Product image of Menofem (Dry Extract From Cimicifuga Racemosa (L.) Nutt., Rhizoma (Black Cohosh) (5-10:1), Extraction Solvent) supplied by GNH India

Menofem

Active Ingredient:
Dry Extract From Cimicifuga Racemosa (L.) Nutt., Rhizoma (Black Cohosh) (5-10:1), Extraction Solvent
Origin:
EU

Menofem (Dry Extract From Cimicifuga Racemosa (L.) Nutt., Rhizoma (Black Cohosh) (5-10:1), Extraction Solvent)

Cimicifuga racemosa (black cohosh) dry extract, the active ingredient in Menofem, is a herbal botanical presented as a dry extract for oral use. It is intended to help adult women manage common menopausal symptoms, including hot flashes, night sweats, and occasional mood changes.

GNH India supplies Menofem as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable sourcing for global healthcare providers through established distribution networks and regulatory support.

Manufacturer / TM Owner

Bionorica Se

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Indications & Clinical Uses

Menofem, a black cohosh dry extract, is used to alleviate symptoms associated with the menopausal transition.

  • Hot flashes: reduction in frequency and intensity of sudden warmth episodes.
  • Night sweats: decrease in the number and volume of nocturnal perspiration episodes.
  • Mood swings: improvement in emotional stability and reduction of irritability.

How It Works

  • The exact mechanism of Cimicifuga racemosa dry extract is not fully defined. It is thought to exert modulatory effects on serotonergic pathways and may influence estrogen receptor activity, leading to a reduction in vasomotor symptoms and associated discomfort during menopause.

Side Effects

Menofem is generally well tolerated, but some users may experience adverse reactions.

Common Side Effects

  • Mild gastrointestinal upset, such as nausea or stomach discomfort.
  • Headache or light‑headedness.
  • Dizziness, especially when standing quickly.
  • Skin rash or mild itching.

Serious or Rare Side Effects

  • Liver injury presenting as jaundice or elevated enzymes.
  • Severe allergic reaction, including swelling of the face or throat.
  • Unexplained bleeding or bruising.

Precautions & Warnings

Menofem should be used with awareness of the following precautions.

  • Pregnancy: safety not established; avoid use during pregnancy.
  • Breastfeeding: caution advised as transfer to milk is unknown.
  • Known allergy to black cohosh: discontinue use immediately.
  • Concurrent hormone therapy: monitor for additive estrogenic effects.
  • Pre‑existing liver disease: use only under medical supervision.
  • Store at ambient temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Potential drug interactions with Menofem should be considered.

Major Interactions (Avoid)

  • Hormone replacement therapy: may increase overall estrogenic activity.
  • Anticoagulants (e.g., warfarin): possible heightened bleeding risk.

Moderate Interactions (Monitor Closely)

  • Selective serotonin reuptake inhibitors (SSRIs): potential serotonergic interaction.
  • Antihypertensive agents: may affect blood pressure control.
  • CYP450 substrate drugs: possible alteration of metabolism leading to changed plasma levels.

Frequently Asked Questions

Menofem is an oral herbal product containing a dry extract of Cimicifuga racemosa (black cohosh). It is used to help adult women manage common menopausal symptoms such as hot flashes, night sweats, and occasional mood changes.

The exact mechanism is not fully understood. The extract is believed to influence serotonergic pathways and may modulate estrogen receptor activity, which together help reduce vasomotor symptoms associated with menopause.

The appropriate dose of Menofem is determined by a qualified healthcare professional based on individual needs and local guidelines. Patients should follow the prescriber’s instructions and not alter the dose without medical advice.

Safety of Menofem in pregnancy has not been established, and it is generally advised to avoid use while pregnant. For breastfeeding women, caution is recommended because transfer to breast milk is unknown; consult a healthcare provider.

To order Menofem, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Menofem is a botanical option that differs from hormone replacement therapy (HRT) by not containing hormones. While HRT directly replaces estrogen, Menofem’s black cohosh extract may act through serotonergic and estrogen‑modulating pathways, offering a non‑hormonal alternative for symptom relief.

Menofem should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.

Menofem is taken orally as directed by a healthcare professional. The tablet or capsule is swallowed with water, typically with or without food, according to the prescriber’s recommendation.

Serious risks, although rare, include liver injury and severe allergic reactions such as swelling of the face, throat or tongue. Users should seek immediate medical attention if they notice signs of jaundice, rash, or difficulty breathing.

Menofem should be avoided by individuals with known hypersensitivity to black cohosh, pregnant women, and those with severe liver disease unless specifically advised by a physician. It is also not recommended for patients taking certain hormone therapies or anticoagulants without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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