Product image of Menopur (Menotrophin) supplied by GNH India

Menopur

Active Ingredient:
Menotrophin
Origin:
EU

Menopur (Menotrophin)

Menotropin, the active ingredient in Menopur, is a gonadotropin presented as a solution for injection (powder for solution) for intramuscular and subcutaneous use. It treats infertility due to anovulation and is used in assisted reproductive technologies in women.

GNH India supplies Menopur as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Ferring N.V.

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Indications & Clinical Uses

Menopur is a gonadotropin used in fertility treatment and related endocrine disorders.

  • Anovulatory infertility: induces follicular development to enable ovulation.
  • Controlled ovarian stimulation for IVF: supports multiple follicle growth for egg retrieval.
  • Hypogonadotropic hypogonadism: provides FSH and LH activity to restore normal ovarian function.

How It Works

  • Menotropin contains both follicle‑stimulating hormone (FSH) and luteinising hormone (LH) activity. It binds to FSH receptors on granulosa cells and LH receptors on theca cells, stimulating ovarian follicular growth, estrogen synthesis, and ultimately ovulation, thereby facilitating assisted reproductive procedures.

Side Effects

Menopur may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Injection site pain or erythema.
  • Mild ovarian hyperstimulation syndrome (OHSS).
  • Abdominal bloating or discomfort.
  • Headache.
  • Nausea.

Serious or Rare Side Effects

  • Severe ovarian hyperstimulation syndrome.
  • Thromboembolic events.
  • Allergic reactions including anaphylaxis.

Precautions & Warnings

Before using Menopur, several safety considerations should be observed.

  • Patient selection: assess ovarian reserve and baseline hormone levels.
  • Monitoring: perform regular ultrasound and estradiol measurements to detect OHSS early.
  • Contraindications: avoid in confirmed pregnancy, uncontrolled thyroid disease, or active ovarian cysts.
  • Drug interactions: review concomitant hormonal therapies for potential effects.
  • Pregnancy: discontinue treatment if pregnancy is confirmed.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Menopur can interact with other medications, requiring careful management.

Major Interactions (Avoid)

  • GnRH agonists or antagonists: may increase risk of ovarian hyperstimulation.
  • Estrogen‑containing oral contraceptives: can blunt ovarian response if not discontinued.
  • Thyroid hormone therapy: may necessitate adjustment of Menopur dosing.

Moderate Interactions (Monitor Closely)

  • Anticoagulants: monitor for bleeding complications if ovarian cysts rupture.
  • Insulin or oral hypoglycemics: watch glucose control during OHSS episodes.

Frequently Asked Questions

Menopur is a gonadotropin preparation used to treat infertility caused by anovulation, to support controlled ovarian stimulation in assisted reproductive technologies such as in‑vitro fertilisation, and to manage hypogonadotropic hypogonadism by providing both FSH and LH activity.

Menotropin contains follicle‑stimulating hormone (FSH) and luteinising hormone (LH) activity. It binds to FSH receptors on ovarian granulosa cells and LH receptors on theca cells, promoting follicular growth, estrogen production, and ultimately triggering ovulation, which is essential for fertility treatments.

The dose of Menopur is individualized. A qualified prescriber determines the amount, frequency and duration based on the patient’s ovarian reserve, treatment protocol and response to monitoring, ensuring optimal efficacy and safety.

Menopur is not intended for use during an established pregnancy and should be discontinued if pregnancy occurs. Safety data for breastfeeding are limited; therefore, the medication is generally avoided while nursing unless the prescriber decides the benefits outweigh potential risks.

To order Menopur, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain where required) and necessary import documentation.

Menopur provides a combined FSH and LH activity in a single preparation, which can simplify dosing compared with separate FSH‑only products. Some clinicians prefer Menopur for patients needing both hormones, while others may choose recombinant FSH alone for more precise dose titration. The choice depends on individual patient characteristics and protocol preferences.

Menopur should be stored refrigerated at 2‑8 °C, protected from light, and must not be frozen or shaken. Keep the vial in its original packaging until use, and discard any solution that appears discoloured or contains particles.

Menopur is supplied as a powder for solution that is reconstituted with sterile water. The resulting solution is injected either intramuscularly or subcutaneously, following the prescriber’s instructions regarding injection site, technique and timing relative to other medications.

The most serious risks include severe ovarian hyperstimulation syndrome (OHSS), which can lead to fluid accumulation, thromboembolic events, and, in rare cases, anaphylactic reactions. Prompt medical attention is required if symptoms such as rapid weight gain, severe abdominal pain, shortness of breath or allergic signs develop.

Menopur is contraindicated in women who are already pregnant, have active ovarian cysts, uncontrolled thyroid disease, severe ovarian hyperstimulation syndrome, or known hypersensitivity to any component of the product. It should also be used with caution in patients with a history of thromboembolic disorders.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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