Product image of Mensinorm Set (Follicle-Stimulating Hormone, Luteinising Hormone) supplied by GNH India

Mensinorm Set

Active Ingredient:
Follicle-Stimulating Hormone, Luteinising Hormone
Origin:
EU

Mensinorm Set (Follicle-Stimulating Hormone, Luteinising Hormone)

Follicle-Stimulating Hormone; Luteinising Hormone, the active ingredient in Mensinorm Set, is a gonadotropin presented as an injectable solution for subcutaneous use. It is used to treat infertility related to anovulation, to support controlled ovarian stimulation in assisted reproductive technology, and to manage hypogonadotropic hypogonadism.

GNH India supplies Mensinorm Set as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality and regulatory compliance.

Manufacturer / TM Owner

Ibsa Farmaceutici Italia

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Indications & Clinical Uses

  • Mensinorm Set, a gonadotropin preparation, is employed in reproductive medicine to stimulate ovarian function.
  • Infertility due to anovulation: promotes follicular growth to enable ovulation.
  • Controlled ovarian stimulation for assisted reproductive technology: enhances multiple follicle development for IVF cycles.
  • Hypogonadotropic hypogonadism: replaces deficient gonadotropins to restore normal ovarian activity.

How It Works

  • Follicle‑Stimulating Hormone (FSH) and Luteinising Hormone (LH) in Mensinorm Set bind to their respective receptors on ovarian granulosa and theca cells. Activation of FSH receptors stimulates follicular recruitment, growth, and estradiol synthesis, while LH receptor activation supports theca cell androgen production and final follicular maturation, culminating in ovulation when appropriate hormonal cues are present.

Side Effects

Adverse reactions to Mensinorm Set are reported primarily at the injection site and systemically.

Common Side Effects

  • Injection site pain or erythema
  • Mild abdominal discomfort or bloating
  • Nausea or mild headache
  • Transient ovarian hyperstimulation (mild)
  • Fatigue or dizziness

Serious or Rare Side Effects

  • Severe ovarian hyperstimulation syndrome (OHSS)
  • Multiple pregnancy (high-order twins or more)
  • Allergic reaction including anaphylaxis
  • Thromboembolic events (deep vein thrombosis, pulmonary embolism)
  • Ectopic pregnancy

Precautions & Warnings

  • When using Mensinorm Set, clinicians should observe several safety measures.
  • Assess ovarian response before initiation: perform baseline ultrasound and hormone levels.
  • Monitor estradiol concentrations: adjust dose to avoid excessive stimulation.
  • Avoid use in uncontrolled thyroid or adrenal disorders: stabilize endocrine status first.
  • Exercise caution in patients with ovarian cysts or polycystic ovary syndrome: risk of OHSS may be higher.
  • Discontinue if hypersensitivity reaction occurs: stop treatment and provide appropriate care.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Mensinorm Set may interact with other agents that influence ovarian activity or coagulation.

Major Interactions (Avoid)

  • Concurrent use of other gonadotropins (e.g., hCG) that markedly increase OHSS risk.
  • High‑dose estrogen therapy: may exacerbate ovarian hyperstimulation.
  • Anticoagulants in patients predisposed to thrombosis: increased clotting risk.

Moderate Interactions (Monitor Closely)

  • GnRH agonists or antagonists used in IVF protocols: require dose adjustment.
  • Corticosteroids that alter hormone metabolism: monitor estradiol levels.
  • Thyroid hormone replacement: ensure euthyroid status before stimulation.

Frequently Asked Questions

Mensinorm Set is a gonadotropin preparation containing FSH and LH that is used to treat infertility caused by anovulation, to support controlled ovarian stimulation in assisted reproductive technology such as IVF, and to replace deficient gonadotropins in patients with hypogonadotropic hypogonadism.

FSH binds to receptors on ovarian granulosa cells, stimulating follicle recruitment, growth, and estradiol production. LH binds to receptors on theca cells and mature follicles, promoting androgen synthesis and final maturation, which together enable ovulation when the hormonal environment is appropriate.

The dose of Mensinorm Set is individualized. A qualified prescriber determines the amount, frequency, and duration of treatment based on the patient’s ovarian response, hormone levels, and the specific clinical protocol being followed.

Mensinorm Set is not intended for use during an established pregnancy, and its safety in breastfeeding women has not been established. It should only be used under medical supervision in the pre‑conception or early treatment phases as directed by a fertility specialist.

To order Mensinorm Set, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain logistics if needed) and any required import documentation.

Mensinorm Set combines both FSH and LH in a single injectable formulation, which can simplify dosing compared with regimens that require separate FSH and LH preparations. Clinical efficacy is comparable to other recombinant or purified gonadotropin products, while the choice often depends on physician preference, patient response, and cost considerations.

Mensinorm Set must be stored at 2‑8 °C (refrigerated). Keep the vial in its original packaging, protect it from light, and avoid freezing or shaking. Before use, allow the product to reach room temperature if required, and inspect for particulate matter or discoloration.

Mensinorm Set is administered by subcutaneous injection, typically into the abdominal wall or thigh. The injection is performed by a trained healthcare professional or a patient who has been instructed in aseptic technique and proper dosing, following the prescriber’s specific regimen.

The most serious risks include severe ovarian hyperstimulation syndrome (OHSS), which can cause abdominal pain, rapid weight gain, and fluid accumulation, as well as the possibility of multiple pregnancy, allergic reactions such as anaphylaxis, and rare thromboembolic events. Prompt medical attention is required if any of these occur.

Mensinorm Set should not be used in individuals with known hypersensitivity to any component of the product, in patients with uncontrolled thyroid or adrenal disorders, in those with active ovarian cysts that could increase OHSS risk, or in women who are already pregnant. Contra‑indications are determined by the treating physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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