride
Origin:
EU

Memantina Flas Normon (Memantine Hydrochloride)

Memantine Hydrochloride, the active ingredient in Memantina Flas Normon, is an NMDA receptor antagonist presented as an oral dosage form for oral use. It is indicated for the treatment of moderate to severe Alzheimer’s disease in adults, where it helps to reduce excitotoxic neuronal damage associated with disease progression.

GNH India supplies Memantina Flas Normon as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with established distribution networks and quality assurance processes that meet European Union standards.

Manufacturer / TM Owner

Laboratorios Normon, S.A.

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Indications & Clinical Uses

Memantina Flas Normon is an NMDA receptor antagonist used in the management of neurodegenerative dementia conditions.

  • Alzheimer’s disease (moderate to severe): improves cognition, global functioning and may slow disease progression in adult patients.

How It Works

  • Memantine Hydrochloride acts as a non‑competitive antagonist at the N‑methyl‑D‑aspartate (NMDA) receptor ion channel. By binding within the channel at moderate affinity, it blocks excessive calcium influx caused by overstimulation of glutamate, thereby reducing excitotoxic neuronal injury that contributes to cognitive decline in Alzheimer’s disease.

Side Effects

Memantina Flas Normon may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Dizziness: transient sensation of light‑headedness.
  • Headache: mild to moderate intensity.
  • Constipation: reduced bowel movements.
  • Confusion: temporary disorientation.

Serious or Rare Side Effects

  • Hallucinations: visual or auditory disturbances.
  • Seizures: rare occurrence of convulsive episodes.
  • Severe hypertension: marked increase in blood pressure requiring medical attention.

Precautions & Warnings

Before initiating therapy, clinicians should assess patient‑specific risk factors and monitor for potential complications.

  • Renal function: evaluate creatinine clearance and adjust if necessary.
  • History of seizures: use with caution and monitor neurologic status.
  • Cardiovascular disease: observe blood pressure and heart rate.
  • Concomitant NMDA antagonists: avoid additive neuro‑psychiatric effects.
  • Hepatic impairment: consider dose modification.
  • Store at below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Memantina Flas Normon can interact with other medicines that affect the central nervous system or NMDA pathways.

Major Interactions (Avoid)

  • Amantadine: additive NMDA antagonism may increase neuro‑psychiatric effects.
  • Ketamine: combined use can potentiate dissociative symptoms.
  • Other NMDA antagonists: risk of excessive CNS depression.

Moderate Interactions (Monitor Closely)

  • Diuretics: may raise plasma memantine concentrations.
  • Antihypertensives: potential for enhanced hypotensive response.
  • CNS depressants (e.g., benzodiazepines): may increase dizziness and sedation.

Frequently Asked Questions

Memantina Flas Normon contains memantine hydrochloride and is prescribed for adults with moderate to severe Alzheimer’s disease. It works by protecting neurons from excessive glutamate activity, which can help maintain cognitive function and daily living abilities.

Memantine hydrochloride is a non‑competitive antagonist of NMDA receptors. By blocking the receptor’s ion channel, it limits calcium overload caused by excessive glutamate, thereby reducing excitotoxic damage to brain cells that contributes to dementia progression.

The dosage of Memantina Flas Normon is determined by the prescribing clinician based on the patient’s clinical condition, renal function and tolerability. The prescriber will set the appropriate strength and dosing schedule.

Safety data for memantine in pregnancy and lactation are limited. The product should only be used if the potential benefit justifies any potential risk to the fetus or infant, and the decision must be made by a qualified healthcare professional.

To request Memantina Flas Normon, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Memantine belongs to the NMDA‑receptor antagonist class, whereas cholinesterase inhibitors (e.g., donepezil) increase acetylcholine levels. Memantine is typically used in moderate to severe stages, often in combination with a cholinesterase inhibitor, offering a complementary mechanism of neuroprotection.

Store Memantina Flas Normon at temperatures below 25 °C in its original container. Protect the product from moisture, excessive heat and direct sunlight to maintain stability and potency.

Memantina Flas Normon is taken orally, usually with or without food, as directed by the prescriber. The tablet should be swallowed whole with water and not crushed or chewed unless specifically advised.

Serious adverse events, although uncommon, include hallucinations, seizures and severe hypertension. Patients should be monitored for new or worsening neuro‑psychiatric symptoms and any sudden increase in blood pressure.

Memantina Flas Normon is contraindicated in patients with known hypersensitivity to memantine hydrochloride or any of the excipients. Caution is advised for individuals with uncontrolled seizures, severe renal impairment or those taking other NMDA antagonists.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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