Product image of Menveo (Meningococcal Group Y Oligosaccharide Conjugated To Corynebacterium Diphtheriae Crm197 Protein, N. M) supplied by GNH India

Menveo

Active Ingredient:
Meningococcal Group Y Oligosaccharide Conjugated To Corynebacterium Diphtheriae Crm197 Protein, N. M
Origin:
EU

Menveo (Meningococcal Group Y Oligosaccharide Conjugated To Corynebacterium Diphtheriae Crm197 Protein, N. M)

Meningococcal Group Y Oligosaccharide Conjugated To Corynebacterium Diphtheriae Crm197 Protein, N. M, the active ingredient in Menveo, is a vaccine presented as an injectable solution for intramuscular use. It induces immunity against invasive disease caused by Neisseria meningitidis serogroups A, C, W-135 and Y in individuals at risk, including adolescents, travelers and those in high‑density living settings.

GNH India supplies Menveo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Gsk Vaccines S.R.L.

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Indications & Clinical Uses

Menveo is a conjugate vaccine that targets meningococcal polysaccharide antigens to prevent invasive meningococcal disease.

  • Individuals aged 2 months to 55 years: induces protective antibodies against serogroups A, C, W‑135 and Y.
  • Travelers to endemic regions: reduces the risk of meningococcal infection during travel.
  • College students living in dormitories: provides protection in high‑density residential settings.

How It Works

  • Menveo contains polysaccharide antigens from Neisseria meningitidis serogroups A, C, W‑135 and Y covalently linked to the CRM197 protein carrier. The conjugation enables a T‑cell‑dependent immune response, stimulating B‑cell maturation and the production of high‑affinity, long‑lasting protective antibodies against the meningococcal capsular polysaccharides.

Side Effects

Common Side Effects

  • Injection site pain: mild to moderate discomfort at the injection site.
  • Redness or swelling: localized erythema or edema.
  • Fever: transient elevation of body temperature.
  • Headache: mild to moderate headache after vaccination.
  • Fatigue: temporary feeling of tiredness.
  • Myalgia: muscle aches in the days following injection.

Serious or Rare Side Effects

  • Anaphylaxis: severe allergic reaction requiring immediate medical attention.
  • Guillain‑Barré syndrome: rare neurologic disorder reported post‑vaccination.
  • Seizures: infrequent occurrence, especially in febrile children.
  • Severe hypotension: marked drop in blood pressure after injection.
  • Extensive local reaction: large area of induration or necrosis at the site.

Precautions & Warnings

Before administering Menveo, consider the following precautions:

  • Allergy assessment: avoid in individuals with severe hypersensitivity to any vaccine component.
  • Pregnancy: use only if clearly needed; data on safety are limited.
  • Immunocompromised patients: vaccine may be less effective; assess timing relative to immunosuppressive therapy.
  • Concurrent vaccines: may be given with other vaccines at separate sites.
  • Age restriction: not approved for persons older than 55 years.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Vaccines can interact with other agents that affect immune response.

Major Interactions (Avoid)

  • Live bacterial vaccines: do not administer simultaneously; separate by at least 4 weeks.
  • Severe allergic reaction to a previous dose: contraindicates further dosing.

Moderate Interactions (Monitor Closely)

  • Immunoglobulin therapy: may reduce vaccine efficacy; avoid within 2 weeks before or after vaccination.
  • Blood products: can interfere with immune response if given close to vaccination.
  • Antipyretics: may mask fever, a common post‑vaccination sign; use as needed after monitoring.

Frequently Asked Questions

Menveo is a conjugate vaccine indicated for the prevention of invasive disease caused by Neisseria meningitidis serogroups A, C, W‑135 and Y. It is administered to individuals at risk, including adolescents, travelers to endemic areas, and people living in high‑density settings such as college dormitories.

The active ingredient consists of meningococcal polysaccharide antigens linked to the CRM197 protein carrier. This conjugation creates a T‑cell‑dependent response, prompting the immune system to produce high‑affinity antibodies that specifically target the capsular polysaccharides of serogroups A, C, W‑135 and Y, providing long‑lasting protection.

The dosing schedule for Menveo is determined by the prescribing healthcare professional based on the patient’s age, health status and vaccination history. The prescriber will decide the number of doses and the interval between them according to approved guidelines.

Safety data for Menveo in pregnancy are limited. It should only be used when clearly needed and after a risk‑benefit assessment by the healthcare provider. Breastfeeding is not a contraindication, but the prescriber should evaluate any potential risks.

To order Menveo, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, cold‑chain shipping details and import documentation.

Menveo is a quadrivalent conjugate vaccine covering serogroups A, C, W‑135 and Y, offering T‑cell‑dependent immunity and longer‑lasting protection compared with polysaccharide‑only vaccines. Its conjugate technology generally results in better immune memory and suitability for younger age groups.

Menveo must be stored at 2‑8 °C in a refrigerator. Keep the vials in the original packaging, protect them from light, and do not freeze or shake the product. Once removed from refrigeration, use within the time frame specified in the product labeling.

Menveo is given as an intramuscular injection, typically into the deltoid muscle of the upper arm. The injection is performed by a qualified healthcare professional using aseptic technique. The exact administration schedule depends on the patient’s age and prior vaccination history.

Serious risks, though rare, include anaphylaxis, severe allergic reactions, Guillain‑Barré syndrome, seizures and severe hypotension. Any signs of a severe reaction, such as difficulty breathing, swelling of the face or throat, or a rapid drop in blood pressure, require immediate medical attention.

Menveo should not be given to individuals with a known severe hypersensitivity to any component of the vaccine, including the CRM197 protein carrier. It is also not approved for use in persons older than 55 years. Contraindications and precautions should be reviewed by the prescribing clinician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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