Product image of Mepivacaina Recordati (Mepivacaine Hydrochloride) supplied by GNH India

Mepivacaina Recordati

Active Ingredient:
Mepivacaine Hydrochloride
Origin:
EU

Mepivacaina Recordati (Mepivacaine Hydrochloride)

Mepivacaine, the active ingredient in Mepivacaina Recordati, is a local anesthetic presented as a sterile solution for epidural, infiltration and perineural administration. It provides reversible nerve block for surgical, dental and obstetric procedures in adult patients and is commonly employed in outpatient settings.

GNH India supplies Mepivacaina Recordati as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides full regulatory documentation to support import, distribution and clinical use across multiple regions.

Manufacturer / TM Owner

Recordati Industria Chimica E Farmaceutica S.P.A.

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Indications & Clinical Uses

  • Mepivacaine is used as a local anesthetic for regional pain control in various clinical settings.
  • Epidural analgesia: provides regional pain relief during labor, childbirth or postoperative recovery.
  • Infiltration anesthesia: produces localized numbness for minor surgical or dental procedures.
  • Peripheral nerve block: enables targeted anesthesia of specific nerve territories for orthopedic or trauma surgery.
  • Dental procedures: facilitates painless tooth extractions, restorations and periodontal surgery.
  • Surgical anesthesia: contributes to general anesthesia regimens by providing supplemental local analgesia.

How It Works

  • Mepivacaine hydrochloride reversibly blocks voltage‑gated sodium channels on neuronal membranes, inhibiting the rapid influx of sodium ions required for depolarisation. By stabilising the neuronal membrane, it prevents initiation and propagation of nerve impulses, resulting in a temporary loss of sensation in the administered area.

Side Effects

Adverse reactions to mepivacaine are generally related to its local anaesthetic properties or systemic absorption.

Common Side Effects

  • Transient numbness at injection site
  • Mild tingling or paresthesia
  • Local swelling or erythema

Serious or Rare Side Effects

  • Cardiac arrhythmias, including ventricular tachycardia
  • Seizures due to central nervous system toxicity
  • Severe allergic reactions (anaphylaxis)

Precautions & Warnings

  • When using mepivacaine, clinicians should observe several precautionary measures to minimise risk.
  • Allergy assessment: verify no hypersensitivity to amide‑type local anesthetics
  • Cardiovascular monitoring: observe for arrhythmias in patients with cardiac disease
  • Dose adjustment: consider reduced dose in elderly or patients with hepatic impairment
  • Concurrent CNS depressants: use caution when combined with other central nervous system depressants
  • Store at ambient temperature: keep in original container, protect from light and moisture

Avoid Interactions

Mepivacaine may interact with other medicines, altering its toxicity or efficacy.

Major Interactions (Avoid)

  • Class I antiarrhythmic agents (e.g., quinidine, procainamide): increase risk of systemic toxicity
  • Beta‑blockers: may potentiate bradycardia and hypotension

Moderate Interactions (Monitor Closely)

  • Monoamine oxidase inhibitors: can enhance central nervous system effects
  • Tricyclic antidepressants: may increase risk of seizures
  • Other local anesthetics: additive toxicity when used concurrently
  • CNS depressants (e.g., opioids, benzodiazepines): may deepen sedation

Frequently Asked Questions

Mepivacaina Recordati contains mepivacaine hydrochloride, a local anesthetic employed to provide regional pain control. It is indicated for epidural analgesia during labor or surgery, infiltration anesthesia for minor procedures, peripheral nerve blocks for orthopedic interventions, dental surgeries, and as an adjunct in general surgical anesthesia.

Mepivacaine works by reversibly blocking voltage‑gated sodium channels on neuronal membranes. This inhibition prevents the rapid influx of sodium ions needed for depolarisation, thereby stopping the initiation and propagation of nerve impulses and producing a temporary loss of sensation in the targeted area.

The appropriate dose of Mepivacaina Recordati is determined by the prescribing clinician based on the specific procedure, patient characteristics, and route of administration. Dosage must be individualized and follows local regulatory and clinical guidelines.

Safety data for mepivacaine during pregnancy and lactation are limited. The drug should only be used if the potential benefit justifies any possible risk to the fetus or infant, and the decision should be made by the treating physician in consultation with the patient.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if required) and necessary import documentation.

Mepivacaine is an amide‑type local anesthetic with a rapid onset and intermediate duration, similar to lidocaine but with slightly longer analgesic effect and less vasodilatory activity. This can reduce the need for vasoconstrictors in certain procedures, making it a useful alternative when a longer block is desired.

Store the product at ambient temperature, preferably below 25 °C, in its original packaging. Protect it from direct light, moisture and extreme temperature fluctuations. Ensure the container is sealed when not in use and keep it out of reach of children.

Mepivacaina Recordati is supplied as a sterile solution for injection. It is administered by a qualified healthcare professional via epidural, infiltration or perineural routes, depending on the clinical indication. Proper aseptic technique and dosage calculation are essential for safe use.

Serious risks include cardiovascular toxicity such as arrhythmias, central nervous system toxicity leading to seizures, and severe allergic reactions including anaphylaxis. Prompt recognition and management of these events are critical, and patients should be monitored closely during and after administration.

Patients with known hypersensitivity to mepivacaine, other amide‑type local anesthetics, or any component of the formulation should avoid its use. Caution is also advised for individuals with significant cardiac conduction disorders, severe hepatic impairment, or those taking interacting medications as listed in the interaction section.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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