Product image of Meropenem Steriscience (Meropenem) supplied by GNH India

Meropenem Steriscience

Active Ingredient:
Meropenem
Origin:
EU

Meropenem Steriscience (Meropenem)

Meropenem, the active ingredient in Meropenem Steriscience, is a carbapenem antibiotic presented as an injectable solution for intravenous use. It treats severe bacterial infections such as complicated intra‑abdominal infections, complicated urinary tract infections, nosocomial pneumonia, septicemia and meningitis in hospitalized patients. It is indicated for use in adult and pediatric patients when alternative therapies are unsuitable.

GNH India supplies Meropenem Steriscience as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide, ensuring quality‑assured products that meet European regulatory standards.

Manufacturer / TM Owner

Steriscience B.V.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Meropenem is a broad‑spectrum carbapenem antibiotic employed to manage serious bacterial infections across several organ systems.

  • Complicated intra‑abdominal infections: achieves bacterial eradication in severe abdominal sepsis and peritonitis.
  • Complicated urinary tract infections: clears resistant Gram‑negative pathogens causing pyelonephritis and cystitis.
  • Nosocomial pneumonia: treats hospital‑acquired and ventilator‑associated pneumonia caused by multidrug‑resistant organisms.
  • Septicemia: provides rapid bactericidal activity in bloodstream infections with high mortality risk.
  • Meningitis: penetrates the cerebrospinal fluid to eradicate pathogens responsible for bacterial meningitis.

How It Works

  • Meropenem binds with high affinity to penicillin‑binding proteins (PBPs) on bacterial cell walls, inhibiting the final transpeptidation step of peptidoglycan synthesis. This disruption leads to cell‑wall weakening and bacterial lysis. The molecule is stable against most β‑lactamases, giving it activity against a wide range of Gram‑negative and Gram‑positive organisms, including many resistant strains.

Side Effects

Meropenem may be associated with a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Nausea
  • Diarrhea
  • Rash or pruritus
  • Headache
  • Injection site pain or phlebitis
  • Elevated liver enzymes (ALT/AST)

Serious or Rare Side Effects

  • Seizures, especially in patients with renal impairment or CNS disorders
  • Clostridioides difficile‑associated colitis
  • Anaphylactic or severe hypersensitivity reactions
  • Neutropenia or agranulocytosis
  • Hepatic failure or severe transaminase elevation

Precautions & Warnings

Before initiating therapy, clinicians should consider several safety measures.

  • Renal function assessment: adjust dose in patients with impaired clearance.
  • Hepatic monitoring: observe liver enzymes during prolonged therapy.
  • CNS disorders: use caution in patients with seizure history.
  • Concomitant nephrotoxic drugs: avoid or monitor closely to reduce renal toxicity.
  • Known hypersensitivity: contraindicated in patients with allergy to carbapenems or beta‑lactams.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Meropenem can interact with other medicines, requiring attention to avoid reduced efficacy or increased toxicity.

Major Interactions (Avoid)

  • Valproic acid: carbapenems lower serum valproate levels, risking seizure breakthrough.
  • Probenecid: may increase meropenem plasma concentrations, enhancing toxicity.
  • Renal toxic agents (e.g., aminoglycosides, amphotericin B): combined use can exacerbate nephrotoxicity.

Moderate Interactions (Monitor Closely)

  • Diuretics: may affect renal clearance, requiring dose adjustment.
  • Anticoagulants (warfarin): monitor INR as meropenem may alter coagulation parameters.

Frequently Asked Questions

Meropenem Steriscience is an intravenous carbapenem antibiotic indicated for the treatment of severe bacterial infections such as complicated intra‑abdominal infections, complicated urinary tract infections, hospital‑acquired pneumonia, septicemia and bacterial meningitis, particularly when other antimicrobial options are unsuitable.

Meropenem exerts its antibacterial effect by binding to penicillin‑binding proteins on the bacterial cell wall, blocking the final step of peptidoglycan cross‑linking. This inhibition weakens the cell wall, leading to osmotic rupture and bacterial death, and it remains active against many β‑lactamase‑producing organisms.

The prescribed dose of Meropenem Steriscience is determined by the treating physician based on the type and severity of infection, the patient’s renal and hepatic function, age, weight and any concomitant medications. Dosage regimens are individualized and should follow current clinical guidelines.

The safety of Meropenem in pregnancy and lactation has not been definitively established; it is classified as pregnancy category unknown. Clinicians should weigh potential benefits against possible risks and consider alternative therapies when safer options are available.

To order Meropenem Steriscience, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain logistics if needed) and required import documentation.

Meropenem shares a broad spectrum with other carbapenems such as imipenem‑cilastatin and ertapenem, but it offers enhanced stability against many β‑lactamases and a slightly lower risk of nephrotoxicity compared with imipenem. Compared with non‑carbapenem agents, it provides superior activity against multidrug‑resistant Gram‑negative bacteria, though cost and local resistance patterns influence selection.

Meropenem Steriscience should be stored at 2‑8 °C in a refrigerator, protected from light. The vial must remain in its original packaging, must not be frozen, and should be gently shaken only if required for reconstitution, following the manufacturer’s instructions.

Meropenem Steriscience is supplied as an injectable solution for intravenous infusion. It is typically administered over a 15‑30‑minute infusion period, with the exact rate and duration determined by the prescribing clinician based on infection severity and patient-specific factors.

Serious adverse events include seizures (especially in patients with renal impairment or pre‑existing CNS disorders), Clostridioides difficile‑associated colitis, severe hypersensitivity reactions such as anaphylaxis, neutropenia or agranulocytosis, and hepatic failure. Prompt medical attention is required if any of these occur.

Meropenem Steriscience is contraindicated in individuals with a known hypersensitivity to meropenem, other carbapenems, or any β‑lactam antibiotics. Caution is also advised for patients with a history of seizures, severe renal impairment, or those receiving concomitant nephrotoxic agents.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.