Product image of Mercilon (Desogestrel, Ethinylestradiol) supplied by GNH India

Mercilon

Active Ingredient:
Desogestrel, Ethinylestradiol
Origin:
EU

Mercilon (Desogestrel, Ethinylestradiol)

Desogestrel/Ethinylestradiol, the active ingredients in Mercilon, are a combined oral contraceptive presented as an oral tablet for oral use. It is indicated for prevention of pregnancy and may be used to regulate menstrual cycles in women of reproductive age.

GNH India supplies Mercilon as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

N.V. Organon

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Indications & Clinical Uses

Mercilon is a combined hormonal contraceptive that acts on the hypothalamic‑pituitary‑ovarian axis to prevent pregnancy and manage menstrual disorders.

  • Contraception: prevents pregnancy by suppressing ovulation and altering cervical mucus.
  • Menstrual cycle regulation: provides more predictable bleeding patterns and reduces dysmenorrhea.
  • Acne improvement (off‑label): may lessen androgen‑related acne in some women.

How It Works

  • Desogestrel is a progestogen that inhibits the mid‑cycle surge of luteinizing hormone, thereby preventing ovulation, while ethinylestradiol provides estrogenic feedback that stabilises the endometrium and modifies cervical mucus. Together they create an environment unsuitable for fertilisation and implantation.

Side Effects

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Breast tenderness: temporary swelling or discomfort.
  • Headache: occasional tension‑type headache.
  • Breakthrough bleeding: spotting between periods.
  • Mood changes: mild emotional fluctuations.
  • Weight gain: slight increase in body weight.

Serious or Rare Side Effects

  • Venous thromboembolism: blood clots in deep veins or lungs.
  • Arterial thrombosis: clot formation in arteries, leading to stroke or heart attack.
  • Hypertension: significant rise in blood pressure.
  • Liver tumor: benign hepatic adenoma.
  • Gallbladder disease: formation of gallstones.
  • Severe allergic reaction: anaphylaxis or angioedema.

Precautions & Warnings

Before starting Mercilon, consider the following precautions.

  • Contraindicated in women with a history of thromboembolic disorders: avoid use.
  • Do not use if pregnant: discontinue immediately.
  • Smoking over 15 cigarettes per day: increased cardiovascular risk.
  • Monitor blood pressure regularly: risk of hypertension.
  • Review concurrent medications: see interaction section.
  • Store at ambient temperature: keep in the original pack, protect from moisture and light.

Avoid Interactions

Mercilon may interact with several medicines, affecting its efficacy or safety.

Major Interactions (Avoid)

  • Enzyme‑inducing antiepileptics (e.g., carbamazepine, phenytoin): markedly reduce hormonal levels.
  • Rifampin: decreases contraceptive effectiveness.

Moderate Interactions (Monitor Closely)

  • Broad‑spectrum antibiotics (e.g., ampicillin): may slightly lower efficacy.
  • Azole antifungals (e.g., fluconazole): can increase hormone concentrations.
  • Selective serotonin reuptake inhibitors (e.g., fluoxetine): may raise bleeding risk.

Frequently Asked Questions

Mercilon is a combined oral contraceptive indicated primarily for the prevention of pregnancy. It is also prescribed to help regulate menstrual cycles and may be used off‑label to improve mild acne in women of reproductive age.

Desogestrel suppresses the mid‑cycle luteinizing hormone surge, preventing ovulation, while ethinylestradiol provides estrogenic feedback that stabilises the endometrium and thickens cervical mucus. Together they create conditions that inhibit fertilisation and implantation.

The dosing regimen for Mercilon is determined by the prescribing healthcare professional. Typically, it is taken as one tablet daily at the same time each day, but the exact schedule and duration should follow the prescriber's instructions.

Mercilon is contraindicated during pregnancy and should be stopped if pregnancy occurs. Limited data exist for breastfeeding; however, most guidelines advise caution and suggest discussing alternatives with a healthcare provider.

To order Mercilon, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Mercilon contains desogestrel, a third‑generation progestogen, which is associated with a lower incidence of androgenic side effects compared with older progestins. Its efficacy in preventing pregnancy is comparable to other combined pills, while the side‑effect profile may differ slightly in terms of weight change and mood effects.

Mercilon tablets should be stored at ambient temperature, below 25 °C, in the original blister pack to protect them from moisture and light. Keep out of reach of children and do not use after the expiry date printed on the packaging.

Mercilon is taken orally, usually as a single tablet each day, preferably at the same time each day. It should be swallowed with water and can be taken with or without food, unless otherwise directed by a healthcare professional.

The most serious risks include venous thromboembolism, arterial thrombosis (such as stroke or myocardial infarction), severe hypertension, and rare liver tumours. Women should seek immediate medical attention if they experience unexplained leg pain, chest pain, severe headache, or visual disturbances.

Mercilon should not be used by women with a history of thromboembolic disease, uncontrolled hypertension, known or suspected breast cancer, active liver disease, or those who are pregnant. Smoking more than 15 cigarettes per day and women over 35 years of age are also advised against its use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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