Product image of Mercalm (Dimenhydrinate, Caffeine) supplied by GNH India

Mercalm

Active Ingredient:
Dimenhydrinate, Caffeine
Origin:
EU

Mercalm (Dimenhydrinate, Caffeine)

Dimenhydrinate, the active ingredient in Mercalm, is an antihistamine presented as a tablet for oral use. It treats motion‑induced nausea, vomiting and vertigo in adults and children.
GNH India supplies Mercalm as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Melisana Pharma

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Dimenhydrinate, combined with caffeine, acts on the vestibular system and histamine pathways to control nausea and related symptoms.

  • Motion Sickness: reduces vertigo, nausea and vomiting associated with travel.
  • Post‑operative Nausea: helps control nausea and vomiting after surgical procedures.
  • Vertigo: alleviates dizziness caused by vestibular disturbances.

How It Works

  • Dimenhydrinate blocks H1 histamine receptors and exerts anticholinergic effects, diminishing vestibular stimulation that triggers nausea. Caffeine acts as a central nervous system stimulant by antagonising adenosine receptors, which can counteract drowsiness and enhance alertness, supporting the anti‑emetic action of dimenhydrinate.

Side Effects

Common Side Effects

  • Drowsiness: mild sedation or fatigue.
  • Dry Mouth: reduced salivation leading to throat discomfort.
  • Blurred Vision: temporary visual disturbances.
  • Constipation: slowed gastrointestinal motility.
  • Headache: mild to moderate head pain.
  • Increased Heart Rate: mild tachycardia.

Serious or Rare Side Effects

  • Allergic Reactions: rash, swelling, or urticaria.
  • Cardiac Arrhythmia: irregular heart rhythms.
  • Seizures: rare convulsive episodes.
  • Severe Hypotension: marked drop in blood pressure.
  • Confusion or Hallucinations: altered mental status.
  • Respiratory Depression: difficulty breathing in severe cases.

Precautions & Warnings

Before using Mercalm, consider the following precautions:

  • Glaucoma: avoid if you have narrow‑angle glaucoma.
  • Urinary Retention: use cautiously in patients with prostate enlargement.
  • Asthma: monitor for bronchospasm.
  • Pregnancy: consult a healthcare professional before use.
  • Elderly: start with the lowest effective dose.
  • Drug Interactions: review concomitant medications.
  • Store below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Dimenhydrinate may interact with several drug classes.

Major Interactions (Avoid)

  • MAO Inhibitors: risk of hypertensive crisis.
  • CNS Depressants: additive sedation.
  • Anticholinergic Drugs: excessive anticholinergic load.
  • Alcohol: enhanced drowsiness.
  • Certain Antidepressants: increased anticholinergic effects.

Moderate Interactions (Monitor Closely)

  • Antihypertensives: possible additive blood pressure lowering.
  • Diuretics: may enhance dehydration.
  • Other Antihistamines: increased sedation.
  • CYP1A2 Inhibitors (e.g., ciprofloxacin): elevated caffeine levels.
  • Antacids: may affect absorption.

Frequently Asked Questions

Mercalm is an oral anti‑emetic medication that combines dimenhydrinate and caffeine to treat motion‑induced nausea, vomiting, postoperative nausea, and vertigo. It is commonly prescribed for travelers, surgical patients, and individuals experiencing vestibular disturbances.

Dimenhydrinate works by blocking H1 histamine receptors and exerting anticholinergic activity, which reduces stimulation of the vestibular system that triggers nausea. This dual action helps control vomiting and dizziness associated with motion or vestibular disorders.

The dosage of Mercalm is determined by the prescribing healthcare professional based on the patient’s age, weight, condition severity, and response to therapy. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Pregnancy and breastfeeding safety should be evaluated by a qualified healthcare provider. Dimenhydrinate is classified as Category B in many regions, indicating no proven risk in animal studies, but human data are limited. Caffeine exposure should also be considered.

To order Mercalm, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and import documentation.

Compared with other antihistamine anti‑emetics such as meclizine, Mercalm adds caffeine, which can reduce drowsiness and improve alertness. It offers a broader symptom control for motion sickness but may have a higher incidence of stimulant‑related side effects.

Mercalm should be stored at temperatures below 25 °C, in its original packaging, protected from moisture and direct sunlight. Keep the product out of reach of children and do not use if the packaging is damaged.

Mercalm is taken orally, usually with a glass of water. The tablet should be swallowed whole and not chewed or crushed unless directed by a healthcare professional. It can be taken with or without food, depending on tolerability.

Serious risks include severe allergic reactions (rash, swelling, difficulty breathing), cardiac arrhythmias, seizures, and marked hypotension. Patients should seek immediate medical attention if they experience any of these symptoms.

Mercalm should be avoided in individuals with known hypersensitivity to dimenhydrinate, caffeine, or any excipients, as well as patients with narrow‑angle glaucoma, severe urinary retention, uncontrolled asthma, or those taking MAO inhibitors.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Dimenhydrinate, Caffeine

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT