Product image of Memantine Sandoz (Memantine Hydrochloride) supplied by GNH India

Memantine Sandoz

Active Ingredient:
Memantine Hydrochloride
Origin:
EU

Memantine Sandoz (Memantine Hydrochloride)

Memantine, the active ingredient in Memantine Sandoz, is a NMDA receptor antagonist presented as a tablet for oral use. It is used to treat cognitive symptoms of Alzheimer’s disease in adults.
GNH India supplies Memantine Sandoz as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Sandoz N.V.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Memantine acts on the glutamatergic pathway and is indicated for the treatment of Alzheimer’s disease.
  • Alzheimer's disease: helps improve cognition and functional abilities in patients with mild to moderate disease.

How It Works

  • Memantine hydrochloride binds to the NMDA (N‑methyl‑D‑aspartate) receptor at a site distinct from the glutamate binding site, acting as a non‑competitive antagonist. By reducing excessive calcium influx, it limits excitotoxic neuronal injury and helps preserve synaptic function in the brain.

Side Effects

Memantine is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Dizziness: sensation of light‑headedness or unsteadiness.
  • Headache: mild to moderate pain in the head region.
  • Constipation: reduced bowel movements or hard stools.
  • Confusion: transient disorientation or difficulty concentrating.
  • Hypertension: elevated blood pressure readings.
  • Somnolence: increased sleepiness or fatigue.

Serious or Rare Side Effects

  • Seizures: convulsive episodes requiring immediate medical attention.
  • Allergic reactions: rash, itching, swelling, or anaphylaxis.
  • Hallucinations: visual or auditory disturbances.
  • Cardiac arrhythmia: irregular heart rhythm.
  • Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.

Precautions & Warnings

  • Before initiating therapy, consider the following safety measures.
  • Renal impairment: adjust dose or monitor renal function.
  • Hepatic impairment: use with caution in patients with liver disease.
  • Concomitant NMDA antagonists: avoid combined use to reduce risk of additive CNS effects.
  • History of seizures: monitor closely for increased seizure activity.
  • Pregnancy and lactation: safety not established; weigh benefits against potential risks.
  • Store at below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Memantine may interact with other medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Amantadine: combined NMDA antagonism can increase neuropsychiatric side effects.
  • Cimetidine: may raise memantine plasma concentrations, enhancing toxicity.

Moderate Interactions (Monitor Closely)

  • CNS depressants (e.g., benzodiazepines, alcohol): may augment dizziness or somnolence.
  • Anticholinergic agents: could diminish therapeutic benefit on cognition.
  • Antihypertensive drugs: monitor blood pressure for additive hypotensive effects.

Frequently Asked Questions

Memantine Sandoz contains memantine hydrochloride and is prescribed to treat the cognitive symptoms of mild to moderate Alzheimer’s disease, helping to improve memory, thinking, and daily functioning.

Memantine acts as a non‑competitive antagonist at the NMDA receptor, reducing excessive calcium influx caused by glutamate over‑activation. This protects neurons from excitotoxic damage and supports synaptic activity.

The specific dose and titration schedule are determined by the prescribing clinician based on the patient’s condition, renal function, and tolerability. Patients should follow the prescriber’s instructions precisely.

Safety data for memantine in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by a healthcare professional.

Submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and import documentation.

Memantine belongs to the NMDA‑receptor antagonist class, whereas drugs like donepezil are acetylcholinesterase inhibitors. Memantine is typically used for moderate disease and may be combined with an acetylcholinesterase inhibitor for additive benefit.

Store the tablets at temperatures below 25 °C, in the original container, protected from moisture and direct sunlight. Keep out of reach of children and do not use after the expiry date.

Memantine Sandoz is taken orally, usually once daily after a gradual titration period. Tablets should be swallowed whole with water and not crushed or chewed unless otherwise directed by a healthcare professional.

Serious risks include seizures, severe allergic reactions such as anaphylaxis, hallucinations, and cardiac arrhythmias. Patients should seek immediate medical attention if any of these symptoms occur.

Memantine is contraindicated in patients with known hypersensitivity to memantine or any component of the formulation, and it should be used with caution in individuals with severe renal impairment or uncontrolled epilepsy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Memantine Hydrochloride

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT