Product image of Mepivacaina B.Braun (Mepivacaine Hydrochloride) supplied by GNH India

Mepivacaina B.Braun

Active Ingredient:
Mepivacaine Hydrochloride
Origin:
EU

Mepivacaina B.Braun (Mepivacaine Hydrochloride)

Mepivacaine, the active ingredient in Mepivacaina B.Braun, is a local anesthetic presented as a solution for epidural, intra‑articular and intradermal use. It provides temporary loss of sensation for surgical, dental and diagnostic procedures in adult patients. GNH India supplies Mepivacaina B.Braun as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

B.Braun Medical, S.A.

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Indications & Clinical Uses

Mepivacaine is a local anesthetic used to block nerve conduction in various clinical settings.

  • Surgical and dental procedures: provides local anesthesia to facilitate pain‑free surgery or dental work.
  • Epidural analgesia: delivers analgesia for labor, postoperative pain, or chronic pain management.
  • Intra‑articular injection: enables joint anesthesia for arthroscopic or therapeutic procedures.
  • Intradermal infiltration: used for diagnostic skin testing or minor procedures requiring superficial anesthesia.

How It Works

  • Mepivacaine hydrochloride reversibly blocks voltage‑gated sodium channels on neuronal membranes, preventing the initiation and propagation of action potentials. By stabilizing the neuronal membrane, it inhibits nerve impulse transmission, resulting in a temporary loss of sensation in the targeted area.

Side Effects

Mepivacaina B.Braun may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Transient burning or tingling at the injection site
  • Mild hypotension
  • Nausea
  • Dizziness

Serious or Rare Side Effects

  • Cardiac arrhythmias
  • Seizures
  • Methemoglobinemia
  • Anaphylactic allergic reactions

Precautions & Warnings

Prior to administration, consider the following safety measures.

  • Allergy assessment: confirm no known hypersensitivity to amide‑type local anesthetics.
  • Cardiovascular status: avoid in patients with severe heart block or conduction disorders.
  • Neurological disorders: use cautiously in patients with epilepsy or seizure history.
  • Pregnancy and lactation: evaluate risk‑benefit, limited data are available.
  • Dosage limits: adhere to the maximum recommended dose per procedure.
  • Store at ambient temperature: keep in the original container, protect from light and moisture.

Avoid Interactions

Mepivacaina B.Braun can interact with other medications; monitor patients accordingly.

Major Interactions (Avoid)

  • Class I antiarrhythmics (e.g., quinidine, procainamide): may enhance cardiotoxicity.
  • Beta‑blockers: increase risk of bradycardia and hypotension.
  • General anesthetics (e.g., halothane): potentiate central nervous system depression.

Moderate Interactions (Monitor Closely)

  • MAO inhibitors: may increase risk of hypertension.
  • Diuretics: may alter plasma protein binding of the anesthetic.
  • Other local anesthetics: cumulative toxicity risk when used together.

Frequently Asked Questions

Mepivacaina B.Braun is used to provide local anesthesia for surgical and dental procedures, epidural analgesia during labor or postoperative pain control, intra‑articular injections for joint surgeries, and intradermal infiltration for diagnostic or minor therapeutic purposes.

Mepivacaine works by reversibly blocking voltage‑gated sodium channels on nerve membranes, which stops the initiation and propagation of electrical impulses. This interruption of nerve signaling results in a temporary loss of sensation in the area where the drug is administered.

The appropriate dose of Mepivacaina B.Braun is determined by the prescribing clinician based on the type of procedure, the site of administration, patient weight, and overall health status. No fixed regimen is provided here; the prescriber sets the exact amount.

Safety data for mepivacaine in pregnancy and lactation are limited. Use is generally reserved for situations where the benefit to the mother outweighs potential risks to the fetus or infant, and it should be administered only under careful medical supervision.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details (including cold‑chain if needed) and import documentation.

Mepivacaina B.Braun, an amide‑type anesthetic, has a slightly faster onset and longer duration than lidocaine, another common amide. It also tends to produce less vasodilation, which can reduce the need for a vasoconstrictor additive in certain procedures.

Store the product at ambient temperature, preferably below 25 °C, in its original packaging. Protect it from direct sunlight, moisture, and extreme temperature fluctuations to maintain stability and potency.

Mepivacaina B.Braun is administered by injection. It can be given epidurally, intra‑articularly, or intradermally depending on the clinical indication, using aseptic technique and appropriate needle size for the target tissue.

Serious risks include cardiac arrhythmias, seizures, methemoglobinemia, and severe allergic reactions such as anaphylaxis. These events are rare but require immediate medical attention if they occur.

Patients with known hypersensitivity to mepivacaine or other amide‑type local anesthetics, those with severe cardiac conduction disorders, and individuals with uncontrolled epilepsy should avoid using Mepivacaina B.Braun unless a specialist determines it is safe.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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