Product image of Menotrophin Ferring-Léčiva (Menotrophin) supplied by GNH India

Menotrophin Ferring-Léčiva

Active Ingredient:
Menotrophin
Origin:
EU

Menotrophin Ferring-Léčiva (Menotrophin)

Menotrophin, the active ingredient in Menotrophin Ferring-Léčiva, is a gonadotropin presented as a sterile solution for subcutaneous use. It is employed to treat infertility caused by anovulation, to induce ovulation, and to support controlled ovarian hyperstimulation in assisted reproductive protocols. GNH India supplies Menotrophin Ferring-Léčiva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable cold‑chain logistics for biologic products. Clients benefit from responsive technical support and regulatory expertise across EU and global markets.

Manufacturer / TM Owner

Ferring Léciva A.S.

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Indications & Clinical Uses

  • Menotrophin is used in reproductive medicine to stimulate follicular development and ovulation.
  • Infertility due to anovulation: helps restore regular ovulation and improve chances of conception.
  • Induction of ovulation: used in timed intercourse or intra‑uterine insemination cycles to trigger ovulation.
  • Controlled ovarian hyperstimulation: combined with other agents in in‑vitro fertilisation protocols to produce multiple mature follicles.

How It Works

  • Menotrophin contains purified human follicle‑stimulating hormone (FSH) and luteinizing hormone (LH) in a fixed ratio. After subcutaneous injection, the FSH component binds to FSH receptors on ovarian granulosa cells, promoting follicular growth, while the LH component activates LH receptors on theca cells, supporting steroidogenesis and final follicle maturation. The combined activity mimics the natural pituitary surge, leading to follicular development and ovulation.

Side Effects

Menotrophin may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Abdominal discomfort
  • Injection site pain or erythema
  • Headache
  • Mild ovarian hyperstimulation (e.g., bloating, mild abdominal distension)

Serious or Rare Side Effects

  • Ovarian hyperstimulation syndrome (severe)
  • Multiple pregnancy
  • Allergic reaction or anaphylaxis
  • Thromboembolic events

Precautions & Warnings

  • When using Menotrophin, clinicians should observe several precautionary measures to ensure patient safety.
  • Pregnancy testing: confirm patient is not pregnant before initiating therapy.
  • Ovarian monitoring: perform regular ultrasound to assess follicular response.
  • Thromboembolic risk: evaluate history of clotting disorders.
  • Allergy: assess for hypersensitivity to menotropins or excipients.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Menotrophin can interact with other medications that influence hormonal pathways or coagulation.

Major Interactions (Avoid)

  • GnRH agonists: may amplify ovarian response and increase risk of severe hyperstimulation.
  • Oral contraceptives: suppress endogenous gonadotropins, reducing Menotrophin efficacy.
  • Anticoagulants: heightened bleeding risk if ovarian cysts rupture.

Moderate Interactions (Monitor Closely)

  • Thyroid hormone therapy: may alter ovarian responsiveness; monitor thyroid status.
  • Corticosteroids: can affect hormone metabolism; adjust dosing if needed.

Frequently Asked Questions

Menotrophin Ferring-Léčiva is a gonadotropin preparation used in assisted reproductive technology to treat infertility caused by anovulation, to induce ovulation for timed intercourse or intra‑uterine insemination, and to support controlled ovarian hyperstimulation in in‑vitro fertilisation cycles.

The product provides exogenous follicle‑stimulating hormone (FSH) and luteinizing hormone (LH) activity. FSH promotes growth of ovarian follicles, while LH supports steroid production and final maturation, together mimicking the natural pituitary surge that leads to ovulation.

The dose of Menotrophin is individualized. A qualified prescriber determines the amount, frequency and duration based on the patient’s ovarian response, treatment protocol and clinical goals. No fixed regimen is provided in public information.

Menotrophin is intended for use before conception and is not indicated for treatment during pregnancy. Safety data for use while breastfeeding are lacking, so the product should be avoided in nursing mothers unless the prescriber decides the benefits outweigh potential risks.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain logistics) and any necessary import documentation.

Menotrophin contains a fixed combination of FSH and LH, whereas some alternatives provide only FSH (e.g., recombinant FSH) or separate LH preparations. The combined formulation can simplify dosing for protocols that require both hormones, but clinicians may choose other products based on specific patient characteristics, cost or regulatory considerations.

Menotrophin must be stored refrigerated at 2‑8 °C. Keep the vial in its original packaging, protect it from light, and avoid freezing or shaking. If the product reaches room temperature for a short period during administration, it may be used, but it should be returned to refrigeration promptly.

Menotrophin is given by subcutaneous injection, typically into the abdomen or thigh. The injection is performed by a trained healthcare professional or a patient who has been instructed on proper aseptic technique and dose preparation.

The most serious risks include severe ovarian hyperstimulation syndrome, which can cause fluid accumulation, thrombosis, and organ dysfunction, as well as the possibility of multiple pregnancy and rare allergic reactions such as anaphylaxis. Prompt medical attention is required if these events are suspected.

Menotrophin is contraindicated in patients with known hypersensitivity to menotropins or any excipients, in those with active ovarian cysts, uncontrolled thyroid disease, or a history of severe ovarian hyperstimulation syndrome. It should also be avoided in pregnant women and is not recommended for use in patients with uncontrolled endocrine disorders without specialist supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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