Product image of Meriofert Set (Luteinising Hormone (Human), Follicle-Stimulating Hormone) supplied by GNH India

Meriofert Set

Active Ingredient:
Luteinising Hormone (Human), Follicle-Stimulating Hormone
Origin:
EU

Meriofert Set (Luteinising Hormone (Human), Follicle-Stimulating Hormone)

Human luteinising hormone (Human) and Follicle‑stimulating hormone, the active ingredients in Meriofert Set, are gonadotropins presented as an injectable solution for intramuscular and subcutaneous use. They are employed to treat infertility caused by anovulation and to support controlled ovarian stimulation in assisted reproductive technologies.

GNH India supplies Meriofert Set as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to EU quality standards and provides cold‑chain logistics for biologic products.

Manufacturer / TM Owner

Ibsa Farmaceutici Italia

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Indications & Clinical Uses

Meriofert Set, a gonadotropin acting on the reproductive hormone pathway, is indicated for:

  • Infertility due to anovulation: stimulates follicular development to enable ovulation.
  • Controlled ovarian stimulation for assisted reproductive technologies: promotes multiple follicle growth for IVF cycles.
  • Induction of ovulation in women with luteinising hormone deficiency: replaces deficient LH to trigger ovulation.

How It Works

  • Meriofert Set contains human luteinising hormone and follicle‑stimulating hormone that bind to LH and FSH receptors on ovarian granulosa and theca cells. Activation of these receptors initiates intracellular signaling that drives follicular maturation, estrogen synthesis, and the final ovulatory surge, thereby facilitating oocyte release and supporting reproductive cycles.

Side Effects

Adverse reactions reported with Meriofert Set are generally related to its hormonal activity and injection site.

Common Side Effects

  • Injection site pain or erythema.
  • Mild abdominal discomfort or bloating.
  • Headache.
  • Nausea.
  • Transient ovarian hyperstimulation (mild).

Serious or Rare Side Effects

  • Ovarian hyperstimulation syndrome (severe).
  • Multiple pregnancy.
  • Allergic reaction or anaphylaxis.
  • Thromboembolic events.
  • Ectopic pregnancy.

Precautions & Warnings

Before initiating therapy, clinicians should consider the following precautions:

  • Baseline ovarian assessment: perform ultrasound to evaluate follicular status.
  • Hormone monitoring: regularly measure estradiol levels during treatment.
  • Hypersensitivity: avoid in patients with known allergy to the product or its excipients.
  • Ovarian cysts: use caution in women with existing ovarian cysts.
  • Thyroid disease: assess thyroid function as gonadotropin response may be altered.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Meriofert Set may interact with other medications that affect ovarian response or coagulation.

Major Interactions (Avoid)

  • Concurrent use of other gonadotropins: increases risk of severe ovarian hyperstimulation.
  • High‑dose estrogen therapy: may blunt the intended ovulatory response.

Moderate Interactions (Monitor Closely)

  • Anticoagulants: monitor for thrombotic complications.
  • Corticosteroids: may alter hormonal dynamics, requiring dose adjustment.
  • Thyroid hormone replacement: ensure euthyroid status to optimise response.

Frequently Asked Questions

Meriofert Set is a combination of human luteinising hormone and follicle‑stimulating hormone used to treat infertility caused by anovulation, to support controlled ovarian stimulation in assisted reproductive technologies such as IVF, and to induce ovulation in women who lack sufficient endogenous LH.

Both hormones bind to specific receptors on ovarian cells. Follicle‑stimulating hormone promotes growth and maturation of ovarian follicles, while luteinising hormone triggers the final maturation and release of the oocyte. Together they enhance estrogen production and coordinate the ovulatory process.

The dose of Meriofert Set is individualized. A qualified prescriber determines the amount, frequency, and duration based on the patient’s ovarian response, treatment protocol, and clinical goals. No standard regimen is provided in public information.

Meriofert Set is intended for use before conception to facilitate ovulation. Its safety during pregnancy has not been established, and it is not recommended for use while pregnant. Limited data are available for breastfeeding, so the product should be avoided unless the prescriber decides the benefit outweighs potential risk.

To place an order, submit an enquiry on the Meriofert Set product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, cold‑chain shipping details and any necessary import documentation.

Meriofert Set combines both LH and FSH in a single injectable formulation, whereas some alternatives provide only FSH or separate LH preparations. This combined approach can simplify dosing schedules and may better mimic natural ovarian physiology, but the choice depends on individual patient characteristics and the treating physician’s protocol.

Meriofert Set must be stored at 2‑8 °C in a refrigerator, protected from light. Do not freeze or shake the vial. Before use, allow the product to reach room temperature if required, and inspect for particulate matter or discoloration. Follow aseptic technique when preparing the injection.

The product is supplied as an injectable solution for intramuscular or subcutaneous injection. Administration is performed by a qualified healthcare professional using aseptic technique. The injection site and volume are selected according to the prescribed dose and the patient’s treatment plan.

Serious risks include severe ovarian hyperstimulation syndrome, which can cause fluid accumulation, electrolyte imbalance, and thromboembolic events, as well as multiple pregnancy and rare allergic reactions such as anaphylaxis. Patients should be monitored closely for abdominal pain, rapid weight gain, shortness of breath, or signs of allergic response.

Meriofert Set is contraindicated in individuals with known hypersensitivity to the product or any of its excipients, in women with active ovarian cysts that could be aggravated, and in patients with uncontrolled thyroid disease or severe cardiovascular conditions where hormonal stimulation poses additional risk.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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