Product image of Mercilon (Desogestrel, Ethinylestradiol) supplied by GNH India

Mercilon

Active Ingredient:
Desogestrel, Ethinylestradiol
Origin:
EU

Mercilon (Desogestrel, Ethinylestradiol)

Desogestrel and Ethinylestradiol, the active ingredients in Mercilon, are a combined oral contraceptive presented as a 0.15 mg/0.02 mg tablet for oral use. It is prescribed to prevent pregnancy and to help regulate the menstrual cycle in women of reproductive age.

GNH India supplies Mercilon as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

N.V. Organon

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Indications & Clinical Uses

  • Mercilon, a combined oral contraceptive, is indicated for hormonal regulation of the reproductive system.
  • Prevention of pregnancy: provides reliable contraceptive protection for women of reproductive age.
  • Menstrual cycle regulation: helps achieve more predictable bleeding patterns.
  • Treatment of moderate acne: improves skin lesions associated with hormonal fluctuations.

How It Works

  • Desogestrel and ethinylestradiol act together to suppress the hypothalamic‑pituitary‑ovarian axis, reducing the secretion of luteinizing hormone and follicle‑stimulating hormone, which prevents ovulation. The estrogen component stabilises the endometrial lining, while the progestogen thickens cervical mucus and induces endometrial changes that together impede fertilisation and implantation.

Side Effects

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Headache: tension‑type or migraine‑like pain.
  • Breast tenderness: temporary swelling or soreness.
  • Spotting between periods: irregular light bleeding.
  • Mood changes: irritability or emotional fluctuations.
  • Weight gain: modest increase in body weight.

Serious or Rare Side Effects

  • Venous thromboembolism: blood clots in deep veins.
  • Pulmonary embolism: clot migration to lungs.
  • Stroke: cerebrovascular accident, especially in high‑risk women.
  • Myocardial infarction: heart attack in susceptible individuals.
  • Severe hypertension: sudden rise in blood pressure.
  • Liver tumor: rare hepatic adenoma development.

Precautions & Warnings

  • Before prescribing Mercilon, clinicians should assess individual risk factors and contraindications.
  • Pregnancy contraindication: must not be used during pregnancy.
  • Smoking in women >35 years: avoid due to increased cardiovascular risk.
  • History of thromboembolism: contraindicated because of clot risk.
  • Uncontrolled hypertension: may exacerbate blood pressure.
  • Severe liver disease: impaired metabolism can increase drug levels.
  • Store at ambient temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Mercilon may interact with several medicines that alter its effectiveness or safety.

Major Interactions (Avoid)

  • Rifampin, phenytoin, carbamazepine: enzyme inducers that reduce contraceptive efficacy.
  • Ritonavir, other protease inhibitors: may increase hormone levels, raising clot risk.
  • St. John's wort: herbal inducer that lowers plasma concentrations.
  • Certain antifungals (ketoconazole): can increase hormone levels, heightening side‑effect risk.

Moderate Interactions (Monitor Closely)

  • SSRIs (e.g., fluoxetine): may modestly affect hormone metabolism.
  • Antihypertensives: oral contraceptives can reduce blood‑pressure control.
  • Diuretics: may increase risk of electrolyte imbalance.
  • Anticonvulsants (e.g., valproate): may require dosage adjustment.
  • Ginseng: possible mild reduction in contraceptive effect.

Frequently Asked Questions

Mercilon is a combined oral contraceptive containing desogestrel and ethinylestradiol. It is prescribed to prevent pregnancy and to help regulate menstrual cycles in women of reproductive age.

The two hormones suppress the hypothalamic‑pituitary‑ovarian axis, lowering luteinising hormone and follicle‑stimulating hormone release, which stops ovulation. Desogestrel also thickens cervical mucus, while ethinylestradiol stabilises the endometrium, together preventing fertilisation and implantation.

The dosing regimen for Mercilon is determined by the prescribing clinician. Typically, it is taken as one tablet daily at the same time each day, but the exact schedule should follow the healthcare provider’s instructions.

Mercilon is classified as pregnancy category X, meaning it must not be used during pregnancy. It is also not recommended while breastfeeding because hormones can pass into breast milk and may affect the infant.

To order Mercilon, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Mercilon contains a low‑dose estrogen (0.02 mg ethinylestradiol) combined with desogestrel, which may offer a more favourable bleeding profile and lower risk of estrogen‑related side effects compared with higher‑dose formulations. Clinical choice depends on individual risk factors and patient preference.

Mercilon tablets should be stored at ambient temperature, below 25 °C, in the original packaging to protect them from moisture and light. Keep the container tightly closed and out of reach of children.

Mercilon is taken orally as a tablet. The usual practice is to swallow one tablet each day, preferably at the same time each day, with or without food, following the prescriber’s schedule.

The most serious risks include venous thromboembolism, pulmonary embolism, stroke, myocardial infarction, severe hypertension, and rare liver tumors. Women with a history of clotting disorders, smoking, or certain cardiovascular conditions should be evaluated carefully before use.

Mercilon should not be used by women who are pregnant, have known or suspected breast cancer, have a history of thromboembolic disease, uncontrolled hypertension, severe liver disease, or who smoke cigarettes and are over 35 years of age.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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