Product image of Memantina Stada (Memantine Hydrochloride) supplied by GNH India

Memantina Stada

Active Ingredient:
Memantine Hydrochloride
Origin:
EU

Memantina Stada (Memantine Hydrochloride)

Memantine hydrochloride, the active ingredient in Memantina Stada, is an NMDA receptor antagonist presented as an oral tablet for oral use. It is used to treat moderate to severe Alzheimer’s disease in adults and may help improve cognition, memory, and daily functioning.

GNH India supplies Memantina Stada as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company follows stringent quality standards and regulatory requirements across EU and global markets.

Manufacturer / TM Owner

Laboratorio Stada, S.L.

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Indications & Clinical Uses

Memantina Stada is an NMDA receptor antagonist indicated for the treatment of Alzheimer’s disease, a neurodegenerative disorder affecting cognition and function.

  • Alzheimer’s disease (moderate to severe): helps maintain cognitive abilities and daily activities in affected patients.

How It Works

  • Memantine hydrochloride acts as a non‑competitive antagonist at the N‑methyl‑D‑aspartate (NMDA) receptor. By binding to the receptor-associated ion channel, it reduces excessive calcium influx caused by glutamate over‑activation, thereby limiting excitotoxic neuronal injury and supporting neuronal survival in the brain.

Side Effects

Memantina Stada may cause a range of adverse reactions. Most are mild and reversible, but some can be serious and require medical attention.

Common Side Effects

  • Dizziness: sensation of light‑headedness or unsteadiness.
  • Headache: mild to moderate pain in the head region.
  • Constipation: reduced bowel movements or hard stools.
  • Confusion: transient difficulty concentrating or thinking clearly.

Serious or Rare Side Effects

  • Seizures: uncontrolled electrical activity in the brain.
  • Severe allergic reaction: rash, swelling, or difficulty breathing.
  • Cardiac arrhythmia: irregular heart rhythm that may require monitoring.

Precautions & Warnings

Before prescribing Memantina Stada, clinicians should consider several safety aspects.

  • Renal impairment: adjust dose or monitor renal function.
  • Hepatic impairment: use with caution in patients with liver disease.
  • History of seizures: evaluate risk of seizure exacerbation.
  • Cardiovascular disease: monitor blood pressure and heart rate.
  • Concomitant NMDA antagonists: avoid combined use due to additive effects.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Memantina Stada can interact with other medicines, altering its efficacy or safety profile.

Major Interactions (Avoid)

  • Amantadine: combined NMDA antagonism may increase neurotoxicity.
  • Ketamine: additive CNS effects and risk of severe dizziness.
  • Dextromethorphan: heightened risk of confusion and hallucinations.

Moderate Interactions (Monitor Closely)

  • CNS depressants (e.g., benzodiazepines): may enhance sedation.
  • Antihypertensives: possible additive blood‑pressure lowering.
  • Anticholinergic agents: may worsen cognitive side effects.
  • Other anti‑dementia drugs (e.g., donepezil): monitor for combined adverse effects.

Frequently Asked Questions

Memantina Stada contains memantine hydrochloride, an NMDA receptor antagonist indicated for the treatment of moderate to severe Alzheimer’s disease. It is prescribed to help maintain cognitive function and daily living activities in patients with this neurodegenerative condition.

Memantine hydrochloride blocks the NMDA‑type glutamate receptors in a non‑competitive manner. By reducing excessive calcium entry into neurons, it limits excitotoxic damage caused by over‑activation of glutamate pathways, thereby protecting brain cells and supporting neuronal function.

The dose of Memantina Stada is determined by the prescribing physician based on the patient’s clinical condition, renal function, and response to therapy. Dosage adjustments are made according to professional guidelines and individual patient needs.

The safety of memantine hydrochloride in pregnancy and lactation has not been definitively established. It should only be used if the potential benefit justifies any potential risk to the fetus or infant, and the decision must be made by a qualified healthcare professional.

To order Memantina Stada, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Memantina Stada (memantine) belongs to the NMDA‑receptor antagonist class, whereas drugs like donepezil or rivastigmine are acetylcholinesterase inhibitors. Memantine targets glutamate‑mediated excitotoxicity, offering a different mechanism that can be used alone or in combination with cholinergic agents for broader symptom control.

Memantina Stada should be stored at ambient temperature, below 25 °C, in its original packaging. Keep the product away from moisture, direct sunlight, and excessive heat to maintain its stability and potency throughout its shelf life.

Memantina Stada is taken orally, usually as a tablet, with or without food. The exact administration schedule—once daily or divided doses—depends on the prescriber’s instructions and the patient’s tolerance and therapeutic response.

Serious risks include seizures, severe allergic reactions (e.g., rash, swelling, breathing difficulty), and cardiac arrhythmias. Patients should be monitored for these events, and any sudden or severe symptoms should prompt immediate medical evaluation.

Memantina Stada is contraindicated in patients with known hypersensitivity to memantine hydrochloride or any of the tablet’s excipients. Caution is also advised for individuals with severe renal impairment, uncontrolled epilepsy, or those taking other NMDA‑antagonist medications.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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