Product image of Memantina Lanoratorio Stada, S.L. (Memantine) supplied by GNH India

Memantina Lanoratorio Stada, S.L.

Active Ingredient:
Memantine
Origin:
EU

Memantina Lanoratorio Stada, S.L. (Memantine)

Memantine, the active ingredient in Memantina Lanoratorio Stada, S.L., is a NMDA receptor antagonist presented as an oral formulation for oral use. It is indicated for the treatment of moderate to severe Alzheimer’s disease in adults.

GNH India supplies Memantina Lanoratorio Stada, S.L. as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratorio Stada, S.L.

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Indications & Clinical Uses

Memantine acts on the glutamatergic pathway and is used in the management of Alzheimer’s disease and related cognitive disorders.

  • Alzheimer’s disease (moderate to severe): helps improve cognition and daily functioning.
  • Dementia associated with Alzheimer’s disease: may slow progression of cognitive decline.
  • Behavioral disturbances in Alzheimer’s disease: can reduce agitation and aggression.

How It Works

  • Memantine is a non‑competitive antagonist of the NMDA (N‑methyl‑D‑aspartate) receptor. By binding to the receptor-associated ion channel at a site distinct from the glutamate binding site, it reduces excessive calcium influx caused by overstimulation, thereby decreasing excitotoxic neuronal damage while preserving normal synaptic transmission.

Side Effects

Memantine is generally well tolerated, but several adverse reactions have been reported.

Common Side Effects

  • Dizziness
  • Headache
  • Constipation
  • Confusion
  • Fatigue
  • Hypertension

Serious or Rare Side Effects

  • Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Seizures
  • Cardiac arrhythmias
  • Hepatic injury
  • Suicidal thoughts or behavior
  • Severe allergic reactions (anaphylaxis)

Precautions & Warnings

Memantine should be used with caution in specific patient populations and clinical situations.

  • Renal impairment: assess renal function before initiating therapy.
  • Hepatic impairment: monitor liver enzymes periodically.
  • Cardiovascular disease: observe for changes in blood pressure or heart rhythm.
  • History of seizures: evaluate seizure risk before treatment.
  • Concomitant use with other NMDA antagonists: avoid additive neurotoxicity.
  • Store below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Memantine may interact with several medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Amantadine: increased risk of neurotoxicity.
  • Ketamine: additive NMDA antagonism may cause profound CNS depression.
  • Other NMDA antagonists (e.g., dextromethorphan): heightened central nervous system effects.

Moderate Interactions (Monitor Closely)

  • Antihypertensives: possible enhancement of hypotensive effect.
  • Diuretics: may increase risk of dehydration and electrolyte imbalance.
  • CNS depressants (e.g., benzodiazepines): may amplify dizziness and sedation.

Frequently Asked Questions

Memantina Lanoratorio contains memantine, which is prescribed to treat moderate to severe Alzheimer’s disease. It helps improve cognitive function and daily activities by reducing excitotoxic neuronal damage associated with the disease.

Memantine works as a non‑competitive antagonist of the NMDA receptor. By blocking excessive calcium influx through the receptor’s ion channel, it limits glutamate‑induced excitotoxicity while allowing normal synaptic transmission, thereby protecting neurons in Alzheimer’s disease.

The appropriate dose of memantine is determined by the prescribing clinician based on the patient’s condition, age, renal function, and other factors. Dosage adjustments are individualized and should follow the prescriber’s instructions.

The safety of memantine in pregnancy and lactation has not been established. It is classified as pregnancy category unknown, and clinicians usually weigh potential benefits against risks before prescribing to pregnant or nursing women.

To place an order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and necessary import documentation.

Memantine belongs to the NMDA receptor antagonist class, whereas cholinesterase inhibitors such as donepezil act on acetylcholine metabolism. Memantine is typically used for moderate to severe stages, often in combination with a cholinesterase inhibitor, offering a complementary mechanism of neuroprotection.

Store the product below 25 °C in its original packaging, protecting it from moisture and direct sunlight. Ensure the container is tightly closed and keep it out of reach of children.

Memantina Lanoratorio is administered orally, usually as a tablet taken with or without food. The exact administration schedule should follow the prescriber’s directions.

Serious risks include severe skin reactions such as Stevens‑Johnson syndrome, seizures, cardiac arrhythmias, hepatic injury, and suicidal thoughts. Patients should seek immediate medical attention if they experience any of these symptoms.

Memantine is contraindicated in patients with known hypersensitivity to the drug or any of its excipients. Caution is advised for individuals with severe renal impairment, uncontrolled hypertension, or a history of seizures.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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