Product image of Menopur (Menotrophin) supplied by GNH India

Menopur

Active Ingredient:
Menotrophin
Origin:
EU

Menopur (Menotrophin)

Menotrophin, the active ingredient in Menopur, is a gonadotropin presented as an injectable solution for subcutaneous use. It treats infertility caused by anovulation and is employed in assisted reproductive technologies such as in‑vitro fertilisation.

GNH India supplies Menopur as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, fertility clinics and pharmacies worldwide.

Manufacturer / TM Owner

Ferring Gmbh

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Indications & Clinical Uses

Menopur is a gonadotropin used to stimulate ovarian function in various infertility contexts.

  • Infertility due to anovulation: promotes follicular development to enable ovulation.
  • Assisted reproductive technology (IVF): supports controlled ovarian stimulation for egg retrieval.
  • Intrauterine insemination (IUI): enhances follicular growth to improve timing and success of insemination.

How It Works

  • Menotrophin contains both follicle‑stimulating hormone (FSH) and luteinising hormone (LH) activity. After subcutaneous injection it binds to FSH and LH receptors on ovarian granulosa and theca cells, stimulating folliculogenesis, estradiol production and final maturation of the dominant follicle, thereby facilitating ovulation.

Side Effects

Menopur may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Injection site pain: mild discomfort at the injection site.
  • Abdominal bloating: feeling of fullness or mild distension.
  • Headache: occasional mild to moderate headache.
  • Nausea: transient feeling of queasiness.

Serious or Rare Side Effects

  • Ovarian hyperstimulation syndrome: severe swelling and fluid shift.
  • Multiple pregnancy: increased chance of twins or higher order gestations.
  • Severe allergic reaction: rash, swelling, or anaphylaxis.

Precautions & Warnings

Menopur requires careful clinical monitoring to minimise risks.

  • Monitor ovarian response: regular ultrasound and hormone checks.
  • Assess contraindications: avoid in patients with ovarian cysts or active malignancy.
  • Avoid use with uncontrolled thyroid disease: thyroid status can affect response.
  • Use caution in patients with a history of thromboembolism: increased clotting risk.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Menopur can interact with other hormonal agents and medications affecting coagulation.

Major Interactions (Avoid)

  • Estrogen‑containing contraceptives: may reduce gonadotropin efficacy.
  • Concurrent use of other gonadotropins: heightens risk of ovarian hyperstimulation.
  • Anticoagulants: may increase bleeding at injection sites.

Moderate Interactions (Monitor Closely)

  • Corticosteroids: can alter ovarian response.
  • Thyroid hormone therapy: may affect stimulation outcomes.
  • Antipsychotics that raise prolactin: could modify treatment effectiveness.

Frequently Asked Questions

Menopur is used to treat infertility caused by anovulation and to support ovarian stimulation in assisted reproductive technologies such as in‑vitro fertilisation and intrauterine insemination. It helps develop mature follicles that can be retrieved for fertilisation.

Menotrophin contains both FSH and LH activity. After subcutaneous injection it binds to FSH and LH receptors on ovarian cells, stimulating follicle growth, estrogen production and final maturation of the dominant follicle, which leads to ovulation.

The dose of Menopur is individualized. The prescribing clinician determines the amount and schedule based on the patient’s ovarian response, treatment protocol and monitoring results. No fixed regimen can be provided without a medical prescription.

Menopur is intended for use before conception to achieve pregnancy. Its safety in an established pregnancy or while breastfeeding has not been established, and it should only be used under specialist supervision in the context of fertility treatment.

To order Menopur, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain handling) and necessary import documentation.

Menopur provides combined FSH and LH activity in a single preparation, which can simplify dosing compared with separate FSH‑only products. Clinicians may choose it for patients who benefit from LH supplementation, while other gonadotropins may be preferred when only FSH activity is required.

Menopur must be stored refrigerated at 2‑8 °C, protected from light, and must not be frozen or shaken. Before use, allow the vial to reach room temperature if required, and handle with aseptic technique to maintain sterility.

Menopur is given as a subcutaneous injection, typically into the abdomen or thigh. The injection is performed by a trained healthcare professional or a patient who has been instructed in proper aseptic technique and dosing.

The most serious risks include ovarian hyperstimulation syndrome, which can be severe and require hospitalization, multiple pregnancy, and rare severe allergic reactions. Patients are monitored closely with ultrasound and hormone measurements to detect these complications early.

Menopur should not be used in individuals with known hypersensitivity to menotropin, active ovarian cysts, uncontrolled thyroid disease, or those who are pregnant. It is also contraindicated in patients with certain hormone‑dependent cancers or severe uncontrolled medical conditions.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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