Product image of Meropenem Bradex (Meropenem Anhydrous) supplied by GNH India

Meropenem Bradex

Active Ingredient:
Meropenem Anhydrous
Origin:
EU

Meropenem Bradex (Meropenem Anhydrous)

Meropenem, the active ingredient in Meropenem Bradex, is a carbapenem antibiotic presented as an injectable solution for intravenous use. It provides broad‑spectrum bactericidal activity against serious Gram‑negative and Gram‑positive infections in hospitalized patients requiring parenteral therapy.

GNH India supplies Meropenem Bradex as a licensed, GDP‑compliant international pharmaceutical supplier, delivering the product to hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide. Originating from the European Union, the product meets EU pharmacopeial specifications.

Manufacturer / TM Owner

Bradex S.A.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Meropenem Bradex is a carbapenem antibiotic indicated for serious bacterial infections affecting various organ systems.

  • Complicated intra‑abdominal infections: achieves bacterial eradication in severe abdominal infections.
  • Complicated urinary tract infections: clears resistant uropathogens causing pyelonephritis and cystitis.
  • Bacterial meningitis: penetrates the cerebrospinal fluid to treat meningitic pathogens.
  • Hospital‑acquired pneumonia: provides coverage for multidrug‑resistant respiratory bacteria.
  • Sepsis: rapidly reduces bacterial load in systemic infections.

How It Works

  • Meropenem binds with high affinity to penicillin‑binding proteins (PBPs) on bacterial cell walls, inhibiting the final transpeptidation step of peptidoglycan synthesis. This disruption weakens the cell wall, leading to osmotic instability and bacterial cell death. The drug is resistant to most β‑lactamases, giving it activity against a wide range of Gram‑negative, Gram‑positive and anaerobic organisms.

Side Effects

Adverse reactions may occur with any intravenous antibiotic and should be monitored during therapy.

Common Side Effects

  • Nausea
  • Diarrhea
  • Rash or pruritus
  • Headache
  • Elevated liver enzymes
  • Injection‑site phlebitis

Serious or Rare Side Effects

  • Anaphylactic or severe allergic reactions
  • Seizures, especially in patients with renal impairment
  • Clostridioides difficile‑associated colitis
  • Severe neutropenia or leukopenia
  • Acute renal failure
  • Hepatic failure or severe transaminase elevation

Precautions & Warnings

Use of Meropenem Bradex requires careful assessment of patient‑specific factors and monitoring.

  • Renal function: adjust dose in patients with impaired clearance.
  • Seizure risk: monitor individuals with a history of CNS disorders.
  • Allergy: avoid in patients with known carbapenem hypersensitivity.
  • Pregnancy: prescribe only when benefits outweigh potential risks.
  • Antimicrobial stewardship: limit use to confirmed bacterial infections.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze.

Avoid Interactions

Meropenem Bradex can interact with other medicines, influencing efficacy or safety.

Major Interactions (Avoid)

  • Valproic acid: may reduce serum valproate concentrations.
  • Probenecid: can increase meropenem plasma levels, raising toxicity risk.
  • Renally toxic drugs (e.g., aminoglycosides): concurrent use may exacerbate nephrotoxicity.

Moderate Interactions (Monitor Closely)

  • Loop diuretics: monitor renal function and electrolytes.
  • Anticoagulants (e.g., warfarin): observe coagulation parameters for potential changes.

Frequently Asked Questions

Meropenem Bradex is employed for serious bacterial infections such as complicated intra‑abdominal infections, complicated urinary tract infections, bacterial meningitis, hospital‑acquired pneumonia, and sepsis. It is reserved for cases where broad‑spectrum, parenteral therapy is required, particularly in hospitalized patients.

Meropenem inhibits bacterial cell‑wall synthesis by binding to penicillin‑binding proteins. This blocks the final cross‑linking step of peptidoglycan formation, causing cell‑wall weakness, osmotic lysis, and rapid bacterial death. Its structure also confers resistance to most β‑lactamases.

The dosing regimen for Meropenem Bradex is determined by the prescribing clinician based on infection severity, pathogen susceptibility, patient weight, renal function, and other clinical factors. Only a qualified healthcare professional should set the appropriate dose.

Safety data in pregnancy and lactation are limited. Meropenem should be used only if the potential benefit to the mother outweighs any possible risk to the fetus or infant. Clinicians must evaluate each case individually and discuss risks with the patient.

To place an order, submit an enquiry on the Meropenem Bradex product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.

Meropenem offers a broad spectrum similar to imipenem‑cilastatin and ertapenem but has a slightly higher activity against Pseudomonas aeruginosa and better stability against many β‑lactamases. Choice among carbapenems depends on local resistance patterns, dosing convenience, and patient‑specific factors such as renal function.

Meropenem Bradex should be stored refrigerated at 2‑8 °C. Keep the vials in their original packaging, protect from light, and avoid freezing or shaking the solution. Do not use the product if it has been exposed to temperatures outside this range.

Meropenem Bradex is given by intravenous infusion. The infusion rate and duration are set by the treating physician, typically over 15‑30 minutes, and may be adjusted according to the patient’s renal function and clinical response.

Serious adverse events include anaphylaxis, severe seizures (especially in patients with renal impairment), Clostridioides difficile‑associated colitis, and significant hepatic or renal dysfunction. Prompt recognition and discontinuation are essential if any of these reactions occur.

Meropenem Bradex is contraindicated in patients with a known hypersensitivity to meropenem, other carbapenems, or any β‑lactam antibiotics. Caution is also advised for individuals with a history of seizures, severe renal impairment, or those receiving interacting medications listed under major interactions.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.