Product image of Meriofert (Luteinising Hormone (Human), Follicle-Stimulating Hormone) supplied by GNH India

Meriofert

Active Ingredient:
Luteinising Hormone (Human), Follicle-Stimulating Hormone
Origin:
EU

Meriofert (Luteinising Hormone (Human), Follicle-Stimulating Hormone)

Luteinising hormone (human), Follicle‑stimulating hormone, the active ingredient in Meriofert, is a gonadotropin presented as an injectable solution for intramuscular and subcutaneous use. It is indicated for infertility caused by hypogonadotropic hypogonadism and for stimulating follicular development in assisted reproductive technology such as IVF.

GNH India supplies Meriofert as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with the product sourced from the European Union market and adheres to stringent quality standards.

Manufacturer / TM Owner

Ibsa Farmaceutici Italia

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Indications & Clinical Uses

  • Meriofert, a gonadotropin used in reproductive endocrinology, is employed to address specific infertility conditions.
  • Infertility due to hypogonadotropic hypogonadism: restores endogenous gonadal hormone production to enable ovulation or spermatogenesis.
  • Assisted reproductive technology (IVF): stimulates follicular development to obtain multiple oocytes for retrieval.
  • Ovulation induction in anovulatory women: promotes follicular growth leading to ovulation.

How It Works

  • Meriofert contains human luteinising hormone and follicle‑stimulating hormone which bind to LH and FSH receptors on ovarian or testicular cells. Receptor activation triggers intracellular signaling that enhances steroid hormone synthesis and gametogenesis, supporting follicular maturation, ovulation, and spermatogenesis as required for fertility treatment.

Side Effects

Common Side Effects

  • Injection site pain or erythema.
  • Mild abdominal discomfort or bloating.
  • Nausea or headache.
  • Transient fluid retention.

Serious or Rare Side Effects

  • Ovarian hyperstimulation syndrome, potentially severe.
  • Multiple pregnancy.
  • Allergic reactions including anaphylaxis.
  • Severe abdominal pain indicating possible ovarian torsion.
  • Thromboembolic events.

Precautions & Warnings

Precautions for Meriofert include careful patient monitoring and adherence to handling guidelines.

  • Monitor ovarian response: perform serial ultrasound and estradiol assessments.
  • Avoid use in uncontrolled thyroid disease: assess thyroid function before initiation.
  • Assess for pituitary adenomas: evaluate pituitary status when indicated.
  • Use caution in patients with thromboembolic risk: consider prophylactic measures.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Meriofert may interact with other medications affecting reproductive hormone pathways.

Major Interactions (Avoid)

  • GnRH antagonists: may blunt the therapeutic response.
  • High‑dose estrogen therapy: can interfere with gonadotropin efficacy.

Moderate Interactions (Monitor Closely)

  • Oral contraceptives: may alter baseline hormone levels; discontinue before treatment.
  • Thyroid hormone replacement: monitor thyroid status during therapy.
  • Diuretics: may affect fluid balance; observe for signs of dehydration.

Frequently Asked Questions

Meriofert is an injectable gonadotropin containing human luteinising hormone and follicle‑stimulating hormone. It is used to treat infertility caused by hypogonadotropic hypogonadism and to stimulate follicular development in assisted reproductive technologies such as in‑vitro fertilisation.

The hormones in Meriofert bind to LH and FSH receptors on ovarian or testicular cells. This activates intracellular pathways that increase steroid hormone production and promote gamete development, leading to follicle growth, ovulation, or spermatogenesis required for fertility.

The dose of Meriofert is individualized. The prescribing clinician determines the amount, frequency, and duration based on the patient’s specific condition, response to therapy, and treatment protocol.

Meriofert is intended for use in patients seeking to achieve pregnancy and is not administered during an established pregnancy. Safety during breastfeeding has not been established, and the medication should only be used under medical supervision.

To order Meriofert, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain handling if needed) and any required import documentation.

Meriofert provides both LH and FSH activity in a single preparation, whereas some alternatives contain only one hormone and require separate administration. This combined approach can simplify dosing schedules and may improve follicular response in certain protocols, but the choice depends on the clinician’s assessment of the patient’s needs.

Meriofert must be stored refrigerated at 2‑8 °C. Keep the vial in its original packaging, protect it from light, and avoid freezing or shaking the solution. Do not use the product if it has been exposed to temperatures outside the recommended range.

Meriofert is supplied as an injectable solution for intramuscular or subcutaneous injection. Administration is performed by a qualified healthcare professional following aseptic technique and the dosing schedule prescribed by the treating physician.

The most serious risks include ovarian hyperstimulation syndrome, which can be severe and lead to complications such as fluid accumulation, thrombosis, or ovarian torsion, and the possibility of multiple pregnancy. Prompt medical attention is required if severe abdominal pain, rapid weight gain, or shortness of breath occur.

Meriofert should not be used in patients with uncontrolled thyroid disease, active ovarian cysts, untreated pituitary tumors, or a known hypersensitivity to human gonadotropins. It is also contraindicated in individuals with a high risk of thromboembolic events unless carefully monitored.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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