Product image of Mercilon (Desogestrel, Ethinylestradiol) supplied by GNH India

Mercilon

Active Ingredient:
Desogestrel, Ethinylestradiol
Origin:
EU

Mercilon (Desogestrel, Ethinylestradiol)

Desogestrel/Ethinylestradiol, the active ingredient in Mercilon, is a combined oral contraceptive presented as a tablet for oral use. It prevents pregnancy in women of reproductive age.

GNH India supplies Mercilon as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Organon Hungary Kft.

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Indications & Clinical Uses

  • Mercilon, a combined oral contraceptive, is indicated for hormonal regulation to prevent pregnancy and manage menstrual‑related conditions.
  • Contraception: prevents unintended pregnancy in women of childbearing potential.
  • Menstrual cycle regulation: provides predictable monthly bleeding and reduces cycle irregularities.
  • Moderate acne treatment: improves skin lesions associated with hormonal acne in women.

How It Works

  • Desogestrel/Ethinylestradiol works by suppressing the mid‑cycle surge of luteinising hormone (LH) and follicle‑stimulating hormone (FSH), thereby inhibiting ovulation. The estrogen component stabilises the endometrial lining, while the progestin thickens cervical mucus, creating a hostile environment for sperm and reducing the likelihood of implantation.

Side Effects

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Headache: tension‑type or migraine‑like pain.
  • Breast tenderness: swelling or discomfort.
  • Spotting or breakthrough bleeding: irregular light bleeding.
  • Mood changes: irritability or mild depression.
  • Weight fluctuation: slight increase or fluid retention.

Serious or Rare Side Effects

  • Deep vein thrombosis: blood clot formation in legs.
  • Pulmonary embolism: clot traveling to lungs.
  • Stroke or transient ischemic attack: neurological events.
  • Myocardial infarction: heart attack risk.
  • Severe allergic reaction: rash, swelling, anaphylaxis.
  • Liver dysfunction: jaundice or abnormal liver enzymes.

Precautions & Warnings

Before initiating Mercilon, consider the following safety measures.

  • Cardiovascular risk assessment: evaluate history of thrombosis, smoking, hypertension.
  • Pregnancy status: discontinue if pregnancy is confirmed.
  • Age and smoking: avoid use in women over 35 who smoke.
  • Hepatic function: use with caution in liver disease.
  • Drug interaction review: assess concomitant medications that affect estrogen metabolism.
  • Store at ambient temperature: keep below 25°C, protect from moisture and light.

Avoid Interactions

Mercilon may interact with several medicines; monitoring is essential.

Major Interactions (Avoid)

  • Strong CYP3A4 inducers (e.g., rifampicin, phenytoin): may markedly reduce contraceptive efficacy.
  • Protease inhibitors (e.g., ritonavir): can increase estrogen exposure and risk of side effects.

Moderate Interactions (Monitor Closely)

  • Antifungal azoles (e.g., ketoconazole): may raise plasma hormone levels.
  • Selective serotonin reuptake inhibitors (e.g., fluoxetine): can increase bleeding tendency.
  • Anticoagulants (e.g., warfarin): may enhance anticoagulant effect and raise INR.

Frequently Asked Questions

Mercilon is a combined oral contraceptive containing desogestrel and ethinylestradiol. It is prescribed to prevent unintended pregnancy and can also help regulate menstrual cycles and improve hormonal acne in women of reproductive age.

The combination suppresses the mid‑cycle surge of luteinising hormone and follicle‑stimulating hormone, preventing ovulation. Desogestrel thickens cervical mucus, while ethinylestradiol stabilises the endometrial lining, together creating conditions that inhibit fertilisation and implantation.

The dosing regimen for Mercilon is determined by the prescribing healthcare professional. Typically, it is taken as one tablet daily at the same time each day, but the exact schedule and duration should follow the prescriber’s instructions.

Mercilon is contraindicated during pregnancy; it should be stopped if pregnancy is confirmed. Limited data exist for use while breastfeeding, and the decision should be made by a healthcare provider weighing potential risks and benefits.

To place an order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Mercilon contains desogestrel, a third‑generation progestin, which is associated with a lower incidence of androgenic side effects compared with older progestins. Its efficacy in preventing pregnancy is comparable to other combined oral contraceptives, while the side‑effect profile may differ slightly based on the specific progestin used.

Mercilon tablets should be stored at ambient temperature, preferably below 25 °C, in their original packaging to protect from moisture and light. Keep the container tightly closed and out of reach of children.

Mercilon is taken orally as a tablet. The usual practice is to swallow one tablet each day, preferably at the same time each day, with or without food, following the prescriber’s schedule.

Serious risks include venous thromboembolism (deep‑vein thrombosis, pulmonary embolism), arterial events such as stroke or myocardial infarction, severe allergic reactions, and liver dysfunction. Women with a history of clotting disorders, smoking, or certain cardiovascular conditions should discuss these risks with their clinician.

Mercilon is contraindicated in women who are pregnant, have a known or suspected breast cancer, have a history of thromboembolic disorders, uncontrolled hypertension, severe liver disease, or are smokers aged 35 years or older. A thorough medical evaluation is required before initiating therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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