Mephaquin Lactab (Mefloquine Hydrochloride)

Mefloquine disrupts the parasite’s heme detoxification by binding to ferriprotoporphyrin IX, preventing formation of harmless hemozoin. This leads to toxic heme buildup and parasite death. It also interferes with membrane function, further compromising the malaria parasite’s survival.

The dosage and treatment schedule for Mephaquin Lactab are determined by a qualified prescriber based on the patient’s age, weight, indication (prophylaxis or treatment), and local resistance patterns. Patients should follow the exact regimen provided by their healthcare professional.

Safety data for mefloquine in pregnancy and lactation are limited. The drug should only be used if the potential benefit outweighs the risk, and decisions must be made by a healthcare provider after evaluating the individual’s circumstances.

To place an order, submit an enquiry on the Mephaquin Lactab product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Mefloquine offers a long half‑life, allowing once‑weekly dosing for prophylaxis, which can be more convenient than daily regimens such as atovaquone‑proguanil. However, it has a higher incidence of neuropsychiatric side effects, so clinicians may choose alternatives for patients with a history of mood disorders or when rapid parasite clearance is essential.

Store Mephaquin Lactab below 25 °C in its original packaging, protected from moisture and direct sunlight. Keep the product out of reach of children and avoid exposing it to excessive heat or humidity, which could affect tablet integrity.

Mephaquin Lactab is taken orally with a full glass of water. For prophylaxis, it is usually taken once weekly with or without food, starting 1–2 weeks before exposure and continuing for 4 weeks after leaving the endemic area. For treatment, the prescriber defines the exact schedule.

The most concerning adverse events include severe neuropsychiatric reactions such as depression, anxiety, psychosis, or suicidal thoughts, as well as cardiac arrhythmias linked to QT prolongation. Prompt medical attention is required if any of these symptoms develop.

Mefloquine is contraindicated in individuals with known hypersensitivity to the drug, a history of severe psychiatric disorders, uncontrolled epilepsy, or significant cardiac disease that predisposes to arrhythmias. Pregnant or breastfeeding women should only use it when clearly indicated by a healthcare professional.