Product image of Mercilon (Desogestrel, Ethinylestradiol) supplied by GNH India

Mercilon

Active Ingredient:
Desogestrel, Ethinylestradiol
Origin:
EU

Mercilon (Desogestrel, Ethinylestradiol)

Desogestrel/Ethinylestradiol, the active ingredient in Mercilon, is a combined oral contraceptive presented as a tablet for oral use. It works by preventing ovulation and creating conditions in the uterus and cervical mucus that reduce the likelihood of pregnancy in women of reproductive age.

GNH India supplies Mercilon as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring consistent quality and regulatory compliance for global distribution. Our supply chain adheres to EU standards and includes temperature‑controlled logistics where required.

Manufacturer / TM Owner

N.V. Organon

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Indications & Clinical Uses

Mercilon, a combined oral contraceptive, is indicated for hormonal contraception and related menstrual management.

  • Prevention of pregnancy: Provides reliable contraception for women of reproductive age.
  • Cycle regulation: Helps establish regular menstrual bleeding patterns.
  • Reduction of menstrual flow: Decreases the amount and duration of menstrual bleeding.

How It Works

  • Desogestrel/Ethinylestradiol combines a synthetic progestogen (desogestrel) with an estrogen (ethinylestradiol). The estrogen stabilizes the endometrial lining while the progestogen suppresses the mid‑cycle luteinizing hormone surge, thereby inhibiting ovulation. Both hormones also thicken cervical mucus and alter endometrial receptivity, creating multiple barriers to fertilisation and implantation.

Side Effects

Common Side Effects

  • Nausea: Mild to moderate stomach upset, often transient.
  • Breast tenderness: Sensitivity or swelling of breast tissue.
  • Headache: Tension‑type or migraine‑like pain.
  • Spotting: Light bleeding between periods.
  • Weight gain: Slight increase in body weight, usually fluid‑related.
  • Mood changes: Irritability or mild mood swings.

Serious or Rare Side Effects

  • Thromboembolic events: Deep vein thrombosis or pulmonary embolism.
  • Hypertension: Significant increase in blood pressure.
  • Liver dysfunction: Jaundice or abnormal liver enzymes.
  • Severe allergic reaction: Rash, swelling, or anaphylaxis.
  • Visual disturbances: Sudden loss of vision or eye pain.
  • Stroke: Neurological deficits due to cerebrovascular accident.

Precautions & Warnings

Before prescribing Mercilon, clinicians should evaluate individual risk factors and counsel patients on safe use.

  • Assess thrombotic risk: Review personal and family history of clotting disorders.
  • Screen for hypertension: Measure blood pressure prior to initiation.
  • Avoid smoking in women >35 years: Smoking markedly increases cardiovascular risk.
  • Monitor liver function: Use cautiously in patients with hepatic impairment.
  • Counsel on missed pills: Provide clear instructions for managing skipped doses.
  • Store at room temperature: Keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Mercilon may interact with several medications that affect hormone metabolism or efficacy.

Major Interactions (Avoid)

  • Strong CYP3A4 inducers (e.g., rifampin, carbamazepine): May markedly reduce contraceptive effectiveness.
  • Certain antifungal agents (e.g., ketoconazole): Can increase estrogen levels and raise the risk of side effects.

Moderate Interactions (Monitor Closely)

  • Some antibiotics (e.g., tetracycline): May slightly diminish contraceptive reliability.
  • St. John’s Wort: Herbal supplement that can lower hormone concentrations.
  • Diuretics: May exacerbate blood pressure changes associated with estrogen.

Frequently Asked Questions

Mercilon is a combined oral contraceptive that contains desogestrel and ethinylestradiol. It is prescribed to prevent pregnancy in women of reproductive age by inhibiting ovulation and creating conditions that reduce the chance of fertilisation and implantation.

The ethinylestradiol component stabilises the uterine lining, while desogestrel suppresses the mid‑cycle surge of luteinising hormone, preventing ovulation. Together they also thicken cervical mucus and alter the endometrium, providing multiple mechanisms that block conception.

The dosing regimen for Mercilon is determined by the prescribing clinician. Typically, it is taken as a daily oral tablet following the specific schedule indicated on the product label, but the exact regimen should be confirmed with a qualified healthcare professional.

Mercilon is intended for use only when pregnancy is not desired. It should not be started during an existing pregnancy, and women who become pregnant while taking it should discontinue use. Breastfeeding mothers should consult their physician, as hormonal contraceptives may affect milk production and infant exposure.

To place an order, submit an enquiry on the Mercilon product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Mercilon contains desogestrel, a third‑generation progestogen, combined with ethinylestradiol. Compared with older formulations that use levonorgestrel, desogestrel may offer a lower risk of androgenic side effects such as acne, while providing similar contraceptive efficacy. Choice of product should be guided by individual risk factors and physician recommendation.

Mercilon tablets should be stored at room temperature, below 25 °C. Keep them in the original packaging, protect from moisture and direct sunlight, and ensure the container is tightly closed to maintain product stability throughout its shelf life.

Mercilon is taken orally as a tablet, usually once daily at the same time each day. The standard regimen involves a 21‑day active tablet sequence followed by a 7‑day hormone‑free interval, during which withdrawal bleeding typically occurs.

Serious risks include thromboembolic events such as deep‑vein thrombosis or pulmonary embolism, especially in women with pre‑existing clotting disorders, smokers over 35, or those with uncontrolled hypertension. Rare but severe complications can also involve liver dysfunction, stroke, or severe allergic reactions.

Mercilon is contraindicated in women with a history of thromboembolic disease, known or suspected breast cancer, uncontrolled hypertension, severe liver disease, or those who are pregnant. It should also be avoided by smokers over the age of 35 and individuals with known hypersensitivity to any component of the tablet.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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