Product image of Meriofert Pfs (Luteinising Hormone (Human), Follicle-Stimulating Hormone) supplied by GNH India

Meriofert Pfs

Active Ingredient:
Luteinising Hormone (Human), Follicle-Stimulating Hormone
Origin:
EU

Meriofert Pfs (Luteinising Hormone (Human), Follicle-Stimulating Hormone)

Luteinising Hormone (Human), Follicle-Stimulating Hormone, the active ingredient in Meriofert Pfs, is a gonadotropin presented as an injectable solution for intramuscular or subcutaneous use. It is employed in the management of infertility related to anovulation, assisted reproductive technologies such as IVF, and hypogonadotropic hypogonadism in both women and men.

GNH India supplies Meriofert Pfs as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, fertility clinics and pharmacies worldwide, ensuring quality assurance, traceability and adherence to EU regulatory standards through rigorous manufacturing and distribution processes.

Manufacturer / TM Owner

Ibsa Farmaceutici Italia

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Indications & Clinical Uses

Meriofert Pfs contains LH and FSH, gonadotropins that act on the reproductive endocrine axis.

  • Infertility due to anovulation: stimulates follicular growth and ovulation to restore fertility.
  • Assisted reproductive technology (e.g., IVF): supports controlled ovarian stimulation for oocyte retrieval.
  • Hypogonadotropic hypogonadism: replaces deficient gonadotropins to induce gametogenesis and sex‑steroid production.

How It Works

  • The LH and FSH components of Meriofert Pfs bind to their respective receptors on ovarian (or testicular) cells. Activation of the FSH receptor promotes follicular development, estrogen synthesis, and ovulation, while LH receptor activation triggers luteinization, progesterone secretion, and testosterone production, thereby restoring normal reproductive hormonal signaling.

Side Effects

Adverse reactions may occur with any injectable gonadotropin preparation.

Common Side Effects

  • Injection site pain or bruising.
  • Headache.
  • Mild abdominal discomfort.
  • Nausea.

Serious or Rare Side Effects

  • Severe ovarian hyperstimulation syndrome (OHSS).
  • Thromboembolic events.
  • Allergic reactions including anaphylaxis.
  • Multiple pregnancy.
  • Persistent severe abdominal pain.

Precautions & Warnings

When using Meriofert Pfs, clinicians should observe several safety measures.

  • Pregnancy testing: confirm non‑pregnant status before initiating therapy.
  • Ovarian monitoring: perform serial ultrasound to detect hyperstimulation.
  • Thyroid function: assess in patients with known thyroid disorders.
  • Allergy: avoid in individuals with known hypersensitivity to gonadotropins.
  • Cancer history: use cautiously in estrogen‑sensitive malignancies.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Potential drug interactions may affect the efficacy or safety of Meriofert Pfs.

Major Interactions (Avoid)

  • GnRH antagonists: may blunt the intended gonadotropin response.
  • Oral contraceptives: suppress endogenous LH/FSH, reducing effectiveness.
  • High‑dose estrogen therapy: can antagonize gonadotropin action.

Moderate Interactions (Monitor Closely)

  • Anticoagulants: monitor for thrombotic risk if OHSS develops.
  • Thyroid hormone replacement: dosage may need adjustment during treatment.

Frequently Asked Questions

Meriofert Pfs is a combination of human luteinising hormone and follicle‑stimulating hormone used to treat infertility caused by anovulation, to support assisted reproductive technologies such as in‑vitro fertilisation, and to replace deficient gonadotropins in hypogonadotropic hypogonadism.

Both hormones bind to specific receptors on ovarian or testicular cells. FSH stimulates follicular growth, estrogen production and ovulation, while LH triggers luteinisation, progesterone secretion and testosterone synthesis, thereby restoring normal reproductive hormone cycles.

The dose of Meriofert Pfs is individualized. A qualified prescriber determines the amount, frequency and duration based on the patient’s clinical condition, response to therapy and monitoring results.

Meriofert Pfs is intended for use before conception to achieve pregnancy. It is not recommended during pregnancy, and safety during breastfeeding has not been established. Clinicians should evaluate risks and benefits before prescribing.

To order, submit an enquiry on the Meriofert Pfs product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain where required) and any necessary import documentation.

Meriofert Pfs combines LH and FSH in a single injectable, whereas some alternatives provide only one hormone or require separate preparations. The combined formulation can simplify dosing schedules and may improve patient convenience, but choice depends on individual treatment protocols and physician preference.

Meriofert Pfs should be stored at 2‑8 °C, protected from light, and must not be frozen or shaken. Keep the product in its original packaging until use to maintain stability.

The medication is supplied as an injectable solution for intramuscular or subcutaneous injection. Administration is performed by a qualified healthcare professional following aseptic technique and the dosing schedule prescribed by the treating physician.

Serious risks include severe ovarian hyperstimulation syndrome, thromboembolic events, allergic reactions such as anaphylaxis, and the possibility of multiple pregnancy. Patients should be closely monitored for these complications during treatment.

Meriofert Pfs is contraindicated in individuals with known hypersensitivity to gonadotropins, in patients with active ovarian cysts or severe ovarian disease, and in those with estrogen‑sensitive malignancies unless specifically advised by a specialist.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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