Product image of Menotrophin Ferring (Menotrophin) supplied by GNH India

Menotrophin Ferring

Active Ingredient:
Menotrophin
Origin:
EU

Menotrophin Ferring (Menotrophin)

Menotrophin, the active ingredient in Menotrophin Ferring, is a gonadotropin presented as an injectable solution for intramuscular and subcutaneous use. It treats infertility related to anovulation and supports ovarian stimulation in assisted reproductive technologies.

GNH India supplies Menotrophin Ferring as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, fertility clinics and pharmacies worldwide.

Manufacturer / TM Owner

Ferring N.V.

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Indications & Clinical Uses

  • Menotrophin acts on the reproductive hormone axis to address several infertility‑related conditions.
  • Infertility due to anovulation: stimulates follicular growth to enable ovulation in women who do not ovulate spontaneously.
  • Controlled ovarian stimulation for assisted reproductive technology (e.g., IVF): provides FSH/LH activity to develop multiple follicles for egg retrieval.
  • Induction of ovulation in hypogonadotropic hypogonadism: replaces deficient gonadotropins to trigger ovulation in women with low endogenous FSH/LH.

How It Works

  • Menotrophin contains both follicle‑stimulating hormone (FSH) and luteinizing hormone (LH) analogues. After subcutaneous or intramuscular injection, the FSH component binds to ovarian FSH receptors, promoting granulosa cell proliferation and estrogen synthesis, while the LH component activates theca cells and supports luteinization. The combined activity enhances follicular development and triggers ovulation, facilitating assisted reproductive procedures.

Side Effects

Menotrophin may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Injection site pain or erythema
  • Mild abdominal discomfort or bloating
  • Headache
  • Nausea or mild vomiting
  • Transient ovarian hyperstimulation (mild)
  • Fatigue

Serious or Rare Side Effects

  • Severe ovarian hyperstimulation syndrome (OHSS)
  • Multiple pregnancy
  • Allergic reaction or anaphylaxis
  • Thromboembolic events
  • Severe abdominal pain or ascites
  • Visual disturbances or blurred vision

Precautions & Warnings

  • When using Menotrophin, clinicians should observe several safety measures.
  • Monitor ovarian response: use ultrasound and estradiol levels to adjust dose.
  • Avoid in active ovarian cysts: risk of rupture or exacerbated symptoms.
  • Assess for hypersensitivity: discontinue if severe allergic reaction occurs.
  • Use caution in patients with thromboembolic risk: monitor for signs of clot formation.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Menotrophin can interact with other medications that affect hormonal balance or clotting.

Major Interactions (Avoid)

  • GnRH agonists: may amplify ovarian response, increasing OHSS risk.
  • Oral contraceptives: suppress endogenous gonadotropins, reducing efficacy.
  • Medications that raise estrogen levels: may heighten OHSS risk.

Moderate Interactions (Monitor Closely)

  • Anticoagulants: monitor for thrombotic events.
  • Diabetes medications: monitor glucose if OHSS develops.
  • Corticosteroids: may affect hormone metabolism and response.

Frequently Asked Questions

Menotrophin is used to treat infertility caused by anovulation, to stimulate ovarian follicle development for assisted reproductive technologies such as in‑vitro fertilisation, and to induce ovulation in women with hypogonadotropic hypogonadism.

Menotrophin provides exogenous follicle‑stimulating hormone (FSH) and luteinizing hormone (LH) activity. FSH promotes growth of ovarian follicles and estrogen production, while LH supports theca cell function and final maturation of the follicle, together enabling ovulation.

The dose of Menotrophin is individualized. A qualified prescriber determines the amount, frequency and duration of treatment based on the patient’s ovarian response, the specific assisted reproductive protocol and other clinical factors.

Menotrophin is intended for use before pregnancy to achieve ovulation. Its safety in established pregnancy or while breastfeeding has not been established, and it should only be used under specialist supervision in the pre‑conception phase.

To order Menotrophin, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain where required) and necessary import documentation.

Menotrophin contains both FSH and LH activity in a single preparation, whereas some alternatives provide only FSH (e.g., recombinant FSH) and require separate LH supplementation. This combined formulation can simplify dosing schedules but may be less flexible for patients who need individualized FSH/LH ratios.

Menotrophin should be stored refrigerated at 2‑8 °C, protected from light, and must not be frozen or shaken. The vial should remain in its original packaging until use to maintain stability.

Menotrophin is supplied as an injectable solution for subcutaneous or intramuscular injection. The injection is typically performed by a trained healthcare professional or a patient after proper instruction, following aseptic technique.

The most serious risks include severe ovarian hyperstimulation syndrome (OHSS), which can cause abdominal pain, fluid accumulation and thromboembolic complications, as well as the possibility of multiple pregnancy and rare allergic reactions.

Menotrophin is contraindicated in individuals with known hypersensitivity to any component of the product, active ovarian cysts, uncontrolled thyroid disease, or those at high risk for thromboembolic events without appropriate monitoring.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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