Product image of Meriofert Set (Follicle-Stimulating Hormone, Luteinising Hormone) supplied by GNH India

Meriofert Set

Active Ingredient:
Follicle-Stimulating Hormone, Luteinising Hormone
Origin:
EU

Meriofert Set (Follicle-Stimulating Hormone, Luteinising Hormone)

Follicle-Stimulating Hormone and Luteinising Hormone, the active ingredient in Meriofert Set, is a gonadotropin presented as a sterile injectable solution for subcutaneous use. It is employed in fertility hormone therapy to address anovulation and to support controlled ovarian stimulation in assisted reproductive technologies.
GNH India supplies Meriofert Set as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Ibsa Farmaceutici Italia

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Indications & Clinical Uses

Meriofert Set is a gonadotropin used in reproductive medicine to stimulate ovarian function.

  • Infertility due to anovulation: promotes follicular development and induces ovulation.
  • Controlled ovarian stimulation for assisted reproductive technologies: enhances follicle growth to optimize egg retrieval.
  • Ovulation induction in polycystic ovary syndrome: restores regular ovulatory cycles for conception.

How It Works

  • Follicle‑Stimulating Hormone and Luteinising Hormone bind to their respective FSH and LH receptors on ovarian granulosa and theca cells. This activation triggers intracellular signaling that promotes follicular maturation, estradiol synthesis, and the luteinising surge required for ovulation, thereby facilitating oocyte release for fertilisation.

Side Effects

Adverse reactions may occur with gonadotropin therapy and should be monitored.

Common Side Effects

  • Injection site pain or erythema: mild local discomfort after subcutaneous administration.
  • Abdominal discomfort or bloating: transient gastrointestinal sensations.
  • Nausea or mild headache: occasional systemic symptoms.
  • Mild ovarian hyperstimulation syndrome: ovarian enlargement with mild fluid shift.

Serious or Rare Side Effects

  • Severe ovarian hyperstimulation syndrome: marked ovarian enlargement, ascites, or thromboembolic complications.
  • Allergic reactions including anaphylaxis: rash, urticaria, respiratory distress.
  • Multiple pregnancy: increased risk of twins or higher‑order gestations.
  • Ectopic pregnancy: rare occurrence requiring prompt evaluation.

Precautions & Warnings

Careful patient assessment and monitoring are essential when using Meriofert Set.

  • Pregnancy testing: confirm non‑pregnant status before initiating therapy.
  • Ovarian monitoring: perform serial ultrasound to assess follicular response and prevent overstimulation.
  • Thromboembolic risk: evaluate history of clotting disorders before treatment.
  • Allergy assessment: screen for hypersensitivity to gonadotropin preparations.
  • Multiple pregnancy counseling: discuss the possibility of twins or higher‑order gestations.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Potential drug interactions may affect the efficacy or safety of Meriofert Set.

Major Interactions (Avoid)

  • GnRH antagonists: can diminish the stimulatory effect of FSH/LH therapy.
  • Oral contraceptives: suppress endogenous gonadotropin release, interfering with ovarian stimulation.
  • High‑dose estrogen therapy: may antagonize ovarian response to gonadotropins.

Moderate Interactions (Monitor Closely)

  • Thyroid hormone replacement: monitor thyroid function as gonadotropins can influence metabolism.
  • Anticoagulants: increased vigilance for thrombotic events during ovarian hyperstimulation.
  • Diuretics: may alter fluid balance during stimulation, requiring observation.

Frequently Asked Questions

Meriofert Set contains follicle‑stimulating hormone and luteinising hormone and is used in fertility hormone therapy to treat infertility caused by anovulation and to support controlled ovarian stimulation in assisted reproductive technologies such as in‑vitro fertilisation.

The two hormones bind to specific FSH and LH receptors on ovarian cells, activating signaling pathways that promote follicular growth, estradiol production and the luteinising surge that triggers ovulation, thereby facilitating the release of mature oocytes for fertilisation.

The dose of Meriofert Set is individualized. A qualified prescriber determines the amount and frequency based on the patient’s ovarian response, treatment protocol and clinical goals, and adjusts it according to monitoring results.

Meriofert Set is intended for use before conception to induce ovulation. It is not administered during an established pregnancy, and safety during breastfeeding has not been established, so use should be avoided in those situations unless specifically directed by a specialist.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain where required) and any necessary import documentation.

Meriofert Set combines both FSH and LH activity in a single injectable, offering a convenient alternative to using separate FSH and LH preparations. This can simplify dosing schedules and may improve patient compliance compared with regimens that require multiple products.

Meriofert Set should be stored refrigerated at 2‑8 °C, protected from light, and must not be frozen or shaken. Keep the product in its original packaging until use to maintain stability.

The medication is supplied as a sterile solution for subcutaneous injection. It is typically administered by a healthcare professional or trained patient using a pre‑filled syringe or vial, following aseptic technique and the dosing schedule prescribed.

The most serious risks include severe ovarian hyperstimulation syndrome, which can cause significant fluid shifts and thromboembolic events, as well as rare allergic reactions such as anaphylaxis and the possibility of multiple or ectopic pregnancies, all of which require prompt medical attention.

Meriofert Set is contraindicated in patients with known hypersensitivity to gonadotropins, active ovarian cysts, uncontrolled thyroid disease, or a history of severe ovarian hyperstimulation syndrome. It should also be avoided in women who are already pregnant.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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