Product image of Mercilon (Desogestrel, Ethinylestradiol) supplied by GNH India

Mercilon

Active Ingredient:
Desogestrel, Ethinylestradiol
Origin:
EU

Mercilon (Desogestrel, Ethinylestradiol)

Desogestrel, the active ingredient in Mercilon, is a combined oral contraceptive presented as an oral tablet for oral use. It is used to prevent pregnancy in women of reproductive age by providing hormonal regulation that suppresses ovulation.

GNH India supplies Mercilon as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Organon Biosciences S.R.L.

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Indications & Clinical Uses

Mercilon is a combined hormonal contraceptive indicated for use in the prevention of pregnancy and related menstrual regulation.

  • Prevention of pregnancy: provides reliable contraception by inhibiting ovulation.
  • Oral contraceptive use: offers a daily hormonal regimen for birth control.
  • Cycle regulation: helps achieve more predictable menstrual bleeding patterns.

How It Works

  • Desogestrel/Ethinylestradiol combines a progestin with an estrogen to suppress the hypothalamic‑pituitary‑gonadal axis, inhibiting gonadotropin release and preventing follicular development. The estrogen component stabilises the endometrial lining, while the progestin induces cervical mucus changes that impede sperm penetration, together preventing implantation.

Side Effects

Mercilon may cause a range of adverse reactions.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Breast tenderness: discomfort or swelling of the breasts.
  • Headache: occasional throbbing or tension‑type pain.
  • Weight change: slight increase or decrease in body weight.
  • Mood changes: irritability or mild depressive symptoms.
  • Breakthrough bleeding: spotting between periods.

Serious or Rare Side Effects

  • Deep vein thrombosis: blood clot formation in deep veins.
  • Pulmonary embolism: clot migration to lung vessels.
  • Stroke: cerebrovascular accident due to clot or hemorrhage.
  • Myocardial infarction: heart attack risk, especially in high‑risk groups.
  • Severe allergic reaction: rash, swelling, or anaphylaxis.
  • Liver dysfunction: jaundice or abnormal liver enzyme levels.

Precautions & Warnings

Before prescribing Mercilon, clinicians should evaluate individual risk factors and contraindications.

  • Contraindication in pregnancy: drug is contraindicated for pregnant women.
  • Cardiovascular risk assessment: avoid in smokers over 35 years or those with thromboembolic history.
  • Liver disease caution: use with care in patients with hepatic impairment.
  • Blood pressure monitoring: may cause slight elevation; monitor regularly.
  • Drug interaction review: assess concomitant medications for potential efficacy reduction.
  • Store at ambient temperature: keep in original packaging, protect from moisture and heat.

Avoid Interactions

Mercilon can interact with several medicines, altering its effectiveness or safety profile.

Major Interactions (Avoid)

  • Enzyme‑inducing anticonvulsants (e.g., carbamazepine, phenytoin): may reduce contraceptive efficacy.
  • Rifampicin and other strong CYP3A4 inducers: can markedly lower hormone levels.
  • St. John's wort: herbal inducer that may compromise birth control.

Moderate Interactions (Monitor Closely)

  • Antifungal agents (e.g., ketoconazole): may increase plasma hormone concentrations.
  • Certain antiretrovirals (e.g., protease inhibitors): may elevate risk of thrombotic events.

Frequently Asked Questions

Mercilon is prescribed as a combined oral contraceptive to prevent pregnancy. It delivers a fixed dose of desogestrel and ethinylestradiol daily, providing reliable hormonal birth control for women of reproductive age.

The combination suppresses the release of gonadotropins from the pituitary, preventing ovulation. Desogestrel, a progestin, thickens cervical mucus and alters the endometrium, while ethinylestradiol stabilises the uterine lining, together blocking fertilisation and implantation.

The dosing regimen for Mercilon is determined by the prescribing clinician. Typically, it is taken as one tablet daily at the same time each day, but the exact schedule and duration are set according to individual medical assessment.

Mercilon is contraindicated during pregnancy and should not be started in pregnant women. While limited data exist for breastfeeding, most guidelines advise caution and recommend discussing alternatives with a healthcare professional.

To order Mercilon, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Mercilon contains desogestrel, a third‑generation progestin, which is associated with a lower incidence of androgenic side effects compared with some older progestins. Its efficacy in preventing pregnancy is comparable to other combined pills, while the side‑effect profile may differ slightly based on the progestin component.

Mercilon tablets should be stored at ambient temperature, below 25 °C, in the original blister pack to protect from moisture and light. Keep the medication out of reach of children and do not use after the expiry date.

Mercilon is taken orally as a single tablet each day, preferably at the same time each day. It is usually started on the first day of the menstrual cycle or after a 7‑day placebo interval, following the prescribing clinician’s instructions.

Serious risks include venous thromboembolism, pulmonary embolism, stroke, myocardial infarction, severe allergic reactions, and liver dysfunction. These events are more likely in women with pre‑existing cardiovascular risk factors, smoking history, or certain genetic predispositions.

Mercilon should not be used by women who are pregnant, have a history of thromboembolic disorders, uncontrolled hypertension, active liver disease, known or suspected breast cancer, or who smoke cigarettes and are over 35 years of age.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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